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Nifedipress (Nifedipine)
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Nifedipress

Nifedipress is a dihydropyridine calcium channel blocker. Nifedipress is used to: treat high blood pressure (hypertension), prevent chronic stable angina (chest pain). Nifedipress was the first calcium channel blocker to be shown to significantly reduce the development of new overt heart failure in patients with coronary artery disease. Excellent blood-pressure control in recent clinical trials has been shown to result in significant protection against stroke. Nifedipress works by opening up blood vessels in the body to lower blood pressure and improve the supply of blood and oxygen to the heart. Calcium channel blockers do not change the amount of calcium in your blood or bones.

Other names for this medication:
Aprical, Calcianta, Cardalin, Cardules, Chronadalate, Conetrin, Cordalat, Cordilat, Corotrend, Depine, Duranifin, Emaberin, Farmalat, Fenamon, Ficard, Jutadilat, Marivolon, Nefelid, Nicardia, Nidipine, Nifebene, Nifecard, Nifeclair, Nifecor, Nifedigel, Nifedin, Nifedip, Nifedipina, Nifedipino, Nifin, Niften, Nipidin, Nirena, Noviken, Ospocard, Oxcord, Sepamit, Tensomax, Tensopin

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Also known as: Nifedipine

Description

Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Nifedipress PA 10. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Nifedipress and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Nifedipress are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Recurrence of kernicterus in term and near-term infants in Denmark. Using immunohistochemical analyses, a system L transporter LAT1 was shown to be expressed in the brain capillary endothelial cells in rats. In contrast, metergoline diminished the prolactin response to 5HTP. In the current study, structure-activity relationship (SAR) development towards a novel series of diarylthiophene analogues has continued through the use of substituted-benzene and -pyridyl moieties as bioisosteres for 2-thioxoimidazolidin-4-one (A) on a thiophene (B) -isobenzofuranone (C) scaffold. Ebselen (2-phenyl-1,2-benzisoselenazol-3(2H)-one, EbSe) was identified in a screen as a potent inhibitor of T. Mean SBS values obtained with the Swiss shear test were significantly lower than those obtained with the ISO shear test. Indeed, insufficient data about environmental and human safety assessments of migration and exposure of nanomaterials are hindering their market growth. The patient, who showed full clinical recovery within a few hours of symptom onset, received a short-term anticoagulant treatment followed by aspirin for long-term prevention.

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Chronic renal failure is associated with a 20-fold increased risk of cardiovascular mortality, in part due to accelerated atherosclerosis. The product pattern as well as the transformation pathway of N-(2-hexylamino-4-phenylimidazol-1-yl)-acetamide differed in the various strains used. A double-blind crossover trial comparing human insulin (recombinant DNA) with animal insulins in the treatment of previously insulin-treated diabetic patients. Schistosoma japonicum egg specific protein SjE16.7 recruits neutrophils and induces inflammatory hepatic granuloma initiation. We have stretched a small piece of poly(ethylene glycol) (PEG) in water at finite temperature. Asthma and related symptoms were common among Malay school children in inner city Kuala Lumpur. Blood cadmium concentration in the population of the Rabat area, Morocco. The Drosophila larva has turned out to satisfy these demands based on the availability of robust behavioral assays, the existence of a variety of transgenic techniques and the elementary organization of the nervous system comprising only about 10,000 neurons (albeit with some concessions: cognitive limitations, few behavioral options, and richness of experience questionable). Simple analgesics or nonsteroidal anti-inflammatory drugs, with or without antiemetics, are usually the first line of treatment and are effective for some attacks.

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Ethanolic extracts of Euphorbia and other ethnobotanical species as inhibitors of human tumour cell growth. These findings add to existing literature by indicating that impairments in inhibitory behavior during adolescence do not reflect an inability to learn to inhibit a response, but instead reflect a specific deficit in expressing that learning. Association between single nucleotide polymorphism rs342286 near the PIK3CG gene and acute coronary syndromes. To examine the relationships between linguistic deviations and symptoms in patients with acute psychosis. Cognitive precursors of arithmetic development in primary school children with cerebral palsy. To evaluate the changes in health-related quality of life in unilateral adult cochlear implant patients using the Medical Outcome Study Short-Form Survey-36 (SF-36) and the Health Utility Index Mark 3 (HUI-3). For the women, data were collected during each trimester of pregnancy and at 3, 6, 12, 24, and 36months after the birth of their infant.

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Administration of di-n-propylacetate (DPA), an inhibitor of SSA-dehydrogenase, produces in naive rats abstinence behaviour which can be blocked by morphine and bicuculline and may be useful as a behavioural correlate of increased GABA-ergic activity. Our Z(-/-/-)/Z-HA cell line would be useful for evaluating proteolytic processes catalyzed by the proteasome in many biological events in vertebrate cells. The clinical correlations between the digestive and circulatory systems. Iatrogenic atrial septal defects following atrial fibrillation transcatheter ablation: a relevant entity?. Ethnic differences in survival among women with ovarian carcinoma. Stent implantation to the stenosed right coronary artery in a patient whose right and left coronary arteries originate from a single ostium in the right sinus of Valsalva. Recent developments in health insurance, life insurance, and disability insurance case law. Epithelial thickness was assessed at 21 points, 0.5 mm apart, across the central 6-mm of the corneal apex in the horizontal and vertical meridians. Advancement of a conjunctival flap with preservation the preexisting bleb often provides successful resolution of bleb-associated complications.

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Long-term weight loss was associated with a larger increase in dietary restraint and larger decrease in disinhibition. Although percutaneous coronary intervention (PCI) significantly decreases mortality after myocardial infarction, the evidence is less convincing for intra-aortic balloon counterpulsation. Accelerated program of dental education in World War II: what have we learned from it?. Here we show that activation of IRF-7, like that of IRF-3, is dependent on modifications of two distinct sets of Ser/Thr residues. To study the efficacy of infrared diode laser for the treatment of posterior retinopathy of prematurity (ROP). Basal levels of TrkA and TrkC in primary CFs are comparable to those in cardiomyocytes. Anecdotal reports suggest hypnosis might be a useful treatment, leading to reductions in distress and improvements in the condition. Urea and creatinine behaved similarly in the saline and mannitol experiments, but rose above control values within 1 hour of dextrose replacement. Uterine fibroid embolization without the use of iodinated contrast material.

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Still a Long Way to Go for Anterior or Extensive Chest Wall Reconstruction. Participants discussed tradeoffs regarding the perceived benefits and risks of weight gain, often with uncertainty and inadequate information regarding the short- and long-term consequences. Stem cell grafting for epilepsy: clinical promise and ethical concerns. Maternal serum levels of neutrophil gelatinase-associated lipocalin (NGAL), matrix metalloproteinase-9 (MMP-9) and their complex MMP-9/NGAL in pregnancies with preeclampsia and those with a small for gestational age neonate: a longitudinal study. Antismoking efforts often target teenagers in the hope of producing a new generation of never smokers. Ultrasound-assisted emulsification microextraction combined with ultra-high performance liquid chromatography-tandem mass spectrometry for the analysis of ibuprofen and its metabolites in human urine. Utilization of a method of growing microorganisms on millipore filters in order to study their structure with a scanning electron microscope. We also map the lattice model onto a continuum DFT that facilitates a simplification of the stability analysis of the uniform fluid.

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A stereophotogrammetric image of the mask and a 3D spiral CT image of the model head were captured. These results suggest that TNFalpha could be involved in the pathogenesis of EAO. Successive petroleum ether, chloroform, ethanol and water extracts, a saponin rich fraction (SRF) and bacoside A isolated from Bacopa monnieri were tested for brine shrimp lethality. Further observations concerning the action of pituitary thyrotropin on the intermediate metabolism of sheep thyroid tissue in vitro. Local, regional, distant, and allograft tendon can be used to supplement or enhance sumycin 500 mg uses in hindi reconstruction or repair of the Achilles tendon. Results of a double-blind crossover study in type I diabetic patients with continuous subcutaneous insulin infusion. CHMP4C Disruption Sensitizes the Human Lung Cancer Cells to Irradiation. Evidence is presented suggesting the presence of galactosyl transferases and galactosyl acceptors on the outer surfaces of intact Balb/c 3T3 cells.

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Livestock grazing management directly influences both economic outputs and biodiversity on upland farms while contributing to potentially damaging greenhouse gas emissions, yet no study has attempted to address these impacts simultaneously. Coupling the spin degree of freedom to the anisotropic orbital motion of two-dimensional (2D) hole systems gives rise to a highly anisotropic Zeeman splitting with respect to different orientations of an in-plane magnetic field B relative to the crystal axes. 2-Methylindole as an indicative nucleophile for developing a three-component reaction of aldehyde with two different nucleophiles. Reduction in monocyte chemoattractant protein-1 mRNA expression in peripheral blood mononuclear cells of diamorphine addicts. square penetrating keratoplasty using a locally can i take neurontin with drink alcohol designed souble bladed knife for total anterior staphylomata. Expression of heat shock proteins in osteosarcoma and its relationship to prognosis. C-reactive protein in newborn infants born at term with signs of intrauterine dystrophy. Patients with T2D who receive DPP4-I could achieve almost similar glycaemic targets with sulphonylureas, with favourable effects on body weight and lower incidence of hypoglycaemia. Our results show a high prevalence of rubber glove-induced dermatoses among the employees in one Italian hospital. Genetic regulation of delayed-type hypersensitivity responses to poly(LTyr,LGlu)-poly(DLAla)--poly(LLys).

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