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Caverject (Alprostadil)
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Caverject

Caverject injection and suppositories are used to treat certain types of erectile dysfunction (impotence; inability to get or keep an erection) in men. Caverject injection is also sometimes used in combination with other tests to diagnose erectile dysfunction.

Other names for this medication:
Alpostin, Caverject, Edex, Muse, Prostin, Vitaros

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Also known as: Alprostadil

Description

Caverject injection is used to treat certain heart, lung, and blood vessel problems in infants. It is used to temporarily keep the ductus arteriosus (blood vessel in the heart) open before having a surgery.

This medicine is to be given only by or under the supervision of your child's doctor.

This product is available in the following dosage forms:

  • Solution

Dosage

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For the treatment of erectile dysfunction:
    • For injection dosage form:
      • Adults—1.25 to 60 micrograms (mcg) as a single dose once a day. Your exact dose will be determined by your doctor. Inject this medicine very slowly into your penis as shown to you by your doctor 10 to 30 minutes before intercourse. Allow 5 to 10 seconds to completely inject the dose. Do not inject more than one dose within 24 hours. Also, do not use this medicine for more than 2 days in a row or more than 3 times a week.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose can cause fainting, or a painful and prolonged erection.

Storage

Store at the room temperature 25°C (77°F)or below. The medication should be used within 24 hours after opening. Do not freeze it. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Caverject are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Caverject if you are allergic to it, or if you have:

sickle cell anemia or the sickle cell trait; leukemia; a tumor of the bone marrow (multiple myeloma); a curved or deformed penis; penile fibrosis or Peyronie's disease; if you have a penile implant; or if you must avoid sexual intercourse for health reasons.

Tell your doctor if you have ever had:

heart disease; high or low blood pressure; or bleeding problems.

Caverject, Caverject Impulse, Edex, or Muse should not be used by women or by anyone under 18 years old.

While using Caverject pellets, use condoms during sex if your partner is pregnant or able to get pregnant. The effects of Caverject on an unborn baby at conception or during pregnancy are unknown.

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Localization of a microheterogeneity in the amino acid sequence of bovine growth hormone. Expression analysis of microRNAs related to the skin ulceration syndrome of sea cucumber Apostichopus japonicus. Disease-specific human glycine receptor alpha1 subunit causes hyperekplexia phenotype and impaired glycine- and GABA(A)-receptor transmission in transgenic mice. Translation of MOPC 21 plasmacytoma cell mRNA in a cell-free wheat germ system. Human and porcine arterial heterografts in the dog (use of enzymes and protection of the graft with pericardium and plastic material).

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