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Calcigard (Nifedipine)

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Calcigard belongs to the group of Calcium Channel Broker (CCB). This medication is used to control chest pain (angina) and hyper tension (high blood pressure). Calcigard was produced by Bayer, a reputed German pharmaceutical company. The initial studies on the drug were undertaken in the year of 1970. This drug is approved by FDA.

Other names for this medication:
Addos, Adefin, Atanaal, Calcibloc, Cardicon, Cardiosol, Cobalat, Conetrin, Cordalat, Cordipin, Depicor, Depine, Epilat, Fedip, Ficard, Menoprizin, Nidilat, Nidipine, Nifcal, Nifebene, Nifecardia, Nifedate, Nifedigel, Nifedine, Nifedipin, Nifedipinum, Nifedipress, Nifelat, Nifelong, Nycopin, Nyefax, Pabalat, Pressolat, Sepamit, Vasdalat

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Calcigard PA 10. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Calcigard and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Calcigard are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Subjects completed interview and self-report assessments of depressive symptoms and social adjustment every 4 weeks. Few large epidemiologic studies have investigated the role of postweaning protein intake in excess weight and adiposity of young children, despite children in the United Kingdom consistently consuming protein in excess of their physiologic requirements. It exhibits a wide range of biological effects, including preventative effects against heart attack and stroke, and the induction of apoptosis in various cancer cells. Effects of Long-Term Video-electroencephalographic Monitoring on Mood in Epilepsy Patients. The model helped us to study the kind and magnitude of errors that arise from quantitative and semiquantitative competitive PCR protocols and to find ways to minimize them. Electronic device for the determination of the rate of reflex reactions simultaneously in several subjects.

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Controversy continues to surround the issue of the relationship between postmenopausal hormone therapy and the risk of breast cancer. Rabies encephalitis: management in a district general hospital ICU. Here we review the current state of information about the functions of the COX-specific gene products and of their relationship to human COX deficiencies. These movements initially consisted of myoclonic twitches of the paravertebral muscles close to the injection site, repeated tonic and clonic contractions and extensions of the hind limbs (hind limb seizures) that spread to the fore limbs, and finally rotational axial movements of the body. The acids were only moderately toxic for the coliform strains under the same conditions. Medical care and privileges of the physician reflecting the social stratification. The determination of house dust mite and cat allergens is a prerequisite for qualified assessment of exposure risk indoors. Hydroxylation of the difluoro and tetrafluoro derivatives liberated stoichiometric amounts of fluoride.

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CPR must be interrupted for a reliable automated rhythm analysis because chest compressions induce artifacts in the ECG. Further history revealed significant cardiovascular risk factors, examination showed an evidence of hyperlipidaemia and investigations revealed acute pancreatitis secondary to hypertriglyceridaemia. At the end of the implantation time, the implants were retrieved, embedded, and processed for histology. Activation of Helicobacter pylori CagA by tyrosine phosphorylation is essential for dephosphorylation of host cell proteins in gastric epithelial cells. The pseudohypoparathyroidism type lb locus is linked to a region including GNAS1 at 20q13.3. Role of a novel soluble nucleotide phospho-hydrolase from sheep plasma in inhibition of platelet reactivity: hemostasis, thrombosis, and vascular biology.

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The necessity for lifelong follow-up in long-term survivors of SCLC is emphasized. This study try to detect the microvessel density of tumor tissues and micrometastases of regional lymph nodes in ovarian cancer and to investigate the relationship between these two factors and their prognostic significance. To evaluate the prevalence of human herpesviruses (HHV) 1-6 and community-acquired respiratory viruses (CARVs) in specimens from patients with nasal polyposis undergoing functional endoscopic sinus surgery (FESS) and investigate the potential clinical role. Evaluation of perioperative psychological response to short-stay hospital surgery. Normal diet was given to the patients in control group under the same condition as those in EN group in terms of calories and nitrogen contents. State of undergraduate education in emergency medicine: a national survey of clerkship directors. This is the first report of surgery and definitive radiation therapy for curative intent therapy of extramedullary penile plasmacytoma in a dog.

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Highlights of the history of the Rudolf Virchow Medical Society. These data suggest that diabetes is associated with periodic breathing, a respiratory abnormality associated with abnormalities in the central control of ventilation. Resting-state functional connectivity MRI (rs-fcMRI) may provide insight into the neurophysiology of HIV and aging. Effect of mineral salts on optic density of solution in colorimetric determination mannosidostreptomycin using the anthrone method. A systematic literature review through Pubmed and Medline was performed to find the studies on this topic, and all controlled clinical trials, case reports, and case series were reviewed. MRI findings were suggestive of myelin damage with symmetrical involvement of the cerebellar hemispheres and, to a lesser extent, the decussation of the superior cerebellar peduncles, the corticospinal tracts and the centrum semiovale. Myocardial blood-flow response during mental stress in patients with coronary artery disease. In contrast, the incidence rates of medulloblastomas and ependymal tumors decreased.

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Tritiated amino acids injected in the abducens nucleus (Abd N) labeled: (1) root fibers ipsilaterally, and (2) fibers that ascended in medial parts of the contralateral medial longitudinal fasciculus (MLF). Because of the similarity in their cytoplasmic domains, IL-1/Toll receptors share signaling components that associate with the IL-1 receptor, including IL-1 receptor-associated kinase (IRAK), MyD88, and TRAF6. Whole body protein turnover in critically ill patients with multiple organ failure. Regularization based on the distribution area and on its second derivative are compared and assessed along with the following techniques for selecting the optimal regularization parameter: the L-curve method, generalized cross validation (GCV), and the discrepancy principle. The effect of femoral stem size on failure rates in total hip replacement cemented with Boneloc. This investigation was a retrospective study of sural neuropathy at a single electrodiagnostic center. We show, applying ROC (receiver operating characteristics) to binary classification of a large sample of self-declared synaesthetes and non-synaesthetes, that the consistency criterion (i.e., cut-off value) for diagnosing synaesthesia is considerably higher than the current standard in the field. Electrophoretic behavior of total serum proteins before and after operations for non-neoplastic diseases of the digestive apparatus. No noteworthy complaints could be recorded even 16 years after the operation. For the purpose of clarifying the influence of HA4 on ceramide synthesis, we evaluated both of these factors in keratinocytes in vitro and in vivo.

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Coagulation volume, sphericity, and mean short-axis diameter were assessed, and mathematical functions were fitted for each system and assessed with the coefficient of determination (R(2)). Proper site preparation and electrode application are essential to ensure adequate contact and to reduce the risk of burns. Stability and nickel binding properties of peptides designed as scaffolds for the stabilization of Ni(II)-Fe(4)S(4) bridged assemblies. Our data suggest that our method appears appropriate and useful for practical clinical purposes, furnishing an additional tool for investigating the physiological function of small-fiber pathways. These nocturnal respiratory disorders observed in amyotropic lateral sclerosis are similar to those observed in muscle diseases. Striae distensae fibroblasts contract collagen gels slower than normal human fibroblasts but the final contraction is similar. Suppression of endogenous PG biosynthesis leads to potentiation of LH-stimulated T production in vitro but is without effect on basal T output. Long-acting calcium channel blocker benidipine suppresses expression of angiogenic growth factors and prevents cardiac remodelling in a Type II diabetic rat model. The biggest obstacle preventing this in industrial production is that cephalosporin acylase uses glutaryl-7ACA as a primary substrate and has low substrate specificity for CPC.

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Attempted weight loss is associated with lower all-cause mortality, independent of weight change. Newborn nursery of a 30-bed obstetric unit in an urban university hospital. Using chronic catheterization techniques, we measured systemic cardiac power output (PO(sys)), systemic cardiac output (Q(.)(sys)), heart rate (fh), systemic stroke volume (V(s,sys)), systemic resistance (R(sys)) and mean arterial pressure (P(sys)) in red-eared sliders (Trachemys scripta). Cathepsin D and nm23 are two of the factors, investigated recently that have effects on invasion and metastasis of malign tumors. An association of increased MD with epilepsy duration was seen in the left hippocampus in left TLE. Central nervous system and spinal tuberculosis in children at a tertiary care center in Saudi Arabia. A simplified procedure for determination of urinary dehydroepiandrosterone. The dose of indomethacin was 50 mg for the first 5 days and 100 mg for the second 5 days. It has been used effectively to treat strabismus, dystonias and other movement disorders, and spasticity.

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Using the TG times, the TG-50 (the time required for one-half of the total number of the treated tumours to reach the volume of 800 mm(3) from 65 mm(3)) was calculated. A survey of 1,445 HIV-infected Medicaid recipients in New York State between April 1996 and March 1997. Poor compliance with postmolar surveillance and treatment protocols by indigent women. Is it too late to turn back the clock on managerialism and neoliberalism?. The products of these genes are likely to play fundamental roles in cellular processes. The infection of maize by Fusarium verticillioides can result in highly variable disease symptoms ranging from asymptomatic plants to severe rotting and wilting.

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KLH, therefore, may be a good candidate for an anticancer agent alone or in combination with other chemotherapeutic agents. Whole body MRI-DWI demonstrated regression of most of tumor lesions except one -marginally enlarged iliac lymph node and allowed to predict tumor progression in this particular anatomical site based on low ADC value after treatment. Regional birth data were obtained and a special care nursery survey was conducted. The results of this work demonstrated that the newly-developed strategy was efficient, repeatable, and could have good potential to be employed for detailed analysis of PHA monomeric composition. Specification of the recommendations of the German Coalition for Patient Safety (APS) for users and operators of anaesthesia equipment, explore opportunities and challenges for the safe use and organisation of anaesthesia devices. Studies on acid formation by saccharolytic, saprophytic Neisseria. The ability of biofilm formation in clinical isolates selegiline depression reviews of Acinetobacter baumannii belonging to two different European clones causing outbreaks in the Split University Hospital, Croatia. To analyze the effect of intensified topical steroid therapy after Descemet membrane endothelial keratoplasty combined with cataract surgery (triple-DMEK) on the incidence of postoperative cystoid macular edema (CME). Palmitate-induced activation of the hexosamine pathway in human myotubes: increased expression of glutamine:fructose-6-phosphate aminotransferase.

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Although both periodontitis and telomere length are age-dependent, they do not appear to be linked, suggesting that determination of leucocyte telomere length may not be a promising clinical approach at this age for identifying people who are at risk for periodontitis. The excretion of biotrace elements using the multitracer technique in tumour-bearing mice. As part of an ethnographic study to explore the culture of the school, 22 teachers took part in in-depth, semi-structured interviews to ascertain their views and experiences of teaching. Intraductal RFA, via both endoscopic and percutaneous approaches, is feasible. We found that tree architecture, number of nests per tree, and nest-specific characteristics were the main variables driving nest placement. After histological confirmation, they were classified using the rASRM and Enzian systems.

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Autoradiography of Ca45 in ashed sections of frog skeletal muscle. Influence of the number of layers on the equilibrium of a granular packing. Comparative studies of small doses of acelysin and low molecular weight heparin enoxaparine (clexane). PRQFVa is expressed in some of the neurons within the feeding circuitry and application of synthetic PRQFVa was found to decrease the excitability of some (B4/5 and B31/32) but not all (B8) neurons of the buccal feeding circuit. Short-chain carboxylic acids produced by Candida albicans in glucose supplemented batch cultures and in human denture plaque has been qualitatively and quantitatively analysed using isotachophoresis. EEG has constant and reproductible patterns in normal very premature infants. The interglobular spaces in the endochondral layer of the osseous labyrinth. Uremia and chronic kidney disease: the role of the gut microflora and therapies with pro- and prebiotics. Qualitative data from the survey were transcribed verbatim and categorised into themes using thematic analysis. Palliative stenting of the digestive tract: a case series of a single centre.

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As local anaesthetics may exert anti-inflammatory actions through their inhibition of nervous reflexes, we have studied the local effects of a single rectal dose of ropivacaine gel on rectal concentrations of eicosanoids and neurotransmittors in patients with relapsing ulcerative colitis. The American Journal of Gastroenterology celebrates the Golden Anniversary of the College. On the difference between pinocytosis and phagocytosis (on the example of Amoeba proteus). The aim of this study was to evaluate whether repetitive measurements of plasma levels of neurohumoral factors and cytokines before and after additional treatment are useful for predicting mortality in patients with congestive heart failure (CHF). Use of the RRS was associated with increased likelihood of dying in the preferred place. Computer Optimization of Biodegradable Nanoparticles Fabricated by Dispersion Polymerization. Long term safety studies are required to evaluate the incidence of adverse events. New method of studying the precursor-product relationship between high molecular weight RNA and messenger RNA. The protective associations did not change after adjustment for an extensive list of confounders or in the sensitivity analyses.

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The participants collected urine every 4 hrs, and cortisol concentration was determined. We achieve video-rate images by galvanometric scanning of the phase tilt at the proximal end. The effect of age and movement speed on maximum forward reach from an elevated surface: a study in healthy women. A comparison of the results obtained by this electron microscopic technique with Fc-reacting factor detection results obtained with hydrochloric acid extracts of cells in passive haemagglutination on sensitized red cells, showed that not only hydrochloric acid extractable but also non-extractable Fc-reacting factor can be present on the group A Streptococcus cell. Broadening index, detection index, characteristics of densitometric band, modified contrast index, limit of can you consume alcohol while taking tramadol detection, densitometric visualizing index, and linearity range of detected compounds were used for the evaluation of visualizing effects of applied visualizing reagents.

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Non-Abelian SU(2) Lattice Gauge Theories in Superconducting Circuits. None of these differences were considered treatment related, adverse, or biologically meaningful. Evidence for an Antibiotics-First Strategy for Uncomplicated Appendicitis in Adults: A Systematic Review and Gap Analysis. It is associated with increased oxidative stress and impaired ischemia-induced neovascularization. The diagnosis of POEMS syndrome is made with three of the major criteria, two of which must include polyradiculoneuropathy and clonal PCD, and at least one of the minor criteria. T-shaped angioplasty with apex puncture of thrombosed looped hemodialysis grafts. Quantitative gene expression of TGF-beta1, IL-10, TNF-alpha and Fas Ligand in renal cortex and medulla. Smoke-free homes can help protect children from tobacco smoke exposure (TSE).

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The standard sleep parameters obtained from night polysomnography as well as skin-fat fold thickness and neck circumference and maximum claritin dosage waist-to-hip ratio were analysed. Vitamin A status of pre-school children in Ibadan (South West Nigeria), risk factors and comparison of methods of diagnosis. Prediction and comparison of downlink electric-field and uplink localised SAR values for realistic indoor wireless planning. Differences between people in the training context challenge previously held notions, distribute authority in the group and foster open ended learning that enriches the activities of clinical supervision. The goal of this paper is to provide models of translational research based on the current evidence of promising botanicals with a specific focus on targeted therapies for PCa chemoprevention. This retrospective analysis evaluates 10 patients with a late infection of a cemented total hip arthroplasty (THA) treated with two-stage revision with retention of the original well-fixed femoral cement mantle. Further observations on the pathomechanism of leukocyte movements after injection of bacterial irritants. Chloroquinoxaline sulfonamide (chlorosulfaquinoxaline, CQS, NSC 339004) is active against murine and human solid tumors. On the first postoperative night, the breathing pattern was studied with a new noninvasive monitoring device measuring respiratory frequency and apnea. To Sink the Lifted: Selection, Technique, and Result of Laparoscopic Diaphragmatic Plication for Paralysis or Eventration.

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These results suggest that sex chromosome effects on neurodegeneration in the CNS run counter to effects on immune responses, and may bear relevance to the clinical enigma of greater MS susceptibility in women but faster disability progression in men. Measurement of drain fluid cytokines and MMP has the potential to diagnose colorectal anastomotic leakage at a preclinical stage, but is not yet ready for clinical use. Destiny of high-risk newborn infants subjected to respiratory resuscitation with an automatic ventilator. CBT should be considered as the first choice in patients with epilepsy. This reaction is complementary to the existing methods and is well tolerable with a variety of functional groups and readily scaled-up to a gram scale without deteriorating the yield. A catalytic multicomponent coupling reaction for the enantioselective synthesis of spiroacetals.

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We conclude that both media are a significant advance over the conventional ionic media and the choice between them will be determined by factors of neurotoxicity, ease of use and cost. pylori-associated gastritis is more prevalent when the density of infecting bacteria is high and when cagA positive strains cause the infection. Comparative acid-labile surfactant/sodium dodecyl sulfate two-dimensional (ALS/SDS 2-D)-PAGE experiments of lower abundant proteins from the proteomes of regenerating rat retina and mouse brain show that peptide recovery for mass spectrometry (MS) mapping is significantly enhanced using ALS leading to more successful database searches. Optimizing target coverage by dosimetric feedback during prostate brachytherapy. The synthesis is based on a seeded-growth tofranil drug classification approach based the rapid overgrowth of ultrathin gold wires in N,N-dimethylformamide, in the presence of poly(vinylpyrrolidone).

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Thus benefits include better therapeutic turnaround times, decreased blood loss as a result of reduced phlebotomy secondary to clinical improvement, and diminished resource utilization. Significant opportunities exist for quality improvement, novel educational strategies, and assessment of reasons why MDs and, to a lesser extent, RNs fail to follow simple HW practices. Is exercise-induced muscle damage susceptibility body segment dependent?. In 73 ICAD first-ever stroke patients, ankle-brachial index (ABI) was assessed three months after TIA or stroke together with CRP, Lp-PLA2, ICAM-1, E-selectin and PAI-1 measurements. Rheumatoid arthritis, spondylarthritis ankylopoietica and vocal infections in acute anterior uveitis. First isolation of the enterohaemorrhagic Escherichia coli O145:H- from cattle in feedlot in Argentina. Crude and adjusted odds ratios were calculated between men who scored 50 and above (childbirth fear) and those that did not (no fear). Carbon dioxide is a small, relatively inert, but highly volatile gas that not only gives beer its bubbles, but that also acts as one of the primary driving forces of anthropogenic climate change.

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Extrapolation of GPRD data indicates 6,574 drug misusing or dependent diagnosed patients in primary care in 1997 compared with 3,643 clients altace capsule reported by all agencies including general practitioners (GPs) to the RDMD. Palladium-catalyzed tandem cyclization of allenyl-aldehydes and -ketones with aryl iodides and Bu3SnSnBu3. Children with pulmonary hypertension routinely undergo pulmonary vascular resistance studies to assess the disease severity and vasodilator responsiveness. However, whether the resting-state networks (RSNs) are altered in adolescents with CD remains unknown. Significant correlation between uric acid levels and flow-mediated dilatation in patients with masked hypertension. However, there are no preoperative and intraoperative criteria which can successfully establish the possibilities for development of postoperative pulmonary edema.

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