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Crestor (Rosuvastatin)

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Crestor is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver.

Other names for this medication:
Creston, Dorosur, Liparon, Provisacor, Richstatin, Rosumed, Rosuva, Rosuvas, Rosuvast, Rosuvastatin, Rosuvastatina, Rosuvastatinum, Rosuvastin, Rovartal, Rovast, Rozavel, Simestat, Sinlip, Turbovas, Visacor, Zyrova

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Also known as: Rosuvastatin


Crestor is indicated to treat high level of cholesterol. This remedy is acting by slowing the production of cholesterol in the body. Crestor is also known as Rosuvastatin calcium, Rosuvas, Rozavel. Crestor is HMG-CoA reductase inhibitor (statins).


Usual Adult Dose for Hyperlipoproteinemia:

Initial dose: 5 mg to 10 mg once a day with or without food Maintenance dose: 5 mg to 40 mg once a day with or without food

Usual Adult Dose for Hyperlipoproteinemia Type IIa (Elevated LDL):

Initial dose: 5 mg to 10 mg once a day with or without food Maintenance dose: 5 mg to 40 mg once a day with or without food

Usual Adult Dose for Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL):

Initial dose: 5 mg to 10 mg once a day with or without food Maintenance dose: 5 mg to 40 mg once a day with or without food

Usual Adult Dose for Hyperlipoproteinemia Type IV (Elevated VLDL):

Initial dose: 5 mg to 10 mg once a day with or without food Maintenance dose: 5 mg to 40 mg once a day with or without food

Usual Adult Dose for Atherosclerosis:

Initial dose: 5 mg to 10 mg once a day with or without food Maintenance dose: 5 mg to 40 mg once a day with or without food

Usual Adult Dose for Homozygous Familial Hypercholesterolemia:

Initial dose: 20 mg once a day with or without food Maintenance dose: 20 mg to 40 mg once a day with or without food

Usual Adult Dose for Prevention of Cardiovascular Disease:

Initial dose: 5 mg to 10 mg once a day with or without food Maintenance dose: 5 mg to 40 mg once a day with or without food Response to therapy should be estimated from preapheresis LDL-C levels.

Usual Geriatric Dose for Hyperlipidemia:

Initial dose: 5 mg once a day with or without food Maintenance dose: 5 mg to 20 mg once a day with or without food

Usual Pediatric Dose for Heterozygous Familial Hypercholesterolemia:

Pediatric patients 10 to 17 years of age: Usual dose range: 5 to 20 mg orally once a day with or without food. Doses should be individualized according to the recommended goal of therapy. Adjustments should be made at intervals of 4 weeks or more. Maximum dose: 20 mg orally once a day

Detailed Crestor dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Crestor are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Crestor if you are allergic to Crestor components. Do not take Crestor if you're pregnant or you plan to have a baby, or you are a nursing mother. Be careful with Crestor if you suffer from or have a history of liver, thyroid or kidney disease. Be careful with Crestor if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Be careful with Crestor if you have allergies to medicines, foods, or other substances. Do not eat fattening food that is high in cholesterol. Use Crestor with great care in case you want to undergo an operation (dental or any other). Avoid alcohol. Do not stop taking Crestor suddenly.

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The clonogenic and growth potential of established glioma cells correlated with DTX1 levels. The Peripheral NK Cell Repertoire after Kidney Transplantation is Modulated by Different Immunosuppressive Drugs. The structural characteristics of channels determining their susceptibility to blockade by organic mono- and dications were identified. The use of psychological approaches to augment clinical practice, such as education, reduction of anxiety and improving coping ability, are suggested. Despite mixed experimental data, some authors view bretylium as the drug of choice in hypothermic VF. Asthma is characterized by airway inflammation, smooth muscle hyperreactivity, and airway remodeling with excessive mucus production. Electrocardiograms in a Woman With Systemic Lupus Erythematosus. A novel in vivo platform for studying alveolar bone regeneration in rat. We examined central nervous system vascular malformations for the presence of DNA fragmentation which is the evidence of apoptosis. With the clinically imposed constraints of a fixed total dose and total treatment time, three parameters for each fraction (dose-rate, fraction duration, time of each fraction) were simultaneously optimized.

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Eighteen MBL-deficient and 63 MBL-sufficient adult patients with RRTI were all vaccinated with the 23-valent pneumococcal polysaccharide vaccine and antibodies to 14 pneumococcal serotypes were measured on a Luminex platform. Protection of T4 bacteriophage against inactivation during freezing and thawing by addition of peptides. Mitochondrial DNA variant in COX1 subunit significantly alters energy metabolism of geographically divergent wild isolates in Caenorhabditis elegans. Legislation concerning coccidiostats, limits for residues in food, monitoring and occurrence of residues in food is discussed. The FOS-based method does not need precise calibration table with high cost and complex measuring set-up, and Statistical results of the tests will provide us references in engineering application of the constant rate biased RLG INS. Overall mortality and survival, however, were similar to those for gastric transposition. One month after induction of the injury, beta-aminoproprionitrile (BAPN) or hyaluronic acid (HA) was injected into the tendon core of the right hind leg of each rabbit, the left hind leg being left untreated. Geographic and Ethnic Variations in Radiographic Disability Thresholds: Analysis of North American and Japanese Operative Adult Spinal Deformity Populations.

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We tested whether oral and pharyngeal squamous cell carcinoma cell lines differentially stimulated NK cell interferon-gamma (IFN-gamma) secretion and cytolysis using a clone of the NK-92-transformed human NK cell line, NK92.35. If external irritation or orbital discomfort cannot be managed with conservative local measures, then a trial of oral corticosteroids or orbital radiation can be considered. Recombinant human ATR, but not a kinase-inactive mutant, phosphorylated the same sites in Xchk1. The innate immune regulator STAT-5 is shown to regulate transcription of the ATR binding factor TopBP1, and this is critical for the induction of the ATR pathway. Transfection with the dominant negative mutant, Ras(Asn-17), inhibited IL-1 induced activation of the IL-8 promoter as well as of NF-kappa B and AP-1 synthetic promoters in transient transfection assays. Notes from the Field: Hepatitis C Outbreak in a Dialysis Clinic--Tennessee, 2014.

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Theory and practice in estimation of microorganism sensitivity to antimicrobial preparations by the disc diffusion method. In this approach, thermodiffusion is quantified through the variation in binary chemical potential and its temperature and concentration dependence. Divided attention in older but not younger adults is impaired by anxiety. These data support the view that management of RA should be adapted to country-specific needs. Diverticulum of the horizontal portion of the duodenum is a rare cause of upper gastrointestinal (GI) bleeding. The midline modified Taylor approach allows access to the thoracic epidural space via catheter advancement, while being below the terminus of the spinal cord and less likely to suffer contamination than the caudal approach.

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Effects of pollen load size and composition on pollen donor performance in wild radish, Raphanus sativus (Brassicaceae). On the contrary, there seems to be some evidence for a sympathetic hypoactivity in these patients and there seems to be good reason to abandon sympathectomy in the treatment. Treatment adherence was quantified utilizing ratio between RDD and PDD (Prescribed Daily Dose). Prenatal and post-natal imaging of an hepatic mesenchymal hamartoma. Widespread destruction of the skin induces a large necrotic mass and a break of the skin barrier. Insulin resistance and decreased insulin response to glucose in lean type 2 diabetics. The results of using TDB agree with the results of using capnography. We investigated whether altered proteoglycan metabolism occurs in vivo and may be reflected in the urine of PXE individuals by analyzing the excreted polysaccharides.

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Characterization of mechanisms governing the expression of the OMP genes should provide insight into host-parasite interactions. Serological and bacteriological detection of Brucella canis infection of stray dogs in Moreno, Argentina. Alcohol consumption patterns in Thailand and their relationship with non-communicable disease. Engineering interface-type resistive switching in BiFeO3 thin film switches by Ti implantation of bottom electrodes. Two patients suffering from chronic and slowly healing wounds post-surgery and preoperative radiotherapy are described. Hypertension is a common medical disease, occurring in about one third of young adults and almost two thirds of individuals over the age of 60. Moreover, wood combustion is another potential environmental risk factor and exerts a joint effect with NPC family history on NPC. However, the related structure-property relationships remain largely unclear and the reported results are inconsistent. Elementary school students 7 to 11 years of age recruited from 2 nearby schools located in a suburban area of southern Taiwan.

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Assessment of sarcopenia and changes in body composition after neoadjuvant chemotherapy and associations with clinical outcomes in oesophageal cancer. Hyperbaric oxygenation (HBO) offers an approach to overcome hypoxia. The impact of insulin-like growth factor-1 on the pattern of cardiac elongation factor-2 variants in a model of overload. Role of the mukB gene in chromosome and plasmid partition in Escherichia coli. Males and females offspring of F2-OF1 exhibited significantly elevated FBG and impaired OGTT. Serum creatine phosphokinase in muscular dystrophy during iodinated amino acid therapy. Apoptosis of human retina and retinal pigment cells induced by human cytomegalovirus infection. A randomized trial comparing injection therapy with hemoclip and with injection combined with hemoclip for bleeding ulcers. Truncal fat gains on ATV/r primarily led to increases in WC, which may reflect return to health, while on LPV/r increases in WC and triglycerides occurred.

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Immunohistochemical localization of inhibin/activin alpha, betaA and betaB subunits and follistatin in bovine oocytes during in vitro maturation and fertilization. Herein we compare imaging of splenic and lymph node tissue using iron/iron oxide core/shell nanoparticles (Fe NP) that have superior magnetic qualities to IONP, to determine whether improved negative contrast in T(2)-weighted MRI can enhance the diagnosis of small tumours in the reticuloendothelial system. Comprehensive chemical analysis of the rhizomes of Drynaria fortunei by orthogonal pre-separation and liquid chromatography mass spectrometry. Ultrasound-guided thrombin injection is the treatment of choice for femoral pseudoaneurysms. Based on the consolidated findings based on schools as units, results showed that participants had positive perceptions of the program, implementers, and benefits of the program. Wild-type and HA-H241Q viruses were similar in pathogenicity and grew to similar levels in mice, ducks, and cell cultures derived from both avian and mammalian tissues, suggesting that H5N1 HA proteins triggered at pH values in the range of 5.9 to 5.6 broadly support replication. Coverage of heel tissue loss by two pediculated flaps in a single procedure.

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A new method for characterization of N-sulfated glycosaminoglycans by a rapid and multisample nitrous acid treatment during an electrophoretic run and its application to the analysis of biological samples. Functional equivalence of WAIS-III/WMS-III digit and spatial span under forward and backward recall conditions. 31 cases with laryngeal lesion who had undergone the microlaryngoscopic operation with self-retaining by anesthesia were reviewed retrospectively from October 1, 1997 to compazine 5mg tab December 31, 2000. The Goldberg Anxiety and Depression Scale was used to measure caregiver affective illness. The serum insulin, fractional absorption, serum human C-peptide, and plasma glucose responses of normal fasting subjects were compared after the subcutaneous and intravenous administration of human insulin (recombinant DNA) and Novo Actrapid insulin.

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The risk of arachnoiditis from experimental nonionic contrast media. In endoscopic retrograde cholangiopancreatography (ERCP) the incidence of bacteremia, but not cholangitis, is reduced by prophylaxis and some do not recommend its routine use. Although Cr(VI) reduction has been studied in MR-1 and in other facultative bacteria under both oxic and anoxic conditions, a transition in specific reduction rates based on physiological conditions during growth is a novel finding. Our aim was to evaluate the immediate and midterm clinical results on 28 patients with acute lower limb ischemia treated with hybrid reconstructions on emergent basis, from January 2010 to March 2013 in our tertiary referral vascular center. The T cell receptor beta locus of the channel catfish, Ictalurus punctatus, reveals unique features. The effective ablation shape was similar to a chestnut and the ablation zone enlarged with the increasing of power and time. Since 1988 these tumors have been accepted as an occupational disease for woodworkers in Italy.

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Purification and characterization of PchB, a novel bifunctional enzyme displaying isochorismate pyruvate-lyase and chorismate mutase activities. Only 2 nurslings were found with rising antibody titres at 8-10 weeks of age, when infection could have been caused by environmental contamination. The renal scan commonly is used in patients with congenital anomalies such as ectopic and duplex kidneys, nonvisualized kidney on IVP and in children with oliguria or anuria secondary to diseases such as acute tubular necrosis, hemolytic uremic syndrome, and renal vein thrombosis. We verified that NS5A interacted with sorcin through domain I of NS5A, and phosphorylation of the threonine residue 155 of sorcin played a crucial role in protein interaction. Additional support for this hypothesis was provided by experiments with Rat1 fibroblasts in which conditional expression of Gadd153 conferred increased sensitivity to H(2)O(2). We review how beta-diversity is impacted by human activities, including farming, selective logging, urbanization, species invasions, overhunting rulide antibiotics , and climate change. Is human immunodeficiency virus RNA load composed of neutralized immune complexes?. The three mammalian loci encode, because of alternative initiation codon usage and splicing pattern, at least six Shc-like proteins.

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In tests, the algorithm was over 93 percent correct in detecting the first and second heart sounds. Immunophenotyping by flow cytometry, conventional karyotyping and fluorescence in situ hybridization for gene rearrangements were performed. This result gives the simplest and most straightforward answer to the Levinthal paradox. Twenty-seven patients were recruited: 7 of 21 patients stopped the sipatrigine infusion early due to adverse events as compared with none of 6 placebo patients. The combination of light scattering, small-angle neutron scattering, and neutron spin echo measurement techniques conclusively demonstrates that, upon addition of Na2SO4, these antibodies form strongly bound reversible dimers at dilute concentrations that interact with each other to form large, loosely bound, transient clusters when concentrated. Relation between regional function and coronary blood flow reserve in multivessel coronary artery stenosis. The AIPA density (mean 4.4/10,000 inhabitants/y) was four to five times higher in the most urbanized subdistrict (around 12) compared to the suburban subdistricts (2.5-3).

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