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Compazine (Prochlorperazine)

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Compazine is a phenothiazine derivative used in the treatment of schizophrenia and anxiety and to relieve severe nausea and vomiting. Compazine is an antipsychotic agent that works to promote postsynaptic inhibition of dopaminergic neurons.

Other names for this medication:
Bukatel, Compro, Emidoxyn, Eminorm, Ingametil, Meditil, Neurocin, Neurograin, Neurolice, Neuromol, Neuronit, Novapar, Nuroflow, Nuropar, Prochlorperazine, Procomp, Psygrain, Stemetil, Swigrain, Vasograin, Vertipro, Vestil

Similar Products:
Diflucan, Benemid, Colospa, Antivert, Norvasc, Clomid, Lopressor

Also known as: Prochlorperazine


Prochlorperazine suppository is used to control severe nausea and vomiting. This medicine should not be used to treat behavioral problems in older adult patients who have dementia.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain prochlorperazine. It may not be specific to Compazine. Please read with care.

Use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

Do not take rectal suppositories by mouth or use it in the vagina.

To use the suppository:

If the suppository is too soft to insert, chill it in the refrigerator for 20 to 30 minutes or run cold water over it before removing the wrapper. Remove the wrapper and moisten the suppository with cool water. Lie down on your side and use your finger to push the suppository well up into the rectum. Make sure to wash your hands with soap and water before and after using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For rectal dosage form (suppository): For severe nausea and vomiting: Adults—25 milligrams (mg) 2 times a day. Children—Use and dose must be determined by your doctor.


If you overdose Generic Compazine and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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This was found not to be due to any previous exposure to these odours or due to self-learning, but may be related to direct effects on the olfactory system, as reciprocal F(1) males show differential sensitivity to female odour cues. Furthermore, individual socioeconomic characteristics are associated with mortality independently of area characteristics. High dose steroid treatment and careful long-term follow-up is recommended. The diagnosis was made three years post-operatively and she then underwent reconstructive surgery. On the basis of the findings presented, some consequences for the application of citral, or its isomers, in food are discussed. Comparison of the effect of tetracyclines, sodium fluoride and strontium chloride on the content of citric acid in the rat incisor. with four doses of CII-APC-AdFasLp35Tet or a single dose of AdCMVsTACI (5 x 10(9) PFU), or both simultaneously, beginning 2 wk after priming with CII in CFA.

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This study provided evidence that the expression of local inflammatory cytokines can be attenuated in part by CO2 laser treatment, which may be closely related to the clinical effectiveness of this procedure. Recent reports suggest that polymorphisms in the carbonic anhydrase gene CA6 (also known as gustin) may explain additional variation in the bitterness of 6-n-propylthiouracil beyond that explained by variation in the bitter receptor gene TAS2R38. The animals were divided in 5 groups using different techniques of vesical augmentation. Its expression in genital ridge initiates from day 3 and is restricted to mesenchymal cells, which differentiate into the Sertoli cells. Reliability proves to be good for all types of assistive devices. A cross-sectional descriptive study was conducted in two tertiary cancer hospitals of Nepal. Policymakers should urgently institute systems for accountability and ethical practice and regularly monitor all medical interventions, before large scale exploitation of the rural markets begins. However, costs and accessibility by the poorest are important concerns, and other options such as supplementation and efforts to improve complementary feeding also require attention. Intersensory attention (IA) describes our ability to attend to stimuli of one sensory modality, while disregarding other modalities. Network analysis identifies genes/proteins most differentiated during the healing process, and their organization in functional pathways or modules, and their distribution into gene ontology categories of biological processes, molecular functions, and cellular localization.

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The other process was accumulation of matrix around stent struts, which was suggested to be linked to infiltration of inflammatory cells in the same zone. Possible relationships between NMS and lethal catatonia are explored. The single-active-X: functional differentiation at the chromosome level. The present study synthesizes, advances and extends previously described work about these muscles and extends the hypotheses and concludes that: (a) the flexor digitorum superficialis to the fifth finger is currently under adaptive evolution, (b) the anconeus has currently stabilized its evolution and is serving as a transient stability augmenter during a short portion of the human lifespan, and (c) the entire distal upper extremity is currently in the process of undergoing evolutionary change. Attention is focused on the vascular basis of skin flaps, their clinical application, and their advantages over other methods of soft tissue replacement. The recently proposed Research Domain Criteria (RDoC) project has the potential to stimulate new research and overcome many of the limitations of the Diagnostic and Statistical Manual of Mental Disorders taxonomy. Moving beyond single and dual diagnosis in general practice: many patients have multiple morbidities, and their needs have to be addressed. The challenging structure and the interesting biological activity of (-)-callystatin A fueled our interest in the synthesis of this marine natural product. Low mitochondrial DNA content associates with familial longevity: the Leiden Longevity Study.

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We determine the size of the excitons for different organic molecules and polymers by time dependent density functional theory calculations. Thus, none of the recently published studies has provided reliable proof of the possibility of digital intraoral palpation, although palpation of the muscle is part of most of the examination catalogs for clinical functional analysis and functional therapy. In cancer cells, reactive oxygen species (ROS) play important roles in the migration and invasion of cells. From Hippocrates to the Eskimo--a history of techniques used to reduce anterior dislocation of the shoulder. Structural equation modeling was used to test the effects of neurochemistry and MMN amplitude on DST performance. The purpose of the present study was to investigate the role of central arginine vasopressin (AVP) in corticotropin releasing hormone (CRH) induced fever in the rat. Prospective study of children with normal general and neurologic examinations who had seizures with ictal vomiting and EEG with occipital spikes. Papillon-lefevre syndrome (PLS) belongs to a heterogeneous group of skin diseases that are characterized by hyperkeratosis of palms and soles. To discuss peripheral nerve regeneration under immunosuppression.

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Antibacterial multilayer films fabricated by layer-by-layer immobilizing lysozyme and gold nanoparticles on nanofibers. The authors searched the English literature regarding CAIS and PJAC. In a separate survey, dermatologists were asked about treatment patterns and satisfaction with currently available therapies. Statistical analysis was performed by using independent sample t-test and Spearman correlation analyses. Benign and malignant tumor cells can express altered adhesion properties, and these features can be associated with their proliferative and invasive characteristics.

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In 45 SMIDs who has been fed with carnitine-deficient formulas and/or receiving valproate, the serum free-carnitine levels were examined. Association between hemoglobin Groene Hart and hemoglobin J-Paris-I: first case in Spain. Those with N0/1 or maxillary sinus SCNEC-HN had a better prognosis than those with N2 disease or cancers at other sites, respectively. These pathology images typically have very high resolution, making it difficult to search based on image content. Increased Aortic Valve Calcification in Familial Hypercholesterolemia: Prevalence, Extent, and Associated Risk Factors. On the basis of the methods developed it was possible to compare respiration intensity, respiration quotients, and sensitivity against some metabolic inhibitors in both morphological forms. Declines in stillbirth and neonatal mortality rates in Europe between 2004 and 2010: results from the Euro-Peristat project.

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Structural features of mossy cells in the hamster dentate gyrus, with special reference to somatic thorny excrescences. It is probably the immunosuppressive state per se that may cause the resistance of his muco-cutaneous lesion to anti-viral agent. Colon cancer, colonic adenoma and normal colonic mucosal specimens were obtained under institutional review board approval and analyzed for the expression of Fz1 and Fz2 by confocal fluorescent immunohistochemistry and Wnt-specific membrane array. The aim of this investigation originated in the observation of different behaviors in the population of a health district in Granada, Spain, and in the apparent concentration of certain diseases in the pediatric population of the gypsy minority. Incapacity of the evolution of Trypanosoma cruzi in the hemocele of triatomids.

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Yet, the lack of a robust phylogenetic framework for Catasetinae has hampered deeper insights in origin and evolution of sexual systems. Depression and sensitization to stressors among young women as a function of childhood adversity. The mechanism of this uncoupling involves the cyclin B-Cdc2-dependent proteolytic cleavage of the N-terminal ERK-binding domain of MEK1 and the phosphorylation of Thr(286). Eyes with larger areas of retinal nonperfusion and greater severity of DR were found to have the most recalcitrant DME, as evidenced by a greater number of macular photocoagulation treatments and less reduction in SD OCT CMT compared with eyes without retinal nonperfusion. In this review, we discuss evidence in support of the theory that HMGB1 is an important mediator in SLE and may be considered a new autoantigen. In addition, preterm babies who developed NEC after 2 weeks of age appear to be smaller and sicker. The sequence of the fusion promoters is similar to the sigma(70)-specific promoter consensus. Visceral leishmaniasis in the crab-eating fox (Cerdocyon thous) in south-east Brazil.

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In the last decade, the biopsychosocial concept of medicine had flourished clinically in the form of consultation-liaison (C-L) psychiatry. The steady state stability was confirmed during a five hour period of liquid ventilation in five preterm lambs. Puerarin and TIP were orally administrated to ovariectomized rats, infancy or adult mice and estrogen-treated mice at the doses of 150, 300 and 600 mg/kg for 5-9 days. Challenges engendered by this lack of information is further amplified by inter- and intraspecies differences in the specificity and affinity of substrates and inhibitors, prohibiting a simple extrapolation of probe substances used in human CYP research. A detailed description and direct comparison of the different DIV types was missing. His studies, based on a unique quantitative approach to the grading and recording of clinical data, introduced cardiac physiology to the bedside, brought accuracy to the preoperative assessment of cardiac disease, and became the foundation for much of our current understanding about congenital and rheumatic heart disease and pulmonary hypertension. Left ventricular hypertrabeculation/noncompaction coincidentally found in sporadic inclusion body myositis. Despite recent progress in medical and surgical treatment, acute type B aortic dissection still carries a high mortality rate. Changes in IGF-1 indicate similar long-term effects in obese patients.

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Further, the pathological causes of altered development or of a sudden loss of gait stability, as well as the environmental influence are investigated. Oral granisetron 1 mg and ondansetron 16 mg plus dexamethasone are safe and effective in preventing nausea and vomiting related to emetogenic chemotherapy. The luvox dosage strengths aim of the present study was to investigate whether sFSTG are associated with specific changes in the electrical brain activity that might indicate an involvement of regulatory emotional processes and working memory. A 30-fold increase in excretion of L-DOPA, distinct elevation in synthesis of dopamine and noradrenaline as well as inhibition of adrenaline synthesis occurred in schizophrenic patients at an acute period after administration of 0.1 g of L-DOPA per os (L-DOPA test). Availability of results from clinical research: failing policy efforts.

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Electrical and pharmacological cardioversion (ECV, PCV) are important treatment options for symptomatic patients with recent onset atrial fibrillation (AF). 24 patients completed the trial (11 treated with cimetidine, 13 with placebo). Further evidence for reabsorption of hemoglobin iron lost into the intestine in hookworm infected subjects. Patients with uveitis were compared with those who did not have eye involvement. Pediatric access to care was excellent for children with the exception of Germany and the United States where there is an inadequate referral system. In fact, promising clinical data exist albenza dosing pinworm that treatment with epigenetic agents can diminish chemotherapy resistance in a number of tumor types including chronic myelogenous leukemia, colorectal, ovarian, lung and breast cancer.

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COMT Val158Met modulates subjective responses to intravenous nicotine and cognitive performance in abstinent smokers. Thus, it has been difficult to evaluate the relative contribution of each cardiovascular risk factor to systemic oxidative stress and to determine whether such risk factors act independently and are applicable to the general population. Here we show that an amino acid substitution (T29I) increases the native-state stability of goat alpha-lactalbumin against the guanidine hydrochloride-induced unfolding by 3.5 sumycin 500 mg uses in hindi kcal/mol. Nutrition education materials from the National Institutes of Health: development, review, and availability. Skin deep: A bioactive formulation for dermal delivery of antihistamines is obtained by using the original properties of catanionic associations towards self-assembly in water. Cardiac troponin I and T are potent tools for risk stratification and clinical decision-making for patients in the appropriate clinical setting of an acute coronary syndrome. The effects of clomiphene on endocrine function in male patients with adrenocortical infufficiency and following castration. A random-effects model and the generic inverse variance method were used for quantitative data synthesis.

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Strongyloidiasis should be included in the differential diagnosis of mass upper GI bleeding in immunosuppressive patients living in, or originating from, endemic areas. We presented here the different technics used in 2001 in the management of hemangioma and superficial vascular anomalies insisting on a multidisciplinary approach. Intravenous trifluoperazine (Stelazine) as a postoperative anti-emetic. A 25 year old patient presented with several types of paroxysmal tachycardia. The evolutionary and ecological factors underlying this variation are unclear. In this review, we summarize the recent advances in this field as well as discussing the significance of CETP in reverse cholesterol transport, a major protective system against atherosclerosis. The impact of electron probe microanalysis on the study of geological and planetary materials has been dipyridamole brand name australia tremendous. A randomized trial of intracoronary thrombolysis in a multicenter, geographically limited community has been undertaken.

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Estrogen stimulates the proliferation of pituitary cells, in particular mammotrophs. In this what does the medication tramadol do article, we review the literature about postcolonoscopy CRC risk and the most common explanations. Delusional depression is associated with a high rate of relapse, and some form of continuation therapy is clearly required. Echographic examination disclosed retinal detachment in temporal side from optic disk to equator, a medium reflectivity rounded, homogeneous lesion with rapid growing and positive signs of vascularity. Finally, strengthening national policies for health at work, promotion of healthy work and work environment, sharing healthy work practices, developing updated training curricula to improve human resource knowledge including occupational health professionals are recommended. Whereas the efficacies of the NR2B subunit selective NMDA antagonists were similar in EcR/rNR1a2B cells and in neurones, their maximal inhibitory effects were significantly higher in cells expressing NR1a/NR2B recombinant receptors. An increase in the level of ergosterol biosynthesis was also observed in the tri5 disrupted transformant in comparison with the wild type strain. Discussion paper: experimental basis of the unit membrane theory.

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Context-dependent memory was tested and self-reports of affect were taken. Final lengthening was also observed: both distinctively long and short vowels were longer in word-final position than in word-initial position. Modification of cardiac dynamics in intraventricular conduction disorders. No minimum serum PSA value was needed to potentially detect radiographic disease after surgery. Besides we stated, that increased levels of epoxycholesterols cold be one of the factors responsible can dogs have generic zyrtec for PIH. Unveiling the hidden structure of complex stochastic biochemical networks.

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The aim is to inform and develop coherent and effective policies that address the key rate-limiting steps critical to improving nutrition-related public health. Each patient was stabilized with metoprolol with or without diuretic therapy prior to admission to the trial. The precise molecular mechanism involved in RPE-neural crest cell interaction is still unknown, and the quail silver mutation is considered to be a good experimental model for studying the role of neural crest cells in vertebrate eye development. A light and electron microscopic study of the inferior olivary nucleus of the squirrel monkey, Saimiri sciureus. Furthermore, ERCP plays an important role in the preoperative differentiation between cystic neoplasms and pancreatic pseudocysts. Intratumoral injections of pGEG.FasL into PC induced significant growth suppression of the xenograft tumors, in which typical characteristics of apoptosis were demonstrated by TUNEL staining and electron microscopic observations. Height, weight and body mass index (BMI) in psychiatrically ill US Armed Forces personnel. Correspondingly, during mouse embryonic development strong Trps1 expression is found in the cartilage condensations, the developing joints, the hair follicles and in the developing snout. Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization.

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This preparation contained an L-alanine reductase which reduces L-alanine to L-alaninol, a constituant of the mycoside C(2). Assessment of disc degeneration and BMD pre-operatively improves the understanding of the biomechanical effects of a lumbar laminectomy. Chronic hypertension is a serious medical complication in pregnancy with increased maternal and perinatal morbidity and mortality. As expected the dental professionals are generally well informed, but not as well informed as could be expected. An uncommon sequel of facial trauma (importance of the autopsy for medicolegal purposes). Based on extensive virological analyses, we determined that Ifi27l2a protects mice from WNV-induced mortality by contributing to the control of infection of the hindbrain and spinal cord, possibly by regulating cell death of neurons. Ciliated secretory cells in the pars distalis of the mouse hypophysis. Duct drainage by a duct to mucosal anastomotic technique, whether to stomach, small bowel or urinary bladder, prevents pancreatitis and preserves normal exocrine and endocrine function. The choice of conduits for surgical revascularization in patients with aortic coarctation can be puzzling, as the internal thoracic arteries can be dilated, atherosclerotic and unsuitable for grafting. This laboratory assay may help prevent the occurrence of the fatal events caused by DVT with use of early therapeutic intervention, such as heparinization.

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