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Estrace (Estradiol)

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Estrace is a female hormone (estrogen). It is used by women to help reduce vaginal symptoms of menopause (such as vaginal dryness/burning/itching). These symptoms are caused by the body making less estrogen. Estrace is available under different brand names.

Other names for this medication:
Bestradiol, Conjugase, Divigel, Edval, Espauz, Estogen, Estraderm, Estradiol, Estrofem, Evafem, Evalon, Evaride, Menocare, Mixogen, Oestrogel, Premarin, Progynon, Progynova, Sandrena

Similar Products:
Zantac, Remeron, Diflucan, Mircette, Lunesta, Indocin, Zithromax

Also known as: Estradiol


Estrace is used to treat symptoms of menopause (hot flashes, vaginal dryness, burning and irritation), prevent osteoporosis. Estrace is sometimes used as part of cancer treatment in women and men. Estrace medication is a form of estrogen - female hormone necessary for many processes in the body. Estrace works by replacing natural estrogens in a woman who can no longer produce enough estrogen. Estrace works for advanced prostate cancer by antagonizing male hormones. Estrace is also known as Estradiol.


Take Estrace exactly as it was prescribed for you. Follow all directions on your prescription label. Do not take this medicine in larger amounts or for longer than recommended.

Estradiol may increase your risk of developing a condition that may lead to uterine cancer. Call your doctor at once if you have any unusual vaginal bleeding while using this medicine.

Your doctor should check your progress on a regular basis (every 3 to 6 months) to determine whether you should continue this treatment. Self-examine your breasts for lumps on a monthly basis and have a mammogram every year while using Estrace.

If you need major surgery or will be on long-term bed rest, you may need to stop using this medicine for a short time. Any doctor or surgeon who treats you should know that you are using Estrace.

Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

Detailed Estrace dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Estrace are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Estrace if you are allergic to Estrace components. Do not take Estrace if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not take Estrace if you have a history of stroke or blood clot, circulation problems, hormone-related cancer (breast or uterine cancer), abnormal vaginal bleeding, bleeding or blood-clotting disorder. Be careful with Estrace if you have high blood pressure, angina, heart disease, high cholesterol or triglycerides, liver disease, kidney disease, asthma, epilepsy or other seizure disorder, migraines, diabetes, depression, gallbladder disease, hysterectomy, the risk of breast cancer, heart attack or stroke. Do not stop taking Estrace suddenly.

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