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Sporanox (Itraconazole)
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Sporanox

Sporanox belongs to a group of medicines called antifungals. It works by stopping the growth of fungi and is used to treat infections of the mouth, throat, vagina, and other parts of the body including fingernails and toenails. It kills fungi by destroying the fungal cell membrane.

Other names for this medication:
Biospore, Candiloss, Candistat, Canditral, Caritra, Citroz, Fulcover, Fungixit, Intracan, Itaspor, Itcona, Itraconazole, Itracross, Itral, Itrasig, Itrole

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Also known as: Itraconazole

Description

{name} (itraconazole) is an antifungal medication that fights infections caused by fungus.

{name} is used to treat infections in adults caused by fungus, which can invade any part of the body including the lungs, mouth or throat, toenails, or fingernails.

It is not known if {name} is safe and effective in children.

Dosage

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Do not share Sporanox PulsePak with another person, even if they have the same symptoms you have.

The Sporanox PulsePak capsule should be taken with food.

Swallow the capsule whole and do not crush, chew, break, or open it.

Take Sporanox PulsePak oral solution (liquid) on an empty stomach, at least 1 hour before or 2 hours after a meal. Swish the liquid in your mouth for several seconds before swallowing it.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

The Sporanox PulsePak has a special dosing schedule that includes not taking the medicine for several days in a row. Follow all dosing instructions carefully.

Sporanox PulsePak capsules should not be used in place of itraconazole oral solution (liquid) if that is what your doctor has prescribed. Avoid medication errors by using only the form and strength your doctor prescribes.

If you also take a stomach acid reducer (Tagamet, Pepcid, Axid, Zantac, and others), take Sporanox PulsePak with an acidic drink such as non-diet cola.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Sporanox PulsePak will not treat a viral infection such as the flu or a common cold.

You may need frequent medical tests.

Store at room temperature away from moisture, heat, and light.

Detailed Sporanox dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Sporanox are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take this medicine if you are allergic to Sporanox PulsePak or similar medicines such as fluconazole or ketoconazole, or if you have ever had congestive heart failure.

Life-threatening side effects may occur if you take Sporanox PulsePak with certain other drugs. Your doctor may change your treatment plan if you have used other medicines in the past 2 weeks, especially:

avanafil; cisapride; eliglustat; irinotecan; isavuconazonium; methadone; naloxegol; ranolazine; ticagrelor; lurasidone or pimozide (anti-psychotic medications); lomitapide, lovastatin, simvastatin (cholesterol-lowering medicines); dihydroergotamine, ergonovine, ergotamine, or methylergonovine (ergot medicines); eplerenone, felodipine, ivabradine, or nisoldipine (heart or blood pressure medicines); disopyramide, dofetilide, dronedarone, or quinidine (medicines for heart rhythm disorders); or oral midazolam, or triazolam (Valium-like sedatives).

If you have liver or kidney disease, you should not take Sporanox PulsePak with colchicine, fesoterodine, solifenacin, or telithromycin.

Sporanox PulsePak may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 2 months after your last dose. Tell your doctor if you become pregnant.

Tell your doctor if you have ever had:

heart problems; cystic fibrosis or other lung problems; liver or kidney disease; or a weak immune system.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

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Pathogenesis, diagnosis and treatment of tuberculosis of the axillary zone. Spectral Characteristics of Si Quantum Dots Embedded in SiN(x) Thin Films Prepared by Magnetron Co-Sputtering. Multiple mechanisms responsible for strong Congo-red-binding variants of Escherichia coli O157:H7 strains. The frequencies of the B allele, with the BfaI site, were for 0.275, 0.775, 0.750, 0.975, respectively, for Italian Holstein Friesian, Grey Alpine, Friuli Red Pied and Reggio bovine breeds. Among the important issues remaining to be addressed are harmonizing and simplifying the various informed consent processes.

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Primary care implementation of integrated electronic medical records may have a beneficial effect on patient outcomes for diabetes and other chronic diseases. In this series, the results with stereotactic radiosurgery are discouraging compared with our results with conventional fractionated radiotherapy in patients with paraganglioma of the temporal bone. We show how this statistic may be used to automatically rank images of in vivo human tumors in order of increasing heterogeneity. Prostate specific antigen (PSA) based screening for PCa is controversial and large trials have failed to show a significant reduction in prostate-specific mortality and all-cause mortality. A comparison of complications and results in 400 cataract operations. High basal plasma levels of inflammatory molecules are associated with a higher risk of cardiovascular events.

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Mental Health and Functioning of Female Sex Workers in Chittagong, Bangladesh. Three regions on CNTF have been identified as binding sites for its receptors. Capsid protease domain as a tool for assessing protein-domain folding during organelle import of nascent polypeptides in living cells. We present the first case of a nonmetastasizing renal cell carcinoma (RCC) masquerading as an adrenal mass, in the presence of normal bilateral native kidneys, in a young adult. The combination of candesartan cilexetil and hydrochlorothiazide (AT(1)-receptor antagonist and thiazide diuretic, respectively) is an effective treatment for patients with hypertension. Two groups of MS patients with similar age and gender distributions received visual, motor and somatosensory EPs either during a relapse (Group 1) or in the relapse-free interval (Group 2). Then the tooth was selected as a target and its parameters of probing depth (PD), attachment loss (AL), BOP, gingival index (GI), plaque index (PI) and staining index (SI) were recorded. Even though the results of this survey must be interpreted with caution because of the limited response rate and possible sampling bias, they still reflect the current preferences and attitudes of North American surgeons toward prophylaxis. These children should undergo regular BMD evaluation, and an appropriate therapeutic approach should be planned.

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Influence of subthreshold nonlinearities on signal-to-noise ratio and timing precision for small signals in neurons: minimal model analysis. Gliadin- and immunoglobulin-containing cells of small intestinal lamina propria in childhood coeliac disease. Design and synthesis of the potent, orally available, brain-penetrable arylpyrazole class of neuropeptide Y5 receptor antagonists. Treated corneas were observed under the scanning electron microscope and immunohistologically. Low-dose co-treatment with naltrexone and bupropion produces a stronger suppression of appetite than that seen with either agent alone and has the additional advantage of reducing some of the unwanted effects of bupropion. A range of metabolites in the plasma, liver, kidney, and spleen of broiler chickens and plasma of piglets was changed following T-2 toxin injection. Thus, only the dephosphorylated form of cofilin associates with the actin cytoskeleton and possesses the capability to translocate into the nucleus. We show that lymphocyte trafficking is altered by the lysophospholipid sphingosine-1-phosphate (S1P) and by a phosphoryl metabolite of the immunosuppressive agent FTY720. The kinase domain expressed as a glutathione S-transferase fusion protein was capable of autophosphorylation, indicating that this gene encodes an active protein kinase. Despite their importance, misidentification at the species level is common for members of the genus Pediococcus.

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Antimutagenic action of cobaltous chloride on Trp-P-1-induced mutations in Salmonella typhimurium TA98 and TA1538. Pancreatic ductal adenocarcinoma (PDAC) presently has an incidence of approximately 8 to 10 cases per 100,000 citizens in European countries, and the incidence has been increasing throughout the last decades. Scaffold-free tissue engineering: organization of the tissue cytoskeleton and its how much is generic propecia effects on tissue shape. Evidently because of the constraint of similar cell numbers among the species, (nucleotypic) effects of nucleus size on cell size and on cell-level processes are expressed at the whole-organism level. Evaluation was undertaken using a previously validated pre- and post-survey tool, to ascertain changes in attitude among students towards interprofessional practice, IPE and the effectiveness of health care teams.

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In contrast, several elements expressing the S100beta protein, another astrocytic marker found to be located in distinct parts of the same cell when compared with glial fibrillary acidic protein, were also strongly immunoreactive for MCT1, suggesting expression of this transporter by astrocytes. The findings contribute to an understanding of sources of information and support preferred by adolescents. Detection of Candida albicans mannan by immunodiffusion, counterimmunoelectrophoresis, and enzyme-linked immunoassay. We describe a case of herpetic whitlow in a patient finishing 6 cycles of chemotherapy for refractory chronic lymphocytic leukemia that presented with a bilateral, multi-digit, crusted eruption of the hands. However, considering that the pharmacological target of statins, the 3-hydroxy-3-methyl-3-glutaryl coenzyme A (HMG-CoA) reductase, is one of the upstream enzyme of the mevalonate pathway, its inhibition may determine a substantial impoverishment of additional lipid moieties required for a proper cellular function. CMC vehicle increased the area under the concentration-time curve (AUC) of tilisolol in the tear fluid and aqueous humor and slightly reduced the AUC in plasma. Cadherins are cell-cell adhesion receptors that are essential for the establishment of the epithelial cell shape and maintenance of the differentiated epithelial phenotype. A double-labeling assay for detecting apoptotic cells, using the terminal deoxy-nucleotidyl transferase (TdT)-mediated dUTP nick end-labeling (TUNEL) assay, and antigens of interest, using immunofluorescence, is described.

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