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Cardiosol (Nifedipine)
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Cardiosol

Cardiosol is a calcium-channel blocker. It affects the amount of calcium found in your heart and muscle cells. This relaxes your blood vessels, which can reduce the amount of work the heart has to do. This medicine is used to treat chest pain caused by angina.

Other names for this medication:
Adalate, Addos, Adipine, Afeditab, Antrolin, Atanaal, Cardipin, Conducil, Coral, Depicor, Depin, Fedip, Glopir, Hexadilat, Hypan, Menoprizin, Nidicard, Nifangin, Nifcal, Nifecap, Nifecard, Nifeclair, Nifedel, Nifediac, Nifedine, Nifelong, Nipin, Ospocard, Sepamit

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Also known as: Nifedipine

Description

Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Cardiosol. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Cardiosol and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Cardiosol dosage information

Side effects

The most common side effects associated with Cardiosol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

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Hypothalamic gene expression during voluntary hypophagia in the Sprague-Dawley rat on withdrawal of the palatable liquid diet, Ensure. Acute situations in the dental chair: patient who does not respond well. We investigated SLE patients who developed PRES between 2005-2011 at the Universiti Kebangsaan Malaysia Medical Centre. In particular, communicable and non-communicable diseases, including cancer, have been considered. conorii was demonstrated in HUVECs, THP-1 cells (human macrophages), and human peripheral blood monocytes activated with the cytokines. Peptide-tethered monodentate and chelating histidylidene metal complexes: synthesis and application in catalytic hydrosilylation.

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Biochemical markers, including hs-CRP and PAB values, were measured. The characteristics and difference between RWS and EBM, and the situation of acupuncture clinical research methods are discussed in this paper. Inasmuch that LC-MS/MS is a method of choice for foodstuffs monitoring of organic contaminations, due to its routine quantitative analytical procedures, it is often characterized with the difficulties of the chromatographic separation of the closely structured analytes at a large scale of experimental conditions, complex multi-step sampling pretreatments, which inevitably alert the variables through the systematic and random errors. In this work we exploit such technique to characterize bacterial systems. In current food packaging, these nanomaterials are primarily used to impart antimicrobial function and to improve barrier properties, thereby extending the shelf life and freshness of packaged food. The present study compared 5 qRT-PCR assays, including 2 commercially available kits, for the detection of BTV in semen serially collected from 8 bulls over a period of 90 days after experimental infection. We present a case of accidental, intra-operatively diagnosed neuroendocrine-active sympathetic paraganglioma, which was suspected and confirmed during elective retroperitoneal tumor removal. Predicting cardiac surgery-associated acute kidney injury: The CRATE score.

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The octave effect is explained in terms of the fact that the spectrum of frequencies of speech sounds, singing and music coincides with the region of the audibility range in which the impulses of the auditory nerve fibers are synchronized by incoming signals. This circadian system weakness permits the occurrence of a very strong ultradian component, modulating sleep/wake rhythm. The response to epinephrine was antagonized in a concentration dependent manner by bupranolol, and Schild plot of the data revealed the pA2 value of 5.87. A double-blind, multicenter clinical trial of acyclovir vs idoxuridine for treatment of epithelial herpes simplex keratitis. We aimed to rapidly review evidence on key stakeholder (patients, their proxy decision-makers, clinicians and regulators) views concerning the acceptability of various approaches for obtaining consent relevant to pandemic-related acute illness research. These results indicate that rare genetic variation in the CHRNA5-A3-B4 gene cluster contributes modestly to the LR to alcohol in the San Diego Sibling Pair study and may protect against AUDs. Sweat chloride concentration in children with allergy and with cystic fibrosis of the pancreas. The methods to identify key regions determining subpocket specificity introduced in this study are directly applicable to other serine proteases, and the results provide starting points for new strategies in rational drug design. With every 1 percent increase in the unemployment rate, recertification candidates demonstrated a greater loss of cosmetic cases relative to primary candidates and an accelerated decline in reconstructive cases starting in 2007. trifolii wild-type Rt24.2 and the Rt2472 mutant identified a set of genes belonging to the RosR regulon and confirmed the important role of RosR in the regulatory network.

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Since angiogenesis is essential for tumor progression and metastasis, we herein investigated the anti-angiogenic effects of the compound. More than 800 primary studies not included in a systematic review and 107 systematic reviews were included. Reticulocyte cellular indices such as MCVr (mean reticulocyte volume), CHr (reticulocyte hemoglobin content), CHCMr (reticulocyte hemoglobin concentration) entered recently in few automated reticulocyte counters allows for assessment of the functional state of the erythropoiesis in the diagnosis and monitoring of the iron deficiency and rhEpo therapy. Oncogenic Kras activates a plethora of signaling pathways, but our understanding of critical Ras effectors is still very limited. Downregulation of connective tissue growth factor reduces migration and invasiveness of osteosarcoma cells. The charts were reviewed to determine demographic variables, the surgical procedures performed, prior operations, the rhinoplasty approach used, and the graft donor and recipient sites. The degree of crizotinib resistance correlated with autophagic activity. Some data on the quality of scattered radiations during roentgenological examination. In TLE patients with a hippocampal epileptic focus, we demonstrated a specific deficiency of complex I of the mitochondrial respiratory chain in the hippocampal CA3 region. In order to investigate the mechanical mechanism and the haemodynamic validity of the bypassing treatment for DeBakey III aortic dissection, patient-specific models of DeBakey III aortic dissection treated with different bypassing strategies were constructed.

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Modification of a spectrophotometric method of determining prometryne for microbiological studies. New devices: suction equipment set, a nebulizer tent, use of a copper wire for better fitted respirator masks and nebulizers used in tracheostomy, and a fixed temperature water bath. In comparison to traditional distance-based methods, quartet-based methods consider more information in the reconstruction process and thus have the potential to be more accurate. None of these is considerably more susceptible to a virulent strain of the bacterial pathogen Pseudomonas syringae pv. Classification of canine nonangiogenic, nonlymphogenic, gastrointestinal sarcomas based on microscopic, immunohistochemical, and molecular characteristics. Therefore, Tim-1-Fc might be a potential immunosuppressive agent in the setting of cardiac transplantation. Fluorescence microscopy studies using the fusion protein of GCRP with green fluorescence protein (GFP) indicated that GCRP was present in the cytosol in PC12 cells, but translocated toward the plasma membrane in the presence of ANF. Methods of mortality risk adjustment in the NICU: a 20-year review. We suggest that serum creatine phosphokinase should be monitored in DF patients to allow for an early diagnosis of rhabdomyolysis and the institution of renal protective measures. Functional RNAs, such as microRNA (miRNA) and mRNA, are present in milk, but their roles are unknown.

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Therefore, until a curative treatment has been developed, the available repertoire of immunosuppressive or immunomodulatory treatments should be assessed with respect to the possibility of long-term use. Mean pulmonary arterial pressure (mPAP) was measured by a right cardiac catheterization, and mean systemic blood pressure (mSBP) was measured by left femoral catheterization. Due to its scarcity, little is known about the ecology, biology, and development of this peculiar species. Immunological detection and quantification of the reaction products of 2-acetylaminofluorene with guanine in DNA. Also, the graft must be obtained and stored in aseptic and atraumatic conditions. The decrease in steady-state level of these mRNA transcripts results, in part, from decreased mRNA stability in Bcl-2-deficient chondrocytes.

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Diffuse pagetoid squamous cell carcinoma of the esophagus combined with choriocarcinoma and mucoepidermoid carcinoma: an autopsy case report. In both groups 8 rats were killed 1, 3, and 7 days after the induction of gastric ulcer by acetic acid respectively. Also, for a given load dependence, relaxation will be affected by changes in the conditions of load, which are complex in the whole heart (return force, end systolic deformation, arterial impedence, the law of Laplace, increased intra myocardial pressure due to rapid filling of the coronary reservoir). To identify the downstream targets of PI3K involved in Ang II-induced proliferation, we used both rat aortic smooth muscle (RASM) cells and a CHO cell line stably expressing the rat AT1A receptor. NO2-FAs are engaged in posttranslational modifications (PTMs) of a selective redox sensitive pool of proteins and regulate key adaptive signaling pathways involved in cellular homeostasis and inflammatory response. Introduction to commercially approved customized ablation: tenth year in review. This was a retrospective study of all singleton pregnancies referred to a tertiary care referral hospital with a femur length below the 5(th) percentile. Reactivity of the ammonium carbamate self-derivative salt is further illustrated by the observation of a series of derived products, including dehydroprolinamide, a methylene-bridged prolinamide, and a bicyclic derivative. Of 696 patients treated with everolimus as second targeted therapy, 605 patients received first targeted therapy with sunitinib/sorafenib and 91 with pazopanib. The 2 examined group were distinguished: the 1-st-42 cases of cervical carcinoma in Ib1 stage and the 2-nd-21 cases of Ib2 staged carcinoma.

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Finally, we will discuss potential future advancements in this area, which include the development of hand-held devices containing miniature proteomic and metabolic assays which can be used for facilitating diagnoses in a point-of-care setting and yield results in less than 15 minutes from a single drop of blood. Bone morphogenetic proteins (BMPs) are multifunctional growth factors regulating differentiation and proliferation in numerous systems including the immune system. To study the adverse effects of Celecoxib and compare them with those of other non-steroidal anti-inflammatory drugs (NSAIDs) in an Asian Indian cohort. Identification of cell-binding sites on the Laminin alpha 5 N-terminal domain by site-directed mutagenesis. Restrictions on the coverage of abortion and contraceptives in abortion settings prevent the initiation of desired long-acting methods. In order to visualize what Lake Michigan mottled sculpin might perceive through their lateral line when approaching prey, we have combined anatomical, neurophysiological, behavioural and computational modelling techniques to produce three-dimensional maps of how excitation patterns along the lateral line sensory surface change as sculpin approach a vibrating sphere. Thus, the isolated TFTC-type HAT complex acts as a third class of coactivator complex for NR function.

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Morphology and minimum ADC would be useful in distinguishing breast cancer subtypes. Hirsutism and AN are the most reliable cutaneous markers of PCOS and require a comprehensive skin examination to diagnose. A mutation in COL4A2 causes autosomal dominant porencephaly with cataracts. A 21-year-old female patient came to our outpatient department with depressive symptoms and suicidal thoughts. Prostacyclin might be of threapeutic interest in attacks of angina pectoris precipitated by redution of oxygen delivery to the myocardium rather than increased oxygen demand. The urethra-cancer distance was correlated with the clinical, pathologic, and laboratory factors. Doxorubicin-enhanced skin reaction after whole-body electron-beam irradiation for leukemia cutis. Blood was sampled before and during a 30-minute signal which ended with food availability and before and during a 30-minute signal which was not closely and reliably linked with food availability.

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Serologic and clinical evidence for endemic occurrences of human granulocytic ehrlichiosis in North-Eastern Switzerland. This study is the first identification of a cellular process whose regulation appears to be associated with SULT4A1 expression. The results were compared with those of a control group consisting of 127 HIV-negative women in pre-menopause age. The pathological patterns with some consideration on clinical features are summarized, compared with those of the how much does rhinocort cost corresponding human diseases. The larvae were obtained from onboard hatching of brooding females (either at atmospheric pressure or at habitat pressure in hyperbaric chambers) and from the water column near adult habitats, sampled with plankton pumps or sediment traps. Although bilirubin bound to the primary binding site has attracted the most attention, the presented results have documented the impact of the secondary binding sites which are relevant in the displacement reactions between BR and drugs and in the phenomena where bilirubin plays antioxidant, antimutagenic, and anti-inflammatory roles. Identification and characterization of MKK7 as an upstream activator of JNK in Litopenaeus vannamei. We reveal that PlGF is produced in the cerebellar stroma via tumor-derived Sonic hedgehog (Shh) and show that PlGF acts through Nrp1-and not vascular endothelial growth factor receptor 1-to promote tumor cell survival. The specific route and timing of human herpesvirus (HHV) 8 infection in regions where Kaposi sarcoma is endemic are not known.

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The system is based on co-transfection of candidate enhancer elements and reporter constructs into Swarm rat chondrosarcoma chondrocytes that retain a high level of aggrecan expression. Performance and adaptive value of tarsal morphology in rove beetles of the genus Stenus (Coleoptera, Staphylinidae). Deoxycorticosteron acetate-induced hypertensive WKY also showed decreased TM levels compared with normotensive WKY. The 10th and 85th percentiles of weight-for-stature at selected ages were also reexpressed as BMI-for-age percentiles. Mapping the dynamics of brain perfusion using functional ultrasound in a rat model of transient middle cerebral artery occlusion. Thickening and microscopically signs of inflammation were observed in hydrocortisone-exposed membranes but not phenergan gel sig in dexamethasone-exposed membranes, which did not differ morphologically from those in control ears.

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