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Nidipine (Nifedipine)

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Nidipine is a calcium-channel blocker. It affects the amount of calcium found in your heart and muscle cells. This relaxes your blood vessels, which can reduce the amount of work the heart has to do. This medicine is used to treat chest pain caused by angina.

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Nidipine PA 20. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Nidipine and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Nidipine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of nifedipine in the pediatric population. Safety and efficacy have not been established.

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Identifying the target population in an effective and efficient manner remains a challenge for health plans. Over the next several weeks, additional neurologic deficits developed and continued to progress despite various treatment interventions. A curative treatment option for Complex Regional Pain Syndrome (CRPS) Type I: dorsal root entry zone operation (report of two cases). Positive effect of amoxicillin/clavulanic acid for exacerbations of mild to moderate copd. Great care is required of clinicians to reach an early diagnosis in order to promote adequate management and prevent inherently severe complications. Origin of sucrose metabolism in higher plants: when, how and why?. Cancer mortality in a cohort of male German iron foundry workers. Type 1 PDZ domains usually require valine, leucine, or isoleucine at the very COOH-terminal (P(0)) position, and serine or threonine 2 residues upstream at P(-2). Tissue Doppler echocardiography (TDE) is a promising method for the assessment of regional myocardial function, but pulsed TDE does not provide quantitative data from multiple regions simultaneously. Spheroplast L-form of borrelia could be responsible for difficulties with their eradication.

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The CENP-L-N Complex Forms a Critical Node in an Integrated Meshwork of Interactions at the Centromere-Kinetochore Interface. Selective intracoronary thrombolysis in acute myocardial infarction and unstable angina pectoris. Parasitological examinations (skin sniping and nodule palpation) were done on eligible candidates. Metformin has been shown to produce small but significant reductions in BMI. Lethal Giant Larvae (LGL) is a cytosolic cell polarity scaffold whose loss dominantly enhances neuromuscular junction (NMJ) synaptic overgrowth caused by loss of the Fragile X Mental Retardation Protein (FMRP). Vaccines often have heterogeneous actions because of possible variation in the immune systems of hosts. Cellular and molecular engineering of yeast Saccharomyces cerevisiae for advanced biobutanol production.

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The selectins bind weakly to sialyl Lewisx (SLe(X))-like glycans, but with high-affinity to specific glycoprotein counterreceptors, including PSGL-1. To compare the effect of ablations with pulsed and continuous high-intensity focused ultrasound (HIFU) on the target area containing large blood vessels in isolated perfused porcine liver. Failure of tubule fluid osmolarity to affect feedback regulation of glomerular filtration. Aberrant regulation of the Wnt pathway, essential for various developmental processes, is tightly linked to human breast cancers. Incorporating animal spatial memory in step selection functions. When incubated with mast cells alone, only anandamide could induce significant level of histamine release at concentrations higher than 10(-6) M. The APC/C activator FZR1 is essential for meiotic prophase I in mice. The structured cooperation between the health sector that has to inform the participants and the sports sector that provides the wide network of standardised programmes is the strength of the study, but at the same time a challenge. Feedback from families has demonstrated positive support for this format.

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After mid-term follow-up, the strategy of ablating FIRM-identified rotors alone did not prevent recurrence from AT/AF. The association of these findings, although non specific, can be observed in all the different forms of NCL, narrows the differential diagnosis of the infantile progressive encephalopathies and may suggest the diagnosis. Thus, ectopic Wnt expression is able to override the influence of ventralizing signals arising from notochord and floor plate. Pretreatment did not consistently produce a better result than treatment started after infection. N-acetylcysteine modulates hallucinogenic 5-HT(2A) receptor agonist-mediated responses: behavioral, molecular, and electrophysiological studies. Appearance of new N-terminal residues upon treatment of human and bovine serum albumin with N-bromosuccinimide. Assessment of antibody-independent cellular cytotoxicity (AICC) of porcine neutrophilic granulocytes by quantitative flow cytometry. The changed patterns in pneumococcal carriage after PCV vaccination predicted by the model are unequivocal. Non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors: past, present, and future perspectives.

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The preventive effects of various doses of the immunomodulator P40 on the experimental E. Interestingly, inhibition of apoptosis with a caspase 3 inhibitor also reduced some of the maturation induced by exposure to ALVAC. Healthcare needs of people with intellectual disability in institutions in Taiwan: outpatient care utilization and implications. This study aimed to describe the strategies proposed by the first institutions to receive CTSA funding and to undergo the CTSA renewal process. Over a 25-year period, unusual cases involving the musculoskeletal, genitourinary, cardiopulmonary, and gastrointestinal systems have been encountered. Treatment was given three times weekly until complete clearing or to a maximum of 8 weeks. Activation increased in the right striatum, right ventral and dorsal inferior frontal gyrus, and supplementary motor area. Cerebrospinal fluid analysis was normal in the majority of dogs.

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To investigate the relation of electrolytes(NaCl, Na2SO4) to the by-product CHCl3 produced in the electrochemical disinfection process. A 12-month-old boy with pulmonary tuberculosis developed a papular lichenoid eruption which showed epithelioid granulomas on histology, consistent with lichen scrofulosorum. The mean scores of gastric mucosa with mild, moderate and severe cozaar medication generic degrees of H. The aim of this review was to correlate the preoperative clinical diagnoses and the diagnostic arthroscopic findings in preadolescents with knee problems. The benefits of new immunosuppressive treatments in adult kidney transplantation. Alphabetical inventory of sanitary equipment of a sanitary company with data on classification and location in the chests.

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They struggle with the interface between career demands and personal life. Trunk movements and nonbiological stimuli did not significantly elicit similar reactions. Part 1: T-cell and natural killer/t-cell lymphomas and related conditions. Children with colic had maternal ratings suggestive of more difficulty with emotional regulation than their noncolic matches and displayed a more impulsive cognitive style. Sequence and phylogenetic analysis of these strains revealed that they shared what mg does benicar come in molecular features with the pandemic H1N1 influenza virus strains, which emerged globally during 2009. In normal controls sequence learning was associated with activations in the right prefrontal, premotor, parietal, rostral supplementary motor area, and precuneus regions. Toxoplasma gondii migration within and infection of human retina. Proflavine inhibition of protein synthesis in malignant hamster melanoma. Occurrence, composition, and structure of mitochondrial crystals in a hypotrichous ciliate.

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Behavior of blood coagulation and tendency toward thrombosis in certain internal diseases. The etiology of urinary tract infection: traditional and emerging pathogens. Feasibility of proximal right coronary artery imaging by 2D and 3D echocardiography in comparison to coronary angiography. The generation of glutamate correlated with stimulated mitochondrial activity monitored as oxygen consumption and was inhibited by the mitochondrial uncoupler carbonyl cyanide p-trifluoromethoxyphenylhydrazone. The described method is sensitive over a wide range of product concentrations and offers good reproducibility. Control experiments with 6-hydroxydopamine and the catecholamine uptake blocker, nomifensine, indicate that this loading is specific for catecholamine systems. Fluocinolone acetonide 0.2 per cent cream--a co-operative clinical trial. Gene regulation by steroid hormone receptors depends on the particular character of the DNA response element, the array of neighboring transcription factors, and recruitment of coactivators that interface with the transcriptional machinery.

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Programming of more lean tissue rather than fat mass by a high birth weight might explain this paradox and also explain the association of birth weight with later body mass index. Diagnosis of compensated hypovolemic shock (compensated acute hypovolemia). This article describes the guideline development process and associated concerns and the advances in the field of CPGs. The nucleotide sequence of the 554-bp control region DNA and adjacent portions of the malX and malM structural genes was determined. The metabolites to be found seem to reflect a derepression of a genotypical synthesis program, which is not phenotypically apparent in healthy adults, but which may have been active during prenatal developmental stages of the liver. A major fraction of budesonide is released in the ileum and throughout the colon, the intended target for the controlled-release formulation. In this study, we have zantac 75 mg dosage explored these potential associations and hypothesized that ET would be associated with greater overall WMH volume, greater cerebellar WMH volume, and greater infarct presence.

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Quantification of the organophosphorus nerve agent soman by competitive inhibition enzyme immunoassay using monoclonal antibody. Preparation of bovine mercaptalbumin by means of covalent chromatography. Multiple births, preterm births and a higher overall rate of fetal anomalies were found in California after ART/AI for 2009-2011. An explanation of this phenomenon is given in terms of the combined effects of diffusion and convection and in terms of data consistent with the hypothesis. Data on special features of transmission of the 1BL/1RS translocation through male and female gametes are presented.

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