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Celkast (Montelukast)
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Celkast

Celkast is a leukotriene (loo-koe-TRY-een) inhibitor that is used to prevent asthma attacks in adults and children at least 2 years old. Celkast is also used to prevent exercise-induced bronchoconstriction (narrowing of the air passages in the lungs) in adults and children who are at least 6 years old.

Other names for this medication:
Admont, Adomont, Afineday, Aldbest, Almont, Alvergy, Alzero, Astham, Breathezy, Briocold, Centiluk, Cetrite, Coekastle, Deriphyllin, Ferodr, Fexoquin, Histakind, Leezet, Lelet, Levasma, Lupimon, Luvle, Monamra, Moncy, Montair, Montal, Montas, Montasame, Montasma, Monteleo, Montemac, Montilife, Montlu, Nucez, Odimont, Ontelio, Pulmokast, Reakst, Renea, Reokast, Riokast, Rivoce, Sanmonte, Sigcet, Symkast, Tastymont, Telekast, Tykast

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Also known as: Montelukast

Description

Celkast tablets, produced by Merck Sharp & Dohme, are indicated in the treatment of asthma as add-on therapy in those patients with mild to moderate persistent asthma who are inadequately controlled on inhaled corticosteroids. It helps prevent the wheezing, chest tightness, and shortness of breath caused by asthma and decreases the number of asthma attacks. The medicine is used to prevent exercise-induced bronchoconstriction (narrowing of the air passages in the lungs). It also helps treat seasonal and perennial allergic rhinitis. The active substance contained in the medication is Montelukast, a leukotriene receptor antagonist, that stops leukotrienes, chemical messengers in the immune system, from causing inflammation in the lungs and nose, preventing asthma symptoms and allergies.

Dosage

Asthma: - Adults (15 years of age and older): 10 mg a day. - Children (6 to 14 years of age): 5 mg a day. - Children (2 to 5 years of age): 4 mg a day. Celkast should be taken once a day in the evening. Exercise-Induced Bronchoconstriction (EIB): - Adults (15 years of age and older): 10 mg a day. - Children (6 to 14 years of age): 5 mg a day. - Children (2 to 5 years of age): 4 mg a day. For prevention of EIB, Celkast should be taken at least 2 hours before exercise. Do not take more than one dose in 24 hours. Allergic Rhinitis: - Adults (15 years of age and older): 10 mg a day. - Children (6 to 14 years of age): 5 mg a day. - Children (2 to 5 years of age): 4 mg a day. For allergic rhinitis, Celkast should be taken once a day. Patients with both asthma and allergic rhinitis should take only one Celkast dose daily in the evening. Pediatric patients are advised to take chewable tablets.

Overdose

If you overdose Celkast and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Celkast overdosage: stomach pain, agitation, insomnia, thirst, migraine, vomiting.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep this medicine in the original bottle. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Celkast are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take the Celkast if you are allergic to Montelukast or any of the other ingredients of this medicine. Do not use the tablets to treat an acute asthma attack, including Status Asthmaticus. Do not use the drug if you suffer from severe kidney failure. Do not combine the medication with drugs which induce the CYP450 enzyme system (phenobarbital and rifampin), as they may decrease the effects of Montelukast. Do not use the medication if you have a phenylketonuria, as Celkast contains phenylalanine. Do not take the medication tablets during pregnancy or while breastfeeding without consulting your doctor. Avoid drinking alcohol while taking Celkast tablets, as it may cause excessive drowsiness. Do not give this medicine to children less than 2 years of age.

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Incidence of CDAD varies ordinarily between 1 to 10 in every 1,000 admissions. Ag-NOR staining in human chromosomes: differential staining in normal and leukemic bone-marrow samples. The HIV-1 like particles released from inhibitor-treated cells contained almost exclusively p55 and other gag precursors, but not p24. Visual loss after blepharoplasty: incidence, management, and preventive measures. This clinical commentary critically reviews each of the proposed theories and highlights that muscle alterations are observed prior to onset of Achilles Tendinopathy and during the disease. Since IL-6 responsive cell-types may participate in the pathogenesis of glomerular inflammation, we studied the secretion of IL-6 by rat MCs, using the IL-6 dependent hybridoma cell line B9.

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In the vernalization pathway, VIL1, along with VERNALIZATION INSENSITIVE 3 (VIN3), is necessary for the modifications to FLC and FLM chromatin that are associated with an epigenetically silenced state and with acquisition of competence to flower. Erratum: Dual-Hormone Changes Are Related to Bargaining Performance. It is important to understand the mechanism of the regulation of ocular circulation under physiological conditions because the impairment of ocular circulation should cause severe retinal disorders. The main cause for increased vertical excursion of the CoM in the children with CP was the increased knee flexion of both legs during double support. The present research used a within-persons approach to simultaneously test the moderating effects of intentions based on instrumental attitude, affective attitude, anticipated affective reactions, injunctive norms, descriptive norms, and moral norms on the intention-behavior relationship and the impact of controlling for intention stability, self-efficacy, and past behavior. Sixty-four patients with gallstones and gallbladder polyps were enrolled after providing informed consent. Five differentially expressed miRNAs between the two tissues types were also identified by degseq software. These clear discriminations can be described by the ability of a bacterium to change its metabolism in terms of the content and structure of cellular macromolecules under heavy metal stress. Effects of dietary sodium deprivation on erythrocyte sodium concentration and cation transport in normotensive and untreated hypertensive subjects.

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As a result, continuous T cell development requires that BM-derived progenitors be imported into the thymus throughout adult life. Hospital-treated psychosis and suicide in a rural community (1877-2005). Enzyme combined with detergent and nucleases can remove cells from porcine aortic valves. Our results show for the first time that loading anti-hTfR IgG3-Av with a biotinylated toxin enhances the cytotoxicity of the fusion protein alone. The concentrations of the two chalones in the skins of treated animals varied in inverse proportion to the alterations in the DNA synthesis and the mitotic rate, with one exception. In all cases, it bound progesterone at 4 degrees C with an equilibrium affinity constant of the order of 10(6) l/mol, but did not bind cortisol. Mutagenicity analysis of water samples from Camalti Saltern, Turkey were investigated by applying Salmonella mutagenicity test.

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The potential of the LIBS-analysis for finding the proper plant species for phytoremediation is compared with the results of microradiography measurements at the HERCULES source at ENEA, Rome (Italy) and X-ray microradiography experiments at the ELETTRA Synchrotron, Trieste (Italy). We determined the long-term outcome in patients with superficial bladder cancer (Ta and T1) undergoing routine second transurethral bladder tumor resection (ReTURB) in regard to recurrence and progression. Service accountability and community participation in the context of health sector reforms in Asia: implications for sexual and reproductive health services. Benzamide derivatives as dual-action hypoglycemic agents that inhibit glycogen phosphorylase and activate glucokinase. However, limited studies have investigated the mechanism through which peroxynitrite exerts anti-adrenergic effects. Mean aortic clamping time was 39 minutes and mean operative time 194 minutes. Growth factor-induced cell migration and proliferation are essential for epithelial wound repair.

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We propose a novel method, referred to as BASE (binding association with sorted expression), to infer TF activity changes from microarray expression profiles with the help of binding affinity data. Physiotherapy interventions are provided to patients within Australian emergency departments in selected settings. Rate of cognitive change measured by neuropsychologic test performance in 3 distinct dementia syndromes. After a careful search of the literature, I am unable to find any scientific evidence for the validity of the theories, testing methods, or treatments given to these patients by clinical ecologists. The French Aviation Authorities have developed a system called SIEVERT, using calculation codes to monitor effective radiation doses. Plasticity of neuronal excitability: Hebbian rules beyond the synapse. The graphene-nanoflake on the graphene-nanoribbon is applicable to ultra-fast response oscillators, data storage media, switches, sensors, and quantum computing. Furthermore, under such conditions, nPKCdelta, whose subcellular localization is cell cycle dependent, showed a cytoplasmic and perinuclear localization by immunohistochemistry, this being typical for cells in G0/G1 phase.

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Toward the development of evidence-based guidelines for the management of methicillin-resistant Staphylococcus aureus otitis. Candidatus Ehrlichia walkerii: a new Ehrlichia detected in Ixodes ricinus tick collected from asymptomatic humans in Northern Italy. Although the pathologic mechanisms responsible for glomerular proteinuria have not been completely clarified, yet, it has become evident that structural and functional tenormin 50 mg astrazeneca abnormalities of podocytes play an early and important role. Dlx3 is expressed in osteoblasts, and overexpression of Dlx3 in osteoprogenitor cells promotes, while specific knock-down of Dlx3 by RNA interference inhibits, induction of osteogenic markers. The results suggest that estrogen receptor-beta may be the predominant subtype expressed in human periodontal ligament cells and may actively participate in the osteogenic differentiation process of human periodontal ligament cells, both in male and in female subjects. After 5 weeks, the animals were sacrificed and hair was obtained for analyses. Studies have shown that patient care and treatment has improved with the use of simulators, allowing true mental and physical confidence of the practioners before and during patient care. The discrepancy between historical and zooarchaeological data is probably the result of inadequate sampling and of an extirpation gradient related to impoundments that have been constructed in this drainage during the last century.

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