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Fasigyn (Tinidazole)
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Fasigyn

Fasigyn is a drug used against protozoan infections. It is widely known throughout Europe and the developing world as a treatment for a variety of anaerobic amoebic and bacterial infections. It was developed in 1972 and is a prominent member of the nitroimidazole antibiotic class.

Other names for this medication:
Simplotan, Tindamax, Tinidazole

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Kamagra, Anafranil, Lopid, Prevacid, Ativan, Myambutol, Clarinex, Viagra, Kemadrin

Also known as: Tinidazole

Description

Fasigyn 500mg film-coated tablets contain 500mg of the active substance tinidazole. This medicine is an anti-infective agent. It is used to treat a variety of bacterial infections including: infections of the skin, blood, chest, lung, genitals or womb lining, an infection associated with stomach ulcers in combination with other drugs, infections caused by organisms called protozoa, such as amoebiasis and giardiasis (stomach infections) and trichomoniasis (a genital infection), vaginal infections (vaginitis) and gum infections (gingivitis).

It is also used before certain surgical operations to prevent bacterial infections developing.

You should ask your doctor if you are unsure why you have been given this medicine.

Dosage

Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

Take Fasigyn with a glass of water during or after a meal. Swallow the tablets whole. It is best to take the medicine at the same time each day.

For bacterial infections, this medicine is not recommended for use in children less than 12 years as it has not been tested in this age group.

For protozoal infections, Fasigyn 500mg film-coated tablets can be used in children and has not been shown to cause any different side effects or more problems than it does in adults.

The dose and length of treatment depends upon the infection being treated. If you are on dialysis, your doctor may prescribe a different dose.

The doses most commonly used for the different infections are shown in the table below:

For treating the infection associated with stomach ulcers. The usual dose is 1 tablet (500mg) taken twice a day. Your doctor will probably prescribe two other medicines to be taken with Fasigyn 500mg film-coated tablets. Treatment with the three medicines together will usually be for 1 week.

For treating most bacterial infections. The usual dose is 4 tablets (2g) on the first day then 2 tablets (1g) once a day or 1 tablet (500mg) twice a day. The usual length of treatment is 5 to 6 days.

For treating bacterial vaginitis (a vaginal infection) and acute ulcerative gingivitis (a gum infection). The usual dose is 4 tablets (2g) given as a single dose. For vaginitis you may be given 4 tablets (2g) on two consecutive days.

For preventing bacterial infections after surgery. Usually 4 tablets (2g) are given as a single dose about 12 hours before surgery.

For treating protozoal infections. For treating intestinal amoebiasis (a stomach infection). Adult: The usual dose is 4 tablets (2g) once a day for 2 to 3 days. Child: The usual dose is 50 to 60mg/kg of body weight once a day for 3 days.

For treating amoebic involvement of the liver (a liver infection). Adult: The usual dose is 3 to 4 tablets (1.5 to 2g) once a day for 3 to 6 days. Child: The usual dose is 50 to 60mg/kg of body weight once a day for 5 days.

For treating giardiasis (an abdominal infection) and trichomoniasis (an infection of the sex organs in males and females). Adult: The usual dose is 4 tablets (2g) given as a single dose. Child: The usual dose is 50 to-75mg/kg of body weight given as a single dose.

Your doctor will calculate the dose required for a child and may repeat the dose once if the infection has not cleared up completely.

Overdose

Immediately telephone your doctor or go to Accident and Emergency (Casualty) at your nearest hospital if you think you or anyone else may have taken too much Fasigyn. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Keep telephone numbers of these places handy.

If you take too many tablets, you may get an upset stomach, diarrhoea or skin rashes.

Storage

Keep all medicines out of the sight and reach of children.

Do not take this medicine after the expiry date stamped on the pack after EXP. The expiry date refers to the last day of that month.

Store below 25 C in a dry place. Store in the original package to protect from light and moisture.

Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

Side effects

The most common side effects associated with Fasigyn are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Fasigyn if you are allergic to Tinidazole, to any antibiotic from the class Amebicides. Do not take Fasigyn if you are allergic to any of the other ingredients comprised in Fasigyn. Do not take Fasigyn if you have a history of severe allergic reactions associated with using antibiotics. Do not take Fasigyn you have a blood disorder or a history of blood disorders. Do not take Fasigyn if you have any disease of the brain, spinal cord or nerves. Do not take Fasigyn you have central nervous system (CNS) disease, including epilepsy. Do not take Fasigyn you are in the first 13 weeks of pregnancy, planning to have a baby, or you are breastfeeding. Do not drive or operate machinery if you feel dizzy or numb after taking Fasigyn. Do not consume alcohol while you are taking Fasigyn and for 3 days afterwards. Alcohol may cause an upset stomach, vomiting, stomach cramps, headaches, sweating, and flushing (redness of the face).

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