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Fosamax (Alendronate)

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Fosamax is used to treat and prevent osteoporosis (a condition in which the bones become thin and weak and break easily) in women who have undergone menopause and to treat osteoporosis in men.

Other names for this medication:
Alant, Alendix, Alendronate, Alenost, Bifosa, Denfos, Osteofos, Ostogee, Poronil, Ralenost, Restofos, Zophost

Similar Products:
Elavil, Prometrium, Microzide, Exelon, Diovan, Zyprexa, Lasix, Avana, Crestor, Desyrel

Also known as: Alendronate


{name} (alendronate) is a bisphosphonate (bis FOS fo nayt) medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures.

{name} is used in women to treat or prevent osteoporosis caused by menopause and in men and women to treat osteoporosis caused by taking steroids.

{name} is also used to increase bone mass in men who have osteoporosis, and to treat Paget's disease of bone in men and women.


Take Fosamax exactly as prescribed by your doctor. Fosamax is taken either once daily or once per week. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take Fosamax first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine. If you take this medicine only once per week, take it on the same day each week and always first thing in the morning.

Take with a full glass (6 to 8 ounces) of plain water. Do not use coffee, tea, soda, juice, or mineral water. Do not eat or drink anything other than plain water.

Do not crush, chew, or suck on an Fosamax tablet. Swallow the tablet whole.

For at least 30 minutes after taking Fosamax:

Do not lie down or recline. Do not take any other medicine including vitamins, calcium, or antacids.

Pay special attention to your dental hygiene while taking Fosamax. Brush and floss your teeth regularly. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using alendronate.

Fosamax is only part of a complete program of treatment that may also include diet changes, exercise, bone mineral density testing, and taking calcium and vitamin supplements. Follow your doctor's instructions very closely.

Store at room temperature away from moisture and heat.

Your doctor will determine how long to treat you with this medicine. Fosamax is often given for only 3 to 5 years.

Detailed Fosamax dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Drink a full glass of milk and call your local poison control center or emergency room right away. Do not make yourself vomit and do not lie down.

Overdose symptoms may include muscle cramps, numbness or tingling, tight muscles in your face, seizure (convulsions), irritability, and unusual thoughts or behavior.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Fosamax are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Fosamax if you are allergic to Generic Fosamax components. Be very careful with Generic Fosamax if you are pregnant or planning to have a baby, or you are nursing mother. Generic Fosamax can harm a baby. Be careful with Generic Fosamax if you suffer from or have a history of low blood calcium (hypocalcemia), a vitamin D deficiency, kidney disease, an ulcer in your stomach or esophagus. Be careful with Generic Fosamax if you are taking aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Naprosyn, Aleve); cancer chemotherapy; or oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone). Do not stop take it suddenly.

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Elective lymph node dissection in patients with melanoma: systematic review and meta-analysis of randomized controlled trials. Recommendations were given for entry and postgraduate level curricula. Introduction of substituted imidazole moieties delivered potent dual orexin receptor antagonists with nanomolar potency for hOX1R and hOX2R suitable for further fine-tuning. Mean daily intake of iodized salt and thyroid function tests were not significantly different. Our findings suggest that TLR/MyD88 signaling may be a therapeutic target for CAC intervention and MyD88 inhibitors may be a promising therapeutic modality for treating patients with colitis or CAC.

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Effective Treatment of Pleural Epitheloid Hemangio-endothelioma with Pazopanib: A Case Report. Diuretic drugs elicit their effects on sodium balance by specifically inhibiting sodium transport proteins in the apical plasma membrane of distal nephron segments. A number of real-world networks are heterogeneous information networks, which are composed of different types of nodes and links. The assessment of middle and superior cerebellar peduncle damage contributes to the explanation of cerebellar and/or brainstem symptoms and ambulatory impairment in MS. Simple protein separation by 1DE is a widely used method to reduce sample complexity and to prepare proteins for mass spectrometric identification via in-gel digestion. Evaluation of glycemic control in patients with type 2 diabetes mellitus in Chinese communities: a cross-sectional study. Studies on the binding of homologous and heterologous immunoglobulin G1. Strains isolated from patient A and the recipient pair were clustered within a closer range of evolutionary distances than were strains recovered from the recipient pair and patients B and C. Because before matrix mineralization, its expression is markedly diminished, we hypothesized that S100A4 negatively regulates the mineralization process.

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Characterization of Bacillus species used for oral bacteriotherapy and bacterioprophylaxis of gastrointestinal disorders. One of 4 optic nerve sheath meningiomas in patients with good visual acuity was subtotally resected with decompression of the optic canal. Newer trends in continuous monitoring of critically ill infants and children. The subcellular distribution of DeY1 protein was analyzed by electron microscope immunocytochemistry. Currently there is much exciting basic research in post-partum illnesses and, it is hoped, in the future women will not have to endure extensive emotional trauma during the post-partum period. Radiography revealed absence of a facet joint on the right side of L4-5.

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Effect of short-term positive airway pressure on blood pressure in controlled hypertensive patients with obstructive sleep apnoea syndrome: a prospective cohort study. To examine the possible inverse relation between osteoporosis and spondylosis by evaluating the association between bone mineral density and osteophyte formation or intervertebral disc narrowing using a semiquantitative scoring system. On the contrary, a serotonin-induced contraction in the rat stomach or ileum was highly sensitive, however, those of guinea pig were cozaar 50 mg cost less. Localizing and extracting filament distributions from microscopy images. An elevated ferritin level and obesity were negatively associated with ovarian volume and the AMH level, respectively, in women with PCOS. The NUSRT is cast as a linear algebraic expression that relates a nonuniformly sampled interferogram to an input spectrum. coli bacteremia have not changed, yet the mortality was lower in our series. We recently found that PAR-4 mRNA is up-regulated in experimental bladder inflammation regardless of the initiating stimulus. Themes arising from the identification and treatment of the disease include the difficulty of living in uncertainty and of maintaining and regaining normalcy in a superstitious society.

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Cardioprotective effect of miRNA-22 on hypoxia/reoxygenation induced cardiomyocyte injury in neonatal rats. Various molecular and biochemical techniques have been developed in the endeavour to study flaviviruses. Comparative studies of antihypoxic, neuroprotective and analgesic action of succinate-containing drugs. Periodontal and oral hygiene status of retarded children in Israel. However, pathogenesis remains largely unknown and no specific treatment is currently available for the patients. To identify and characterize a subgroup of schizophrenia patients with marked and dominating bodily sensations (cenesthesias and body image aberration). Mutations in the gene encoding parkin (PARK2) are the most common cause of autosomal recessive juvenile-onset and young-onset parkinsonism. The nontreponemal test result was shown to be a false-positive reaction by nonreactive Treponema pallidum immobilization and fluorescent treponemal antibody absorption tests. Risk for atherosclerosis is increased in women with polycystic ovary syndrome (PCOS).

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