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Imitrex (Sumatriptan)

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Imitrex is used to treat the symptoms of migraine headaches (severe, throbbing headaches that sometimes are accompanied by nausea or sensitivity to sound and light). Imitrex is in a class of medications called selective serotonin receptor agonists.

Other names for this medication:
Migratan, Sumatriptan, Suminat, Sumitrex

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Also known as: Sumatriptan


Sumatriptan is used to treat acute migraine headaches in adults. It is not used to prevent migraine headaches and is not used for cluster headaches. Sumatriptan works in the brain to relieve the pain from migraine headaches. It belongs to the group of medicines called triptans.

Many people find that their headaches go away completely after they take sumatriptan. Other people find that their headaches are much less painful, and that they are able to go back to their normal activities even though their headaches are not completely gone. Sumatriptan often relieves other symptoms that occur together with a migraine headache, such as nausea, vomiting, sensitivity to light, and sensitivity to sound.

Sumatriptan is not an ordinary pain reliever. It will not relieve pain other than from migraine headaches. This medicine is usually used for people whose headaches are not relieved by acetaminophen, aspirin, or other pain relievers.

Sumatriptan has caused serious side effects in some people, especially people who have heart or blood vessel disease. Be sure that you discuss with your doctor the risks of using this medicine as well as the benefits that it can have.

This medicine is available only with your doctor's prescription.


Use sumatriptan as soon as you notice headache symptoms. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Never use more than your recommended dose. Overuse of migraine headache medicine can make headaches worse. Tell your doctor if the medicine seems to stop working as well in treating your migraine attacks.

Sumatriptan is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself.

This medicine comes in a vial (bottle), a needle-free injector device, or a prefilled cartridge for an auto-injector syringe. Each type is for one use only.

Read and carefully follow any Instructions for Use provided with your medicine. Do not use sumatriptan if you don't understand all instructions for proper use. Ask your doctor or pharmacist if you have questions.

Prepare your injection only when you are ready to give it. Do not use a vial if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine.

After an injection: If your headache does not completely go away, call your doctor before using a second injection. If your headache goes away and then comes back, use a second injection if it has been at least 1 hour since your first injection. Do not use more than 2 injections in 24 hours. Call your doctor if your symptoms do not improve.

Store at room temperature away from moisture, heat, and light. Throw away any unused medicine after the expiration date on the label has passed.

Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.

Detailed Imitrex dosage information


If you overdose Imitrex and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Imitrex overdosage: breathing problems, blue-colored lips or fingernails, weakness, lack of coordination, shaking, convulsions, vision problems, skin redness, watery eyes or mouth.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Throw away used syringes or autoinjectors in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

Detailed Imitrex dosage information

Side effects

The most common side effects associated with Imitrex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Imitrex if you are allergic to Imitrex components or to aspirin. Do not take Imitrex if you are pregnant, planning to become pregnant. Avoid breast-feeding. Be careful with this medicine if you smoke, if you are postmenopausal, or if you are a man over 40. Be careful using Imitrex if you take selective serotonin reuptake inhibitors (Ssris) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, in symbyax), fluvoxamine, paroxetine (Paxil), and sertraline (Zoloft); and selective serotonin/norepinephrine reuptake inhibitors (Snris) such as duloxetine (Cymbalta) and venlafaxine (Effexor). It can be dangerous to use Imitrex if you suffer from or have a history of high blood pressure, angina (recurring chest pain), heart attack, high cholesterol, obesity, stroke, transient ischemic attack (mini-stroke), ischemic bowel disease, coronary artery disease, seizures, or blood vessel, kidney, or liver disease, heart disease, diabetes. Avoid alcohol. It can be dangerous to stop Imitrex taking suddenly.

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Dynamic changes of speech function were studied in patients with persistence aphatic disorders after stroke under the conditions of application of V2 vasopressin receptor agonist (1-desamino-8-D-arginin-vasopressin). In addition, CGP given together with MLT blocked its proapoptotic effect. All the pathways converged on 3-(3-hydroxyphenyl)-propanoic acid, which was transformed to hydroxyphenyl-ethanol and/or phenylacetic acid in few subjects. The subjects, who were actively watching their weight, participated in two consecutive tasks in a supermarket. Primary hepatic lymphoma: two case reports and a review of the literature. Effects can you drink alcohol while taking glyburide of repetitive subfailure strains on the mechanical behavior of the inferior glenohumeral ligament. Persistent dizziness and balance problems have been reported in some patients with unilateral vestibular pathology. Thus, the need for tools which in particular can make local structural alignments of RNAs is only increasing.

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We evaluated the accuracy of periodic density functional calculations for adsorption enthalpies of water, alkanes, and alcohols in silicalite and HZSM-5 zeolites using a gradient-corrected density functional with empirical dispersion corrections (PBE-D) as well as a nonlocal correlation functional (vdW-DF2). Using electrophysiological recordings, we found that ghrelin stimulated the activity of arcuate NPY neurons and mimicked the effect of NPY in the paraventricular nucleus of the hypothalamus (PVH). The present article highlights recent advances of the genetic cause of these conditions, and considers the role of somatic postzygotic genetic lesions in brain maldevelopment. These observations confirm previous results involving destructive lesions and establish the ventromedial nucleus as a hypothalamic locus involved in the control of growth hormone secretion. Comparison of cone beam computed tomography scans with and without simulation of head motion. Overall, 6/12 patients relapsed and received therapeutic DLI, starting at 1 x 10(5) CD3/kg with escalation every 2 weeks.

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