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Naprosyn (Naproxen)

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Naprosyn is the longest-lasting over-the-counter non-steroidal anti-inflammatory drug (NSAID) currently available, but there are prescription anti-inflammatory medications that last longer than this medication. Naprosyn isn't necessarily stronger than other NSAIDs, but many people find it provides relief longer.

Other names for this medication:
Aleve, Anaprox, Artagen, Arthopan, Movibon, Naprelan, Naprodom, Naproxen, Naxdom, Pacinac, Xenadom, Xenar, Xenobid

Similar Products:
Noroxin, Mobic, Cardizem, Biaxin, Crestor, Propecia

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Also known as: Naproxen


Naprosyn is a drug which helps to fight with arthritis, menstrual cramps, tendinitis, bursitis, osteoarthritis, rheumatoid arthritis, juvenile arthritis, gouty arthritis, ankylosing spondylitis and its symptoms (inflammation, fever, pain and other). Naprosyn belongs to the group of drugs called NSAIDs (nonsteroidal anti-inflammatory drugs). Naprosyn is also known as Aleve, Naprelan, Naprogesic. Naprosyn works by decreasing hormones caused pain and inflammation. Naprosyn can't be taken by children under 2 years.


This section provides information on the proper use of a number of products that contain naproxen. It may not be specific to EC Naprosyn. Please read with care.

For safe and effective use of this medicine, do not take more of it, do not take it more often, and do not take it for a longer time than ordered by your doctor. Taking too much of this medicine may increase the chance of unwanted effects, especially in elderly patients.

This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

When used for severe or continuing arthritis, this medicine must be taken regularly as ordered by your doctor in order for it to help you. This medicine usually begins to work within one week, but in severe cases up to two weeks or even longer may pass before you begin to feel better. Also, several weeks may pass before you feel the full effects of this medicine.

Check with your doctor first before changing dosage forms (eg, tablets, suspension). These forms are very different from each other.

Swallow the delayed-release tablet whole. Do not crush, break, or chew it.

If you are using the suspension, shake it gently before using it. Use the marked measuring cup included in the package to measure the dose.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For naproxen (eg, Naprosyn®) tablet and oral suspension dosage forms: For rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis: Adults—At first, 250 milligrams (mg) (10 milliliters (mL)/2 teaspoonfuls), 375 mg (15 mL/3 teaspoonfuls), or 500 mg (20 mL/4 teaspoonfuls) 2 times a day, in the morning and evening. Your doctor may adjust your dose as needed. However the dose is usually not more than 1500 mg per day. Children 2 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 milligrams (mg) per kilogram (kg) of body weight 2 times a day. Children younger than 2 years of age—Use and dose must be determined by your doctor. For acute gout: Adults—750 milligrams (mg) for the first dose, then 250 mg every 8 hours until the attack is relieved. Children—Use and dose must be determined by your doctor. For naproxen controlled-release tablet (eg, Naprelan®) dosage form: For rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis: Adults—At first, 750 milligrams (mg) (taken as one 750 mg or two 375 mg tablets) or 1000 mg (taken as two 500 mg tablets) once a day. Your doctor may adjust your dose as needed. However the dose is usually not more than 1500 mg (taken as two 750 mg or three 500 mg tablets) per day. Children—Use and dose must be determined by your doctor. For bursitis, tendinitis, menstrual cramps, and other kinds of pain: Adults—At first, 1000 milligrams (mg) (taken as two 500 mg tablets) once a day. Some patients may need 1500 mg (taken as two 750 mg or three 500 mg tablets) per day, for a limited period. However, the dose is usually not more than 1000 mg per day. Children—Use and dose must be determined by your doctor. For acute gout: Adults—1000 to 1500 milligrams (mg) (taken as two to three 500 mg tablets) once a day for the first dose, then 1000 mg (taken as two 500 mg tablets) once a day until the attack is relieved. Children—Use and dose must be determined by your doctor. For naproxen delayed-release tablet (eg, EC-Naprosyn®) dosage form: For rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis: Adults—At first, 375 or 500 milligrams (mg) 2 times a day, in the morning and evening. Your doctor may adjust the dose as needed. However, the dose is usually not more than 1500 mg per day. Children—Use and dose must be determined by your doctor. For naproxen sodium (eg, Anaprox®, Anaprox® DS) tablet dosage form: For rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis: Adults—At first, 275 or 550 milligrams (mg) 2 times a day, in the morning and evening. Your doctor may adjust the dose as needed. However, the dose is usually not more than 1500 mg per day. Children—Use and dose must be determined by your doctor. For bursitis, tendinitis, menstrual cramps, and other kinds of pain: Adults—550 milligrams (mg) for the first dose, then 550 mg every 12 hours or 275 mg every 6 to 8 hours as needed. Your doctor may adjust the dose as needed. However, the dose is usually not more than 1375 mg per day. Children—Use and dose must be determined by your doctor. For acute gout: Adults—825 milligrams (mg) for the first dose, then 275 mg every 8 hours until the attack is relieved. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed EC-Naprosyn dosage information

Side effects

The most common side effects associated with Naprosyn are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Naprosyn if you are allergic to Naprosyn components. Be careful with Naprosyn if you are pregnant, planning to become pregnant, or are breast-feeding. Naprosyn can pass into breast milk. Naprosyn can harm your baby. Do not take Naprosyn before or after heart bypass surgery (CABG). Be careful with Naprosyn if you are taking blood thinner (such as warfarin (Coumadin)); diuretics (such as furosemide (Lasix)); lithium (such as Lithobid, Eskalith); steroids (such as prednisone); aspirin or other NSAIDs (ketoprofen (such as Orudis), indomethacin (such as Indocin), diclofenac (such as Voltaren), etodolac (such as Lodine), naproxen (such as Naprosyn, Aleve), ibuprofen (such as Motrin, Advil); glyburide (such as DiaBeta, Micronase); cyclosporine (such as Sandimmune, Gengraf, Neoral); ACE inhibitor (enalapril (such as Vasotec), fosinopril (such as Monopril), benazepril (such as Lotensin), quinapril (such as Accupril), captopril (such as Capoten), trandolapril (such as Mavik), lisinopril (such as Zestril, Prinivil), ramipril (such as Altace), moexipril (such as Univasc), perindopril (such as Aceon); methotrexate (such as Trexall, Rheumatrex). Elderly people should be careful with dosage of Naprosyn. Be very careful with Naprosyn if you suffer from or have a history of heart, kidney or liver disease, asthma, bowel problems, nose polyps, diverticulosis, stomach ulcers, bleeding, blood clot, high blood pressure, stroke, congestive heart failure. Avoid smoking while taking Naprosyn. Avoid consuming alcohol. Avoid taking aspirin if you are taking Naprosyn. Protect your skin from the sun. Be careful with Naprosyn if you are going to have a surgery (dental or other). Naprosyn can't be taken by children under 2 years. It can be dangerous to stop Naprosyn taking suddenly.

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Towards eliminating lymphatic filariasis in Papua New Guinea: impact of annual single-dose mass treatment on transmission of Wuchereria bancrofti in East Sepik Province. Owing to the low penetration depth (1 mm) and high resolution (10 microm), OCT images may become comparable to mucosal histological findings. Participants with venous leg ulcers will receive either 150 mg aspirin or placebo daily for up to 24 weeks. Even though hamstring autografts and tibialis allografts provided good functional outcomes without significant differences, the second-look arthroscopy revealed that hamstring autografts produced better synovial coverage than tibialis allograft. Discharge patterns are correlated with distinctive current-voltage relationships and with some aspects of dendritic morphology. Pharmacoeconomic implications of thromboprophylaxis with new oral anticoagulants after total hip or knee replacement in the USA. Orthopaedic impairment, such as lower extremity weakness and swelling, also has been described in association with sacrococcygeal teratomas. The cell cycle must be involved in cell proliferation of the epithelium of middle ear cholesteatoma Cyclins and cyclin-dependent kinase (CDK) complexes have important regulatory roles during cell cycle progression.

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The construct was introduced into a pig cell line by yeast-mammalian cell fusion and G418 resistant clones were obtained. Simplification of the assay clobetasol gel reviews of enzymes using non-linear reaction-progress graphs. These results show testing of BAT-26 alterations is a convenient and rapid screening method for identifying a subset of gastric cancer with a mutator phenotype and better prognosis. At the late stage, finally, deep immunosuppression allows emerging of the atypical mycobacteries. State of the art and outlook for the development of physical therapy equipment. The immature-to-total neutrophil ratio (IT ratio) is a sensitive indicator of sepsis after paediatric cardiopulmonary bypass.

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Azathioprine administration to NZB X NZW hybrid mice with lupus nephritis: beneficial effect complicated by development of malignant lymphomas. Tumor invasion to the subserosal or serosa layer was regarded as invasion to the adventitia for E7 staging. This is a report of a new method for surgical thymectomy using the robotic da Vinci surgical system for a totally endoscopic approach. Multiregression showed association between end and basal score, on the one hand, and a better result in males and shorter tremor duration, on the other. Macrophage viability was measured by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assays.

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In yeast, at least five genes are involved: RAD9, RAD17, RAD24, RAD53 and MEC1, a homologue of ATM. A study of the views of African and Indian patients in a Durban hospital. The TH-positive axons are arranged in groups and are located in the endoneurium. Furthermore, localization of poliota in replication foci is largely dependent on the presence of poleta. It is proposed that the spin-projected particle numbers can distinguish the quantum spin Hall state from other states, and can be used to establish a new topological index for the system. In this article, the authors attempt to simplify the approach to both upper and lower lid blepharoplasty and provide an algorithm based on the individual findings for any given patient. Patients with lesions in anterior, medial, and/or subcortical lesions showed significantly lower SEEKING scores and higher depression scores than nonlesioned subjects in the control group. Children of mothers with hypertension in pregnancy plus diuretic treatment in the third trimester were zebeta pill at significantly increased risk of developing schizophrenia.

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