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Cardizem (Diltiazem)

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Cardizem is an antihypertensive and vasodilating agent that works by relaxing the vascular muscle and reducing blood pressure. This is related to the long-term therapeutic effects, as lowering the blood pressure reduces the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions.

Other names for this medication:
Altiazem, Angizem, Cardem, Cardiorex, Cartia, Coriem, Dicard, Dilacor, Dilcardia, Dilcontin, Dilcor, Dilgard, Dilocor, Dilter, Diltia, Diltiaz, Diltiazem, Dilticard, Diltime, Diltp, Dilzem, Heartil, Icidil, Ionozem, Kaizem, Masdil, Onzem, Taztia, Tiamate, Tiazac

Similar Products:
Zithromax, Zanaflex, Asacol, Bactrim, Cymbalta, Lunesta

Also known as: Diltiazem


{name} (diltiazem) is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels.

{name} is used to treat hypertension (high blood pressure). It may be used alone or in combination with other high blood pressure medications.

{name} is also used to treat chronic stable angina (chest pain) and angina due to coronary artery spasm.


This section provides information on the proper use of a number of products that contain diltiazem. It may not be specific to Cardizem LA. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended-release tablet, extended-release capsule, or tablet whole. Do not open, crush, or chew it. It is best to take the extended-release capsule on an empty stomach.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For chest pain: For oral dosage form (extended-release capsules): Adults—At first, 120 milligrams (mg) once a day in the morning. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 180 milligrams (mg) once a day, either in the morning or evening. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 30 milligrams (mg) four times a day before meals and at bedtime. Your doctor may increase your dose if needed. Children—Use and dose must be determined by your doctor.

For high blood pressure: For oral dosage form (extended-release capsules): Adults—At first, 180 to 240 milligrams (mg) once a day in the morning. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 180 to 240 milligrams (mg) once a day, either in the morning or at bedtime. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of diltiazem can be fatal.

Overdose symptoms may include slow heartbeat, weakness, chest pain, shortness of breath, or fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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This study demonstrates that neither MCP-1 nor its receptor CCR2 is required for the induction of oral tolerance. Conclusion: In Germany, use of WAI and the WPAI in as many early intervention approaches as possible will help improve the database, allowing better comparability. Fine-needle aspiration biopsy of solid aneurysmal bone cyst in the humerus. The Holliday junction is a central intermediate in homologous recombination. Spirometric and bronchospirometric functional changes during ultrasonic massage of the thorax. The aim of this study was to determine whether Ia and II fiber discharges of soleus muscle spindles were modified after a 14-day period of hypodynamia (absence of weight bearing) and hypokinesia (reduction of motor activity). Some general observations, potential mediators of spasm, role of calcium antagonists. RAW 264.7 cells, stably transfected to overexpress arginase I or beta-galactosidase, were treated with interferon-gamma to induce type 2 NO synthase or with lipopolysaccharide or 8-bromo-cAMP (8-BrcAMP) to induce ornithine decarboxylase. Effect of heavy water (2H2O) on regulatory properties of phosphoglucose isomerase from Lactobacillus casei. Complication rates appear to be comparable with the current standard endoscopic and percutaneous approaches to palliation of malignant strictures of the bile duct.

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Species identification of Malayan Gaur, Kedah-Kelantan and Bali cattle using polymerase chain reaction-restricted fragment length polymorphism. The effects of temperature on yeast growth and ethanol production were investigated in batch cultures. The decay of the first intermediate, a C(4a)-peroxyflavin, results in rupture of the oxygen-oxygen bond and is rate-determining in overall catalysis. Numerous useful methods for their preparation have been developed in recent years. Aberrant expression of miR-378 has been found in some types of cancer. Human proximal tubular epithelial cells were cold stored in University of Wisconsin (UW) solution for 48 h followed by 24 h of rewarming in regular cell culture medium. One of the authors, a recent recruit, provides a first-person account of his experience working within the collaboration. The participant was a 20-month-old girl with type II spinal muscular atrophy. We identified associations between cigarette smoking and a diverse range of metabolites.


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Short-course kidney-invigorating therapy improves near-term semen quality in asthenozoospermic men with kidney deficiency. The contribution of the scientific potential of the Military Medical Academy to solving the practical tasks of military medicine. Bilateral embolization is indicated when unilateral treatment does not result in detumescence of the penis. CHO cells in gel/medium were used for RBE determinations throughout the dose distributions. Mouse MSCs (mMSCs) microencapsulated in collagen were osteogenically differentiated to derive a bone-like matrix consisting of osteocalcin, osteopontin, and calcium deposits and secreted bone morphogenic protein 2 (BMP2). Reevaluation of conventional pituitary irradiation in the therapy of acromegaly. Patients followed in the lupus clinic over a 2-year period who had at least 3 visits and at least 18 months of followup were included. Evidence for natural existence of pyridinoline crosslink in collagen. Surgical treatment of cataract--indication and various surgical approaches. To determine the propensity of retinal proteins for spontaneous damage via formation of isoaspartyl sites, a common type of protein damage that could contribute to retinal disease.

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We have used whole-mount in situ hybridization to investigate the patterns of c-kit and Sl expression in stage 11-22 chicken embryos. Also, no difference existed between the variant cells and the parent cells in rates of attachment to the surfaces of plastic dishes or to monolayers of endothelial cells. A standardized register has comprised 292 patients with diabetes type 1 and 2 whose visual disability resulted from diabetes. Poor performance on CMD subscores was correlated with long disease duration and lengthening of visual and auditory RT and MT, with the motor speed subscore showing the highest correlations. Several techniques for spinal fusion are available and the optimal technique remains uncertain. Modeling results that take account of the geometry and phases of the cortical sources phase locked to the two streams (including hemispheric asymmetry of lPCS activity) help to explain why past ASSR bactrim ds iv dosing studies of auditory spatial attention yield seemingly contradictory results. The loss of relatives reduces the participant family adaptability. Community-acquired pneumonia in the elderly: Spanish multicentre study. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress.

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We investigated the activity and protein level of an antioxidant enzyme, Cu, Zn-superoxide dismutase (SOD) in alveolar macrophages (AMs) of patients with DPB before and after erythromycin therapy. Minimum number of lymph nodes that should be examined for the International Union Against Cancer/American Joint Committee on Cancer TNM classification of gastric carcinoma. Fast, Convenient, and Efficient Molybdenum-Catalyzed Asymmetric Allylic Alkylation under Noninert Conditions: An Example of Microwave-Promoted Fast Chemistry We gratefully acknowledge financial support from Personal Chemistry, the Swedish Natural Science Research Council (C.M.), and the Swedish Research Council for Engineering Sciences (M.L., A.H.). To explore how position influences development of otherwise similar photoreceptors, we analyzed the molecular characteristics of photoreceptors we discovered at the very anterior, the posttrochal mid-body and posterior body region of larval Leptochiton asellus, a representative of the chiton subgroup of mollusks. The child later presented at the age of two years with multiple radio-opaque shadows in the pelvis. One way to exclude sister strand exchange in meiotic recombination. Studies from developed countries recommend iron supplementation based on serum ferritin levels. The HIV-positive population receiving antiviral therapy may be an under-recognized group at risk for ergotism through decreased hepatic metabolism of ergot preparations. In all varieties of graft acceptance that do not require full-dose maintenance immunosuppression, immunological engagement of donor and recipient and an early unstable period have been observed. This study examined the treatment effects produced by 2 types of the Herbst appliance (acrylic splint and stainless-steel crown) followed by fixed appliances, and the pendulum appliance followed by fixed appliances.

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Thoracic CT is an important tool commonly used for breast cancer staging and surveillance and for diagnostic indications such as shortness of breath and chest pain. To describe transcendental meditation and review research on its use in the treatment and prevention of coronary heart disease. Race still matters: the disturbing persistence of racial disparities. An easy and reliable method for single or multiple preparations. Dex alone kills these cells, though only after a delay of at least 24 hours.

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The border of osteopenia and osteoporosis is demarcated by -2.5 SD (T-score) in adults, while in children the most proper is considered to be -2.0 SD (Z-Score). From cyproheptadine 4 mg tablet para que sirve these data, we conclude that Ang II negatively regulates the insulin signal, Akt, in the vasculature specifically through PKC-alpha activation, providing an alternative molecular mechanism that may explain the association of hyperinsulinemia with cardiovascular diseases. Use of cerebellar brain smears in the diagnosis of babesiosis (Babesia bovis) in cattle. Multiple fractures of the ribs associated with subdural hematoma in a premature infant. Death, dying and emotional labour: problematic dimensions of the bone marrow transplant nursing role?.

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(18)F-FLT PET was performed at baseline and at interim (iPET) after 1-2 cycles of therapy. Prevalence and clinical impact of QRS duration in patients with low-flow/low-gradient aortic stenosis due to left ventricular systolic dysfunction. Seminal vesicle cyst associated with renal agenesis and ipsilateral ectopic ureter. Chronic administration of nicotine enhances NMDA-activated currents in the prefrontal cortex and core part of the nucleus accumbens of rats. The results support recent views of human inference that postulate that lay hypothesis testers are sensitive to the rarity of data. Effect of home mechanical in-exsufflation on hospitalisation and life-style in neuromuscular disease: a pilot study. In this study, three batches of fluoropolymer-coated canisters were investigated by electrochemical impedance spectroscopy (EIS) and scanning electron microscopy (SEM). Positive staining of tumor was observed in 28 tumors (23 invasive and/or metastatic thymomas, two thymic carcinomas, and three non-invasive thymomas). Severe relapsing sulphonylurea-induced hypoglycaemia: a diagnostic and therapeutic challenge. In addition to the standard test, it is also now possible to analyze milk metabolites in a high-throughput manner and to consider them in connection with milk traits to identify functionally important metabolites that can also serve as biomarker candidates.

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Thus, this study aimed to investigate the relationship between circulating total and differential leukocyte counts including N/L ratio with urinary protein and albumin excretion in patients with newly diagnosed type 2 diabetes. Postal questionnaires were sent to all Swiss paediatricians to assess their current practice for treating acute bronchiolitis in children. Complicated hydatid cyst and differential diagnosis of lung diseases. In addition, a significant translocation of PI3-kinase to the nucleus was observed after C2-ceramide treatment. A longer duration of the preoperative treatment might be associated with a longer progression-free survival. Effects of estradiol and estradiol sulfamate on the uterus of ovariectomized or ovariectomized and hypophysectomized rats. To verify the feasibility and safety in humans, the authors attempted remote robot-assisted laparoscopic cholecystectomy on a 68-year-old woman with a history of abdominal pain and cholelithiasis. A novel method has been developed for the activity measurement of large-area beta reference sources. The loops open at velocities that are much faster than those seen in nonoverheated films. Characterization of purinergic receptors and receptor-channels expressed in anterior pituitary cells.

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Treatment has advanced significantly in the recent past and there has been improved patient survival. Cuticular hydrocarbons and novel alkenediol iacetates from wheat stem sawfly (Cephus cinctus): natural oxidation to pheromone components. Preliminary results indicated the degradation of EGFR might plavix generic name be regulated by ubiquitin level. Therefore, radiological analyses are considered the most appropriate method. The current research explores racial categorization further by using two sets of participants: those with greater experience of White faces and those with greater experience of Black faces. We used the automatic DNA sequencing machine (Model 377) to detect the nucleotide sequence of the inserted part of the recombinant plasmid pBX1 from Borrelia burgdorferi B31 strain.

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Cyproheptadine for prevention of neuropsychiatric adverse effects of efavirenz: a randomized clinical trial. Evaluation of the micro enzyme-linked immunosorbent assay for antibodies to Trypanosoma cruzi. Between 0-36 h there were progressive increases in serum concentrations of LH and FSH, enhanced accumulation of estradiol by individual follicles incubated in vitro with or without exogenous substrate, and marked progressive increases in the content of LH (but not FSH) receptors in both thecal and granulosa cells. Two males were also studied to investigate the possible existence of cyclic change of corneal thickness in females vs males. We examined the effects of infant age and gender on the behaviors of infants and mothers during discipline interactions using longitudinal, naturalistic, home-based, taped observations of 16 mother-infant dyads (eight males and eight females). Moreover, estradiol administered to the retrochiasmatic area in ovariectomized anestrous ewes inhibits LH secretion. The probability albenza 200 mg price of ever marrying and the conditional probability of marriage in a given time period were lower for smaller men and greater for larger men. In the young age bracket, incidences of SLD in distal radius fractures were significantly higher than in normal wrists. Although not common, infections involving C tertium can produce severe, potentially life- and limb-threatening disease processes, which may require aggressive therapy even in the nonimmunocompromised patient.

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We provide novel data demonstrating that alcohol consumption reduces rates of MPS following a bout of concurrent exercise, even when co-ingested with protein. Paradoxical glucose-induced hyperkalemia (GIH) was elicited exclusively in the upright position during captopril treatment in four hypertensive patients (Group 3) without impaired glucose tolerance in three. Special interest needs to be taken in patients admitted to cardiac surgical intensive care units, as these patients are at high risk for infections, particularly nosocomial pneumonia, catheter-related and wound infections. The cells are arranged in a regular mosaic pattern of single and twin cones as in many fishes, and this arrangement suggests that the different cone types also show different spectral sensitivity, which is the basis for colour vision. UV-induced G2 checkpoint activation in this situation therefore relies on signalling via the p38 MAPK and ATR-Chk1 signalling cascades. The data, gathered in a dedicated database, were processed by applying univariate and multivariate analysis models.

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An electron-microscopic study of the early outgrowth from chick spinal cord in vitro. Correlation of clinical and morphological aspects of multiple spongioblastomas. Onset neurons can also entrain to higher frequency stimuli than sustained neurons. Here we used antibody competition analysis to examine the structural changes that occurred in the SHIV-HXBc2P 3.2 gp120 exterior envelope glycoprotein. H-RN has anti-angiogenic activity in HUVECs and in a mouse model of what is the best brand of valium VEGF-induced corneal neovascularization. Eleven patients with traumatic root avulsions of the brachial plexus were studied. In adults it is well documented that there are substantial losses to the programme between HIV testing and start of antiretroviral therapy (ART). Radiologic analysis showed statistically significant angular deformity in the laminectomy group compared with laminoplasty and control groups at 3 months. A screen for candidates revealed suppressor of cytokine signaling 2 (SOCS2), an inhibitor of growth hormone (GH) signaling, was strongly induced after partial hepatectomy.

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