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Femistra (Anastrozole)

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Femistra lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body. Femistra is used to treat breast cancer in postmenopausal women. Femistra is often given to women whose cancer has progressed even after taking tamoxifen (Nolvadex, Soltamox).

Other names for this medication:
Altraz, Altrol, Anabrez, Anastrocare, Anastrozole, Anatero, Anazol, Armilon, Armotraz, Femistra, Femitraz, Qubol, Redest, Rimidex, Stazonex, Xenosoul

Similar Products:
Keflex, Zyrtec, Vantin, Zocor, Lunesta, Depakote, Avodart, Decadron

Also known as: Anastrozole


Femistra is approved to treat certain types of breast cancer in women who’ve gone through menopause.

What breast cancer is

Breast cancer develops when cells in your breast start to grow and multiply (make more cells) more quickly than usual. With most breast cancers, the abnormal cells are encouraged to grow by the hormone estrogen.

If your breast cancer is stimulated by hormones, such as estrogen, certain tests will show that the cancer cells have receptors (attachment sites) for those hormones. This type of breast cancer is called hormone receptor-positive (HR+).

HR+ cancers can be treated with hormone therapies that lower the estrogen level in your body. And because most breast cancer is HR+, hormone therapies are also sometimes used to treat breast cancer whose receptor status isn’t known.

What Femistra does

Femistra is a hormone therapy that’s used to treat certain forms of breast cancer. It’s a type of drug called an aromatase inhibitor. Femistra works by stopping (inhibiting) the action of an enzyme called aromatase. (Enzymes are certain proteins that help chemical reactions to happen inside your body.)

The aromatase enzyme makes estrogen out of steroid hormones in your body, such as testosterone. Aromatase is found in various tissues, including your brain, fat, and skin.

Before menopause, estrogen is mainly produced by your ovaries. And just a small amount is made by the aromatase enzyme. But after menopause, your ovaries stop producing estrogen. At that point, the aromatase enzyme is the main way that your body makes estrogen. (And in men, estrogen is also mainly produced by the aromatase enzyme.)

By stopping aromatase from working, Femistra lowers the amount of estrogen in your body. This helps to stop estrogen from encouraging breast cancer to grow and spread.

How long does it take to work?

Femistra will start working soon after you begin taking it. But you won’t be able to notice this. Your doctor may order different kinds of tests during your treatment to check and see if the drug is working for you.


Usual Adult Dose for Breast Cancer:

Initial dose: 1 mg orally taken once a day Duration of therapy: Until tumor progression (treatment of advanced breast cancer); unknown (adjuvant treatment of early breast cancer) Uses: -Adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer; -First-line treatment of postmenopausal women with hormone receptor-positive or hormone receptor unknown locally advanced or metastatic breast cancer; -Second-line treatment of advanced breast cancer in postmenopausal women with disease progression following tamoxifen therapy.

Detailed Femistra dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Femistra are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Femistra if you are allergic to Generic Femistra components. This medicine has been shown to cause harm to the human fetus. It is unknown if this drug is excreted in breast milk. Use a non-hormonal method of birth control if you are a woman capable of becoming pregnant. Avoid alcohol. Avoid machine driving. Do not stop taking Generic Femistra suddenly.

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