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Wellbutrin (Bupropion)

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Wellbutrin is used in the treatment of depression and smoking addiction. This medicine helps by increasing the level of chemical messengers in the brain that relax the nerves and have a calming effect on the brain.

Other names for this medication:
Aplenzin, Budeprion, Bupdep, Bupraset, Bupron, Bupropion, Ession, Nicotex, Smoquit, Unidep, Zyban

Similar Products:
Aceon, Ceclor, Daklinza, Arcoxia, Astelin

Also known as: Bupropion


{name} SR is an antidepressant used to treat major depressive disorder and seasonal affective disorder. The Zyban brand of bupropion is used to help people stop smoking by reducing cravings and other withdrawal effects.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Too much of this medicine can increase your risk of a seizure.

You may take Wellbutrin XL with or without food.

Swallow the extended-release tablet whole and do not crush, chew, or break it.

You should not change your dose or stop using Wellbutrin XL suddenly, unless you have a seizure while taking this medicine. Stopping suddenly can cause unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

If you take Zyban to help you stop smoking, you may continue to smoke for about 1 week after you start the medicine. Set a date to quit smoking during the first 2 weeks of treatment. Talk to your doctor if you have trouble quitting after taking Zyban for 7 to 12 weeks.

Your doctor may prescribe a nicotine replacement product (such as patches or gum) to help you stop smoking. Start using the nicotine replacement product on the same day you stop (quit) smoking or using tobacco products.

Some people taking Wellbutrin XL (Wellbutrin or Zyban) have had high blood pressure that is severe, especially when also using a nicotine replacement product (patch or gum). Your blood pressure may need to be checked before and during treatment with this medicine.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

You may have nicotine withdrawal symptoms when you stop smoking, including: increased appetite, weight gain, trouble sleeping, trouble concentrating, slower heart rate, having the urge to smoke, and feeling anxious, restless, depressed, angry, frustrated, or irritated. These symptoms may occur with or without using medication such as Zyban.

Smoking cessation may also cause new or worsening mental health problems, such as depression.

This medicine may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use Wellbutrin XL.

Store at room temperature away from moisture, heat, and light.

Detailed Wellbutrin XL dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Wellbutrin SR can be fatal. Overdose symptoms may include muscle stiffness, hallucinations, fast or uneven heartbeat, shallow breathing, or fainting.


Store at room temperature below 25 degrees C (77 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Wellbutrin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Drinking alcohol with Wellbutrin XL may increase your risk of seizures. If you drink alcohol regularly, talk with your doctor before changing the amount you drink. This medicine can also cause seizures in a regular drinker who suddenly stops drinking at the start of treatment with this medicine.

Avoid driving or hazardous activity until you know how Wellbutrin XL will affect you. Your reactions could be impaired.

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Portable capillary electrophoresis instrument with contactless conductivity detection for on-site analysis of small volumes of biological fluids. Of the 11 potential N-glycosylation sites, Asn(21), Asn(61), Asn(109), Asn(135), Asn(205), Asn(357), Asn(361), Asn(531), and Asn(542) are glycosylated but not Asn(224) and Asn(368). Reversible cardiomyopathy induced by psychotropic drugs: case report and literature overview. In contrast, the mutant endosperm appears normal in morphology, cell structure, starch, lipid and protein accumulation. Oral and systematic manifestations of pellagra (report of a case). Genetic associations for gilt growth, compositional, and structural soundness traits with sow longevity and lifetime reproductive performance. The absence of Ku and the consequent great shortening of telomeres had no detectable influence either on the rate of VSG switching or on the silencing of the telomeric promoters of the VSG subset that is expressed in the tsetse fly.

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The structure of the new antibiotic was determined by spectroscopic methods and by comparison of the NMR data with those of the structurally related gamma-indomycinone. Cytochrome P450 (P450) BM3, from Bacillus megaterium, catalyzes a wide range of chemical reactions and is routinely used as a model system to study mammalian P450 reactions and structure. Toxicokinetic modeling aided in characterizing the complex metabolism and multiple metabolites that contribute to PCE toxicity. SSEH occurring anterior to the spinal cord in the cervical region with spontaneous improvement is even more rare. Mutations in the RPN4 Pdr1p/Pdr3p binding sites lead to decreased expression of the proteasome RPT6 gene and to defective ubiquitin-mediated proteolysis. The effect of intraocular irrigating solutions on lens clarity in normal and diabetic rabbits. A DVH parameter of Vx was the percentage of the total organ volume exceeding x radiation dose. In the case using the silyl enol ether derived from the thioester, 2,6-di-tert-butylpyridine significantly improved the yields of the aldol adducts. These findings mirror results from nonhuman primates and demonstrate that hierarchies are detrimental to cooperation.

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The focus of the assessment on clinical encounters and behaviours important for collaboration provided opportunities for students to engage with the health care team and highlighted the role of teamwork in these encounters. Although the mean birthweight of Korle-Bu babies was lower than those of USA and UK babies, it was comparable with those from other developing countries. Adsorption and desorption behavior of glyphosate, s-metolachlor and epoxiconazole was investigated on maize mulch residues decomposed under laboratory and field conditions. Adsorption experiments suggested that NiO-SiO2 composite particles were powerful adsorbents for removal of Congo red from water, with a maximum adsorption capacity of 204.1 mg/g. Autoimmune T-lymphocyte proliferative response to mouse myoglobin. Pigmentation of a skin graft placed over a wound from excision of a pigmented nevus. We identified and determined predictors of dietary patterns in low-income black and Hispanic adults with diagnosed diabetes. To examine the current and future therapeutic option of HDL-based therapies. Discrepancies were confirmed by two dedicated breast radiologists after repeat imaging, short-interval follow-up imaging, or biopsy. Genetic variation analysis of wild populations of grass carp (Ctenopharyngodon idella) using microsatellite markers.

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Further, Bap29,31 deletion, as well as a Nex-domain dominant-negative mutant, curtailed the activation of downstream caspases (IETDase and DEVDase) and cell death in response to E1A. Preoperative, intraoperative and postoperative developments are presented with supporting evidence in these continually evolving fields. The ensuing vaccine responses and the protective efficacy of FM1 were superior in PR8 infection-primed mice compared to PR8 immunization-primed or unprimed mice. Imagery rescripting appears to be a valuable adjunct to conventional CBT in working with cases where there is an early history of trauma. Larger scale gene-environmental interaction studies are recommended to confirm results and Genotyping is recommended during selection of agricultural pesticide workers to exclude high risk group. ImmTAC-redirected tumour cell killing induces and potentiates antigen cross-presentation by dendritic cells. pneumoniae (P(fcsK)::def1) strain was observed, confirming the essential nature of PDF in this organism. Clinical neurosensory testing such as two-point discrimination, static light touch, brush directional stroke, pin-prick, thermal discrimination and dental vitality tests were used for evaluation.

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Changes in coagulation and fibrinolysis after orthotopic canine liver homotransplantation. In contrast to its strong labeling of cutaneous melanomas, S100 immunolabeling of uveal melanomas was weak and variable. They also display low numbers of lamina propria cells and TCRalphabeta intraepithelial lymphocytes, and low levels of secretory IgA. cloacae fatty acid metabolism on the suppression of Pythium sporangium germination and subsequent plant infection. Galvanic corrosion between NiTi and beta titanium were investigated. The goal of the present study was to determine whether cytokines in the peripheral blood of naive NOD mice correlate with the disease process and thereby would provide a marker for monitoring disease activity.

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Minute treatment with tinidazole and ornidazole in children with amebic dysentery. Suppression of conditioned fear by administration of CRF receptor antagonist CP-154,526. To investigate the root canal configuration of mandibular anterior teeth with cone-beam computed tomography (CBCT). Expression of miR-1, miR-133 and miR-218 was greatly decreased in bladder cancer than normal bladder tissue. Impaired epicardial activation-repolarization coupling contributes to the proarrhythmic effects of hypokalaemia and dofetilide in guinea pig ventricles. The prospects for state and local governments playing a broader role in health care in the 1980s. The Ah receptor (AHR) mediates the metabolic adaptation to a number of planar aromatic chemicals.

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We use gene replacements to optimize maintenance of expression level and show that under these conditions the native translocases are the most effective for their native repeat unit, being, respectively, 64-fold and 4-fold more effective than the next best. Whole-exome sequencing was performed using DNA from 7 pituitary NFAs and leukocyte samples obtained from the same patients. Ifosfamide, carboplatin and etoposide combined with 41.8 degrees C whole body hyperthermia for malignant pleural mesothelioma. Semisolid intake was directly measured and breast milk intake was quantified by test weighing method. The irrigation fluid temperature, room temperature, intensity of the microscope light, and the distance of the microscope from the brain surface were kept constant. by Multiple Endonuclease Restriction Real-Time Loop-Mediated Isothermal Amplification Technique.

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Human respiratory syncytial virus (hRSV) is a member of paramyxovirus and its crystal structure of HR1 and HR2 six-helix bundle was solved lately. MicroRNA-140-3p inhibits proliferation, migration and invasion of lung cancer cells by targeting ATP6AP2. At the end of surgery, patient was extubated after adequate reversal from neuromuscular blockade. The position of the mandibular condyle in the articular eminence in wearers of distal bite activators. The concentration of factor VIII and partial thromboplastin times became normal and have remained normal for 140 days after orthotopic tranplantation of a normal liver to a hemophilic dog. Lymphatic mapping and sentinel node biopsy of operable breast cancer. Suggestive evidence for the induction of colonic aberrant crypts in mice fed sodium nitrite. Serum total cholesterol and tumor total cholesterol were detected using the cholesterol oxidase/p- aminophenazone (CHOD-PAP) method. A phospho-null mutation (T58A) revealed that this residue is important but not sufficient for PKG activation by PKC.

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Continuing management of conductive hearing loss during language development. Alanine scan of the peptide antibiotic feglymycin: assessment of amino acid side chains contributing to antimicrobial activity. Long range dicorrelated stopping of relativistic electrons in ultradense plasmas. Clinical observations on the action of the most common diuretics active by oral route. Therefore, the intermuscular cross-correlation and beta-band coherence may be a potential index for assessing muscle fatigue and monitoring the central control of motor function during dynamic fatiguing exercise. For simple, well-reduced fractures the choice of implant is not critical. The main outcome measures were mortality status at discharge from hospital and two years later. Fibrinolytic activity of salivary euglobulin fractions precipitated at pH 5.9 or 6.4 before and after mixing with blood. In this study we investigated the kinematics of electromagnetic fields with various configurations of the magnetic and electric fields in systems with spherical and cylindrical symmetry using the exact solutions to the diffusion equation for the electromagnetic field in systems with moving boundaries.

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Morphological study and comprehensive cellular constituents of milky spots in the human omentum. ineichi, the only ones of which aspects of the life-cycles are known, experimentally develop in phlebotomine sand flies. This mixed-methods study examined gender differences in the social motivation and friendship experiences of adolescent boys and girls with autism relative to those without autism, all educated within special education settings. Animals were caged with males of proven fertility and subsequently killed at day 14 of pregnancy and the number of implantation sites counted. Retention of previously encoded information and recognition, however, were intact. The WST-8 assay is fast, simple, and more reproducible and sensitive than the MTT assay. The concentration of antibody in the lacteal secretions, represented by immunoglobulin G specific for each of the 3 vaccine antigens, was monitored during the 18-week experimental period by enzyme-linked immunosorbent assay.

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Isolation of RNA from endometrial samples, reverse transcription, selective preamplification of full-length hCG/LH receptor mRNA and several shorter fragments of the receptor gene (exons 1-11, 1-10, and 1-5), nested polymerase chain reaction with internal primers. Adequacy and verifiability of pharmaceutical mixtures and dose units by variographic analysis (Theory of Sampling) - A call for a regulatory paradigm shift. In peripheral lymphoid organs DCs also induce tolerance to antigens captured by receptors that mediate efficient uptake of proteins and dying cells. The rs9677 CC genotype could be correlated with a reduced response to statin therapy and seems to be involved in diabetes cardiomyopathy in female patients with T2D. Celesnik procedure in the surgical treatmewnt of bilateral complete clefts. Fetal macrosomia at the University College Hospital, Ibadan: a 3-year review. In addition to providing a mechanism that allows cells to contact the extracellular matrix, integrins also promote intracellular signals that stimulate and regulate cell movement. Warfarin therapy was discontinued 3 days before surgery to prevent excessive bleeding during the perioperative period. Bacterial vaginosis is a complex alteration of vaginal flora causing mild symptoms in women characterized by a milky vaginal discharge associated with a fishy odor worsened after unprotected vaginal coitus.

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Concurrently, the Institute for Health Metrics and Evaluation (IHME) has published estimates of development assistance for health (DAH) at the country-disease level for this same period of time. Tract tracing, using double-label immunocytochemistry, revealed the presence of a monosynaptic dopaminergic pathway projecting from the POA to the INF. Adolescent motherhood in Ethiopia has shown a generally declining trend over time. Records of 478 consecutive patients who underwent 1 026 percutaneous TACE procedures were retrospectively analyzed. Bilateral morphologic evaluation is useful in the evaluation of patients with NHL, HD, CA, and SA and is not indicated for patients with acute or chronic leukemia, myelodysplasia, MM, and other diseases. The importance of critical incident reporting - and how to do it. Unusual temperature dependence of hyperfine shifts and spin equilibrium in ferric myoglobin and hemoglobin derivatives. LH correlated negatively with IL-6, age, WC, duration of menopause and SHBG. To reveal the regional distribution pattern of AM fungi as driven by multiple environmental factors, and to understand the ecological importance of AM fungi in natural ecosystems, we conducted a field investigation on AM fungal abundance along environmental gradients in the arid and semi-arid grasslands of northern China. The effect of locally infused endotoxin on gracilis muscle glucose uptake was determined in anesthetized mongrel dogs.

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Concepts such as symptoms present specific representational challenges in the EMR. Serious seizure-related burns are reportedly common in cultures that use ground fire for cooking, heating, or ceremonial purposes. To establish the presence of membrane-type matrix metalloproteinases (MT-MMPs) in the cornea and their expression zyrtec d drug interactions in naive and immunized mice intracorneally infected with Pseudomonas aeruginosa. Dependence of bicellar system phase behavior and dynamics on anionic lipid concentration. This study provides evidence for the impact of PCV10 in clinical and X-Ray confirmed pneumonia in routine vaccination program in Brazil, after 3 years of vaccine introduction. Reduction of the Schiff bases formed between glucose, mannose or galactose with glutamic acid yields products related both structurally and biologically to agropine and to a derivative of agropine present in crown gall tumours. New procedures for the preparation of complexes of ribosomes with polyuridylic acid.

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Identification and characterization of corpuscular, soluble and secreted antigens of a Venezuelan isolate of Anaplasma marginale. The assay exhibited satisfactory accuracy and precision over the concentration range of 0.2-15 nM (70-5200 pg/ml) with a limit of quantification of 0.2 nM. Protective effect of bone marrow mesenchymal stem cells on PC12 cells apoptosis mediated by TAG1. We also estimated the cumulative risk during the lifetime of an individual mole by using a modification of the standard life table method. Compressive tests, carried out in static and cyclic mode under dry as well as wet conditions, revealed a strong impact of fiber reinforcement on compressive modulus and compressive stress. Women face unique pathologies and challenges related to the female genital tract (FGT), including vaginal infections and gynecologic cancers. Reutilization of paraformaldehyde tablets: assessment of their sterilizing effect.

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We implemented a video portal integrating videos from 500 US Hospital channels. Omega-3 polyunsaturated fatty acids preserve retinal function in type 2 diabetic mice. The aim of the research was to determine the effect of blackcurrant fruit and leaf extracts albenza dose children on the physical properties of the erythrocyte membranes and assess their antioxidant properties. We developed a time-resolved, discrete model to describe stochastic dynamics and study the approximation of non-linear dynamics in the context of timed Petri nets. We sought to analyse tunnel anatomy, dimensions and blood flow using cardiac magnetic resonance imaging (CMR). Inverse x-ray fluorescence holography was used to explore the local atomic order of a nearly perfect quasicrystal with composition Al70. The realization that both prophylactic drugs and attenuated vaccines control but do not eradicate infection with Eimeria encouraged development of a vaccine based upon maternal immunity. In the second application, Principal Component Analysis is applied to a final stage fermentation production facility. Acute Mountain Sickness (AMS) Knowledge Among High Altitude Marathon Runners Competing in the Everest Marathon.

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All substituents except for methylene occupied the 11beta-position. Chloroquine and hydroxychloroquine zithromax generic drug name exert beneficial effects in experimental PAH. Activation of the phagocyte nicotinamide adenine dinucleotide phosphate (NADPH) oxidase constitutes an emergency response to infectious threat and results in the generation of antimicrobial reactive oxidants. One is characterized by small uniform spherical ossicles resembling psammoma bodies (psammomatoid juvenile ossifying fibroma). The specimens were collected on mushrooms and mushroom-associated trees. Aim of the present study is to ascertain the importance of diminutive colorectal polyps and define the need for removal according to their characteristics and malignant potential.

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The lack of a potent and bioavailable anti-oxidant enzyme is a major challenge in studies on antioxidant therapy. We also need to know how this factor influences the volume and type of treatment planned, both for the individual skilled benchmark epidemiologist and practitioner, and for mean world extremes on the other hand. VP7, the rotavirus outer capsid glycoprotein, is a target of protective antibodies and is responsible for the calcium-dependent uncoating of the virus during cell entry. Nervous system disorders induced by occupational exposure to aluminium compounds: a literature review. The effects of socio-demographic characteristics, living arrangements, unemployment history and attitudes, and parental support are found to be specific to gender and labor market outcomes, while the effects of material deprivation are uniform across all such categories. Several different strains of Escherichia coli were grown on a variety of carbon sources under various growth conditions.

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The development of new compounds is not the answer, because many are based off existing structures to which bacteria have already developed resistance. We find that deletion of Lhx2 leads to significantly decreased numbers of cortical progenitors and premature neuronal differentiation. We studied ETS1 rs1128334 G/A and WDFY4 rs7097397 A/G gene polymorphisms in 329 patients with RA and 697 controls in a Chinese population. However, even among venomous snakes, different prey handling strategies are utilized, varying from the strike-and-hold behaviors exhibited by highly toxic elapid snakes to the rapid strike-and-release envenomation seen in viperid snakes. To investigate the biological mechanism of acupuncture directions, rapid resolution liquid chromatography coupled with quadrupole time-of-flight mass spectrometry-based will biaxin treat sinus infection metabonomic techniques are used to analyze the metabolic profiles of urine samples. Hemofiltration and peritoneal dialysis in infection-associated acute renal failure.

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To address this, in recent years the focus on the use of culture-independent methods based on the direct analysis of DNA (or RNA) has rapidly increased. Urinary tract infections are some of the most commonly treated bacterial infections in adults. Studies on microbial protein synthesis with Azotobacter vinelandii as the test organism. Death according to the social representations of health professionals. Approximately two to three times the minimal lethal dose (MLD) of type F toxin from either Langeland or nonproteolytic strains was cross-neutralized by 1,000 anti-MLD of type E antitoxin. The results obtained with both regimens as compared with GnRH agonists in long protocols are showing a reduction in the stimulation length, in the consumption of gonadotrophins and in the incidence of the OHSS. Using attenuated total reflectance (ATR)-FT-IR, the residual silanol groups in each hydrogels could be measured without drying procedures and it was found that electroosmotic mobility decreased with a reduction in the residual silanol groups. The removal system for the absorption of CO2 with amines and NH3 is an advanced air pollution control device to reduce greenhouse gas emissions.

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Based on an analysis of the present-day knowledge of the pathogenesis of stress, neurosis, and neurosis-like states, the paper highlights the spectrum of pharmacological activity and the mechanisms of action of the commonly used anxiolytics. Reversible physical and chemical manipulation of the prostaglandin receptor. The program provides rural interdisciplinary clinical experiences for health professions students in seven community sites. Fluorescence spectroscopy is not a sensitive method for detecting rejection in human heart transplant recipients. Although patient safety is a major problem, most health care organizations rely on spontaneous reporting, which detects only a small minority of adverse events. Innocuousness and effectiveness of injections of diluted hydrogen peroxide.

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Genome-wide cytosine methylation levels were monitored by reverse-phase HPLC, and results indicated reduced levels of methylated cytosine in NT-generated fetuses. Furthermore, the cognitive dysfunction is less and of shorter duration. Measurement modelling and mapping of arsenic bioaccessibility in Northampton, United Kingdom. Initial attempts to study matrix components and architecture of the biofilm matrix on gallstone surfaces were hindered by the auto-fluorescence of cholesterol. There is an association of homicide with mental disorder, most particularly with certain manifestations of schizophrenia, antisocial personality disorder and drug or alcohol abuse. Dietary glycemic load, insulin load, and weight loss in obese, insulin resistant adolescents: RESIST study. Weight and height deficiences of mentally backward and normal children. The connection between psychopathology and tinnitus is complex and not adequately studied.

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Expression of an antigen, recognized by a monoclonal antibody raised against PC13 embryonal carcinoma, is described in mouse preimplantation embryogenesis. This fusion was expressed in yeast cells and yielded the expected full-length protein product. Hemolysin BL (HBL) is a major virulence factor for Bacillus cereus group strains. Only at high hormone concentrations human proinsulin could displace human insulin from the insulin receptor. This work provides additional benchmark information for computational studies of this intriguing radical, as well as a reliable set of molecular constants for extrapolation of the transition frequencies of HO3 for future astronomical observations. In the quest for possible involvement of stem cell factor (SCF), a cytokine known to have multiple effects, in the pathogenesis of endometriosis, we evaluated concentrations of SCF in peritoneal fluid (PF) of women with or without endometriosis. Salmonella serotypes isolated from tortoises and frogs in Istanbul. A pterotic branch is widespread among catfishes and has been identified as a synapomorphy for siluriforms, but its presence in loricarioid catfishes has been disputed. Questionnaire study of a cohort of women who experienced a severe obstetric morbidity during pregnancy or labour (cases), compared with a cohort of women who did not (controls). The imidazole-based catalysts were significantly more active toward ROP than the thiazolium-based analogues.

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