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Cefpodoxim

Cefpodoxim (generic name: cefpodoxime proxetil; brand names include: Cefocep) is used for treating mild to moderate infections caused by certain bacteria. Cefpodoxim is an oral third generation cephalosporin antibiotic. It is used to treat infections such as pneumonia; bronchitis; gonorrhea; and ear, skin, throat, and urinary tract infections. Cefpodoxim works by interfering with the formation of the bacteria's cell wall so that the wall ruptures, resulting in the death of the bacteria. It treats many kinds of infections, including those of the respiratory tract, skin, and ears.

Other names for this medication:
Belpro, Cefdolife, Cefdox, Cefirax, Cefobid, Cefodox, Cefolex, Cefomin, Cefoprox, Cefpodoxime, Cefpodoximum, Cefpolek, Cepdoxim, Cepodem, Desbac, Dofixim, Kindcef, Orelox, Otreon, Pedicef, Podomexef, Rovantin, Sefox, Starpod, Tambac, Taxetil, Trucef, Weijiexin, Ximeprox, Ximocef

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Also known as: Cefpodoxime

Description

Cefpodoxim is an oral, third-generation cephalosporin antibiotic. It is active against most Gram-positive and Gram-negative organisms. Notable exceptions include Pseudomonas aeruginosa, Enterococcus, and Bacteroides fragilis. Currently, it is only marketed as generic preparations in the USA, according to the FDA Orange Book. It is commonly used to treat acute otitis media, pharyngitis, sinusitis, and gonorrhea. It also finds use as oral continuation therapy when intravenous cephalosporins (such as ceftriaxone) are no longer necessary for continued treatment.

Cefpodoxim inhibits cell wall synthesis by inhibiting the final transpeptidation step of peptidoglycan synthesis in cell walls. It has well established pharmacokinetic profile with absorption of 50%. It is indicated in community acquired pneumonia, uncomplicated skin and skin structure infections, and uncomplicated urinary tract infections.

Dosage

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

You or your child must take the tablets with food, while the oral liquid may be taken with or without food.

Shake the oral liquid well before each use. Measure the medicine with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.

Keep using this medicine for the full treatment time, even if you or your child feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (suspension or tablets): For bronchitis: Adults and teenagers 12 years of age and older—200 milligrams (mg) every 12 hours. Children younger than 12 years of age—Use and dose must be determined by your doctor. For ear infections: Infants and children 2 months to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 milligrams (mg) per kilogram (kg) of body weight every 12 hours. Infants younger than 2 months of age—Use and dose must be determined by your doctor. For gonorrhea: Adults and teenagers 12 years of age and older—200 milligrams (mg) taken as a single dose. Children younger than 12 years of age—Use and dose must be determined by your doctor. For pneumonia: Adults and teenagers 12 years of age and older—200 milligrams (mg) every 12 hours. Children younger than 12 years of age—Use and dose must be determined by your doctor. For sinusitis: Adults and teenagers 12 years of age and older—200 milligrams (mg) every 12 hours. Infants and children 2 months to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 milligrams (mg) per kilogram (kg) of body weight every 12 hours. Infants younger than 2 months of age—Use and dose must be determined by your doctor. For skin infections: Adults and teenagers 12 years of age and older—400 milligrams (mg) every 12 hours. Children younger than 12 years of age—Use and dose must be determined by your doctor. For sore throat and tonsillitis: Adults and teenagers 12 years of age and older—100 milligrams (mg) every 12 hours. Infants and children 2 months to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 milligrams (mg) per kilogram (kg) of body weight every 12 hours. Infants younger than 2 months of age—Use and dose must be determined by your doctor. For urinary tract infections: Adults and teenagers 12 years of age and older—100 milligrams (mg) every 12 hours. Children younger than 12 years of age—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include nausea, vomiting, stomach pain, and diarrhea.

Storage

Store Cefpodoxim at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 to 86 degrees F (15 to 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Cefpodoxim out of the reach of children and away from pets.

Side effects

The most common side effects associated with Cefpodoxim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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