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Carim (Modafinil)
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Carim

Carim is a medication to treat sleepiness due to narcolepsy, shift work sleep disorder or obstructive sleep apnea. While it has seen off-label use as a purported cognitive enhancer to improve wakefulness in animal and human studies.

Other names for this medication:
Alertec, Carim, Dekast, Modafinil, Modafinilo, Modalert, Modapro, Modatec, Modavigil, Modfil, Modiodal, Provake, Renea, Vigia

Similar Products:
Silagra, Wellbutrin, Plaquenil, Famvir, Ultram, Floxin, Rogaine, Glucotrol

Also known as: Modafinil

Description

How Carim works to help increase wakefulness and decrease sleepiness isn’t clear. The drug works in the brain to increase amounts of certain chemical messengers such as dopamine. It also seems to affect the messenger glutamate in certain areas of the brain.

These actions may result in stimulation of brain activities, which could make you feel less tired.

How long does it take to work?

Carim begins to work within 30 to 60 minutes of when you take it. If you take it with food, the drug might take slightly longer to start working.

Dosage

Dosage for adults is 100 mg per day. Take with or without food.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children.

Side effects

The most common side effects associated with Carim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Carim if you have ever had an allergic reaction or skin rash while taking modafinil or armodafinil (Nuvigil).

To make sure Carim is safe for you, tell your doctor if you have:

angina (chest pain); cirrhosis or other liver problem; kidney disease; high blood pressure, heart disease, or history of heart attack; a history of mental illness or psychosis; or history of alcoholism or drug addiction.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Carim can make certain birth control less effective. Hormonal contraception (birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective enough to prevent pregnancy during your treatment. Talk with your doctor about the best methods of birth control to use while taking Carim.

It is not known whether modafinil passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Carim is not approved for use by anyone younger than 17 years old.

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Nuclear abnormalities similar to those of topo IIalpha-depleted embryos were induced in HeLa cells in which topo IIalpha was knocked down by transfection with short interfering RNA (siRNA) against topo IIalpha, followed by induction of apoptosis. Health education for microcredit clients in Peru: a randomized controlled trial. Our results suggest that partial nephrectomy in the mouse establishes a model of uremic cardiomyopathy which shares phenotypical features with the rat model as well as patients with chronic renal failure. A dicopper complex chemiluminescence probe for the determination of thiols in the extracts of murine P388 lymphocytic leukemia cell. There is much in the literature on the regional distribution of physicians but far less is written about their pattern of movement. These data indicate that neither FVL nor PT G20210A is associated with RM prior to 10 weeks of gestation.

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Regulation of axon growth is a critical event in neuronal development. It is becoming clear that surface nanotopography of underlying substrates can influence cell behavior such as adhesion, proliferation, and orientation of mammalian cells. Catalytic mechanism of l,l-diaminopimelic acid with diaminopimelate epimerase by molecular docking simulations. The aim of this study was to assess the feasibility of symptomatic adverse events in hospice and palliative care and assessing their incidence. In vitro effect of subinhibitory concentrations of antibiotics on biofilm formation by clinical strains of Salmonella enterica serovar Typhimurium isolated in Slovakia. A case of acute bronchitis caused by Neisseria meningitidis associated with HIV infection. Based on the results, we conclude that under conditions of sustained, Poisson-like, weakly correlated, low to moderate levels of internal activity as found in the cortex, it is unlikely that recurrent cortical networks can robustly generate precise spike trajectories, that is, spatiotemporal patterns of spikes precise to the millisecond timescale. A mechanically durable liquid polyacrylamide-based matrix has been developed that, upon polymerization, facilitates the handling of one-dimensional and two-dimensional gels. Transfer of complex frontline anticancer therapy to a developing country: the St. However, unlike dysferlinopathy, none of the conventional membrane repair pathways are defective in these patient cells.

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Insulin release has no absolute requirement for extracellular monovalent ions. IMRT treatment plans were generated with and without SPECT guidance and compared for 5 patients. The peroxidase-antiperoxidase (PAP) immunohistochemical technique was used to identify neurons in the basolateral amygdaloid nucleus (BL) that contain vasoactive intestinal polypeptide (VIP), somatostatin (SOM) or cholecystokinin (CCK). Therefore, the inclusion of zeolites in algal cultures in aquaculture may have economic advantages. Randomized trials were included if they directly compared equiosmolar doses of hypertonic sodium solutions to mannitol for the treatment of elevated intracranial pressure in human subjects undergoing quantitative intracranial pressure measurement. The roles of healthcare professionals in implementing clinical prevention and population health. In general, the tissue-specific methylation is restricted to a part of the promoter CpG island, with hypomethylation of the remaining sequence. Much of these changing trends are caused by the recognition that the current method of resuscitation with crystalloid fluids may not be optimal and may even have detrimental consequences. The amount and accuracy of the information it provides far exceeds that produced by conventional radiographic techniques.

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Resistance to antimalarials in Southeast Asia and genetic polymorphisms in pfmdr1. In the first step, a neural network (NN)-based observer and a disturbance observer are designed to approximate the unknown nonlinear terms and estimate the input disturbances, respectively. Previous studies have reported larger myocardial perfusion defects with exercise as compared with dipyridamole. It is not widely appreciated that these distortions occur in predictable directions and that they may be of considerable magnitude, even when the gold standard has a high degree of accuracy. Surgery followed by poRT offers the best treatment strategy not only for advanced-stage lesions but also for high-grade adenocarcinomas, regardless of the stage of disease at presentation.

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