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Myambutol (Ethambutol)
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Myambutol

Myambutol (generic name: ethambutol; brand names include: EMB / Etibi / Combutol / Mycobutol / Tibitol / Servambutol / Tibinil) belongs to a group of medicines called antitubercular agents. Myambutol is used for the treatment of pulmonary tuberculosis, usually in combination with other antituberculosis medicines.

Other names for this medication:
Althocin, Amiobutols, Bacbutol, Combutol, Corsabutol, Dexambutol, Ebutol, Esanbutol, Etambutol, Etapiam, Etham, Ethambutol, Ethambutolo, Ethambutolum, Etibi, Fiambutol, Macox, Miambutol, Mycobutol, Niazitol, Oributol, Pulna, Rifafour, Rimstar, Santibi, Sural, Themibutol, Tibitol, Tibutol, Turresis

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Also known as: Ethambutol

Description

Myambutol is a prescription medication used for the treatment of pulmonary tuberculosis. It is usually given in combination with other tuberculosis drugs, such as isoniazid, rifampicin and pyrazinamide.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Dosage

Initial Treatment: In patients who have not received previous antituberculous therapy, administer Myambutol 15 mg/kg (7 mg/ lb) of body weight, as a single oral dose once every 24 hours. In the more recent studies, isoniazid has been administered concurrently in a single, daily, oral dose.

Retreatment: In patients who have received previous antituberculous therapy, administer Myambutol 25 mg/kg (11 mg/lb) of body weight, as a single oral dose once every 24 hours. Concurrently administer at least one other antituberculous drug to which the organisms have been demonstrated to be susceptible by appropriate in-vitro tests. Suitable drugs usually consist of those not previously used in the treatment of the patient. After 60 days of Myambutol administration, decrease the dose to 15 mg/kg (7mg/ lb) of body weight, and administer as a single oral dose once every 24 hours.

During the period when a patient is on a daily dose of 25 mg/kg, monthly eye examinations are advised.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store Myambutol at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Myambutol out of the reach of children and away from pets.

Side effects

The most common side effects associated with Myambutol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Myambutol if you are allergic to it. You may not be able to take this medicine if you have an eye condition called optic neuritis (inflammation of nerve fibers behind your eyes). Your doctor will decide if this treatment is right for if you have an eye disorder.

Myambutol can cause vision problems that may be a sign that you should stop taking the medicine. You may not be able to take this medicine if you cannot recognize or report any changes in your vision. Young children or debilitated patients may not be able to tell someone about vision problems.

To make sure Myambutol is safe for you, tell your doctor if you have:

inflammatory eye disorders such as uveitis or iritis; eye problems caused by diabetes; cataracts; liver disease; kidney disease; or gout.

FDA pregnancy category C. It is not known whether Myambutol will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

Ethambutol can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Myambutol should not be given to a child younger than 13 years old.

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Hybridization studies of fibroblasts from Hurler, Scheie, and Hurler/Scheie compound patients: support for the hypothesis of allelic mutants. Defects in the neuroendocrine-immune interactions can profoundly affect the susceptibility to developing chronic inflammatory disease and influencing survival after bacterial infections. Hypothyroidism in premenopausal females does not have any influence on bone density. A single GNAS1 mutation may be responsible for both PHP-Ia and PPHP in the same family when inherited from the maternal and the paternal allele, respectively, suggesting that GNAS1 is an imprinted gene. Cerebral air embolism after central venous catheter self-extraction. Meta-Analysis of Radial Versus Femoral Access for Percutaneous Coronary Interventions in Non-ST-Segment Elevation Acute Coronary Syndrome.

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Analysis of the tubuloglomerular feedback mechanism in renal autoregulation. Correlation of auxotype and penicillin susceptibility of Neisseria gonorrhoeae with sexual preference and clinical manifestations of gonorrhea. Amino acid analysis demonstrates the presence of phosphoserine within Arix. Biochemical and electrophysiological differentiation profile of a human neuroblastoma (IMR-32) cell line. When denervated teeth are injured, either by pulp exposure on the occlusal surface or by replantation, they have more pulpal necrosis than occurs for innervated teeth.

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In the current study we assessed the contribution of humoral and cellular immune responses to heterosubtypic protection against H5N1 induced by a Matrix-M (MM) adjuvanted seasonal influenza vaccine by serum transfer and T-cell depletion studies. An anchored AFLP- and retrotransposon-based map of diploid Avena. Through the dramatic radiographic images this case serves actos medication 30mg as a reminder to clinicians to obtain imaging of patients with a new or existing diagnosis of malignancy, who show symptoms of skeletal pain, as lesions requiring emergency management may be present. To assess complement-mediated myocardial injury on isolated guinea pig working hearts and cardioprotective effects of CD59. The Andersen sampler gave the highest bacterial counts in all environments tested. In two experiments, we measured whether the causal linkage of information would be generally protective against all memory errors or only selectively protective against certain types of memory errors. Serum cartilage-derived retinoic acid-sensitive protein (CD-RAP) levels in swarm rat chondrosarcoma. Indices of vascular endothelial dysfunction in LC can be of diagnostic and prognostic value. An uncommon cause of bifacial weakness and non-length-dependent demyelinating neuropathy. These guidelines, which were approved by the membership at the general meeting of the 9th International Conference of the W.A.A.V.P.

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Effect of Target Length on Specificity and Sensitivity of Oligonucleotide Microarrays: A Comparison between Dendrimer and Modified PCR based Labelling Methods. His postoperative pulmonary function was maintained in good condition despite a gradual slight decrease 2 years after LVRS. Gradient fractionation experiments showed that Mnn9p and the retrograde v-SNARE, Sec22p, were incorporated into COPI-coated vesicles. This paper reports the results of a systematic review of 20 empirical intervention studies on eating disorders prevention, discussing the data accumulated on what has and has not been effective. The aim of this study is to summarize recent findings regarding the relationship between CXCL12 and MS. Necrotizing soft tissue infections are a group of diseases with significant associated mortality.

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