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Nexium (Esomeprazole)

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Nexium is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Nexium is also used to promote healing of erosive esophagitis.

Other names for this medication:
Epraz, Esgred, Esodoc, Esofag, Esofine, Esomac, Esomeprazole, Esomper, Esoper, Esotrax, Ignis, Naksium, Neutraflux, Nexpro, Prazonid, Raciper, Ranidom, Sompraz

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Also known as: Esomeprazole


{name} (esomeprazole magnesium) is a proton pump inhibitor that decreases the amount of acid produced in the stomach.

{name} is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. It is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).

{name} may also be given to prevent gastric ulcer caused by infection with Helicobacter pylori (H. pylori), or by the use of nonsteroidal anti-inflammatory drugs (NSAIDs).

{name} is not for immediate relief of heartburn symptoms.


Use Nexium exactly as directed on the label, or as prescribed by your doctor.

Take each dose with a full glass (8 ounces) of water.

Nexium should be taken at least one hour before a meal.

Do not crush or chew a delayed-release capsule. However to make swallowing easier, you may open the capsule and sprinkle the medicine into a spoonful of pudding or applesauce. Swallow right away without chewing. Do not save the mixture for later use.

The capsule can be given through a nasogastric (NG) feeding tube. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Esomeprazole is usually given for 4 to 8 weeks only. Your doctor may recommend a second course of treatment if you need additional healing time.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve.

Call your doctor if your symptoms do not improve or if they get worse while you are taking this medicine.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using esomeprazole.

Some conditions are treated with a combination of esomeprazole and antibiotics. Use all medications as directed.

Store at room temperature away from moisture and heat.

Detailed Nexium dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Nexium are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Nexium I.V. if:

you also take medicine that contains rilpivirine (Edurant, Complera, Juluca, Odefsey); you had breathing problems, kidney problems, or a severe allergic reaction after taking esomeprazole in the past; or you are allergic to esomeprazole or similar medicines (lansoprazole, omeprazole, Nexium, Prevacid, Prilosec, and others).

Many drugs can interact and cause dangerous effects. Some drugs should not be used together with esomeprazole. Your doctor may change your treatment plan if you also use:

clopidogrel; methotrexate (at high doses); rifampin; St. John's wort; or medicine that contains rilpivirine (such as Complera, Edurant, Juluca, or Odefsey).

To make sure Nexium I.V. is safe for you, tell your doctor if you have ever had:

severe liver disease; lupus; osteoporosis or low bone mineral density (osteopenia); or low levels of magnesium in your blood.

Heartburn can mimic early symptoms of a heart attack. Get emergency medical help if you have chest pain that spreads to your jaw or shoulder and you feel anxious or light-headed.

You may be more likely to have a broken bone in your hip, wrist, or spine while taking a proton pump inhibitor long-term or more than once per day. Talk with your doctor about ways to keep your bones healthy.

It is not known whether esomeprazole sodium will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed while using Nexium injection. Ask your doctor about any risk.

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