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Calan

Calan is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels. Calan is used to treat hypertension (high blood pressure), angina (chest pain), and certain heart rhythm disorders.

Other names for this medication:
Calaptin, Covera, Isoptin, Vasopten, Veramil, Verapamil, Verelan, Verpitos, Zolvera

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Estrace, Decadron, Noroxin, Evista, Clarinex, Medrol, Symmetrel, Rocaltrol, Claritin

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Also known as: Verapamil

Description

Calan is in a group of drugs called calcium channel blockers. Calan is used to treat hypertension, angina and certain heart rhythm disorders. It works by relaxing the muscles of your heart and blood vessels. Calan is also known as Verapamil, Calaptin, Isoptin, Verelan, Bosoptin, Covera-HS.

Dosage

This section provides information on the proper use of a number of products that contain verapamil. It may not be specific to Calan. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium. Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet .

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well .

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease .

Swallow the extended-release tablet whole with a full glass of water. Do not break, crush, or chew it. It is best to take this medicine with food .

If you cannot swallow the verapamil extended-release capsules, you may open it and sprinkle the pellets contained in the capsule on one tablespoon of applesauce. This mixture must be swallowed immediately with a glass of cool water. The applesauce should not be hot and should be soft enough to be swallowed without chewing. Do not chew or crush the pellets .

If you are taking the extended-release tablets, you may sometimes notice what looks like a tablet in your stool. This is the empty tablet shell that is left after the medicine has been absorbed .

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For chest pain: For oral dosage form (tablets): Adults—The usual dose is 80 to 120 milligrams (mg) three times a day. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor . For oral dosage form (extended-release tablets, 24 hr): Adults—At first, 180 milligrams (mg) once daily at bedtime. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor . For heart rhythm problems: For oral dosage form (tablets): Adults—The total usual dose is 240 to 480 milligrams (mg) divided in three or four equal doses per day. Children—Use and dose must be determined by your doctor . For high blood pressure: For oral dosage form (tablets): Adults—At first, 80 milligrams (mg) three times a day. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor . For oral dosage form (extended-release capsules): Adults—At first, 200 milligrams (mg) once daily at bedtime. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor . For oral dosage form (extended-release tablets): Adults—At first, 180 milligrams (mg) once daily in the morning. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor . For oral dosage form (extended-release tablets, 24 hr): Adults—At first, 180 milligrams (mg) once daily at bedtime. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor .

Overdose

If you overdose Calan and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Calan overdosage: slow heartbeat, fainting fit.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Calan SR dosage information

Side effects

The most common side effects associated with Calan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies have not been performed on the relationship of age to the effects of verapamil in the pediatric population. Safety and efficacy have not been established .

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Each country needs to take into account the features of HIV and AIDS epidemiology that are peculiar to it, its infrastructure, and the resources that are available. Evidently, such an approach is critically essential in aquaculture, where interspecific hybridization is very common and usually detected by changes in ploidy levels only. The objective is to determine whether dexmedetomidine improves oxygenation and lung mechanics in patients with moderate COPD during lung cancer surgery. Resolution of encrusted cystitis has previously been achieved via surgical debridement of the bladder and treatment with antimicrobial drugs. New tacrine analogs as acetylcholinesterase inhibitors - theoretical study with chemometric analysis. Preoccupation, food, and failure: an investigation of cognitive performance deficits in dieters. This activates keratinocytes, endothelial cells and neutrophils. Collaboration and Conflict: Looking Back at the 30-Year History of the AIDS Clinical Trials Group. Structural white matter differences underlying heterogeneous learning abilities after TBI. Different chromatographic behaviours on blue sepharose CL-6B of free and estradiol complexed forms of the estrogen receptor from DMBA-induced rat mammary tumors.

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Recent observations that recombinant Sendai viruses (SeV) can infect a broad range of different tissues suggested SeV to be a good candidate for future gene therapeutic strategies in which dividing and non-dividing cells have to be reached. Serum rT3 concentration returned to reference range, then decreased significantly days 5 and 7 after stopping endotoxin treatment. Central corneal refractive power was measured using an autorefractor. It is currently unclear how the unusual properties of LGP2 mediate opposing roles. The neural correlate of working memory has been found in different brain areas that are involved in organizing perceptual or motor functions. Several intracellular proteins expressed in lymphocytes meet the criteria of membrane-associated adapter proteins such as members of the Dok family. Poor retention of glaucoma knowledge may impact the likelihood of patient follow-up, and reinforcement with repeated counseling may be beneficial with regard to both disease knowledge and follow-up. Atrial fibrillation after ondansetron for the prevention and treatment of postoperative nausea and vomiting: a case report. Nef Proteins from HIV-1 Elite Controllers Are Inefficient at Preventing Antibody-Dependent Cellular Cytotoxicity. The case of Serbia/Yugoslavia: an analysis through spiral dynamics.

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Therefore, sonography showing zones of decreased parenchymal echogenicity was complementary to radionuclide studies in the diagnosis of allograft rejection versus acute tubular necrosis. Neurogenic dural protein extravasation induced by meta-chlorophenylpiperazine (mCPP) involves nitric oxide and 5-HT2B receptor activation. This study evaluated the influence of different convergence angles and tooth preparation heights on the internal adaptation of Cerec crowns. The analytical assay is usable in the range of 10-500 ng ml(-1). A report of three medico-legal autopsy cases with special reference to distinctive histopathological alterations. It serves as an essential component required for the formation of hemolymph clots that seal wounds, and Idgf3 mutants display an extended developmental delay during wound healing. Compared to the placebo patients, those on estrogens had a significant increase in total REM sleep, a significant decrease in sleep latency. Two types of silica surface were investigated, one fully hydroxylated and the other partially dehydroxlated. Targeting heat shock protein 90 for the treatment of malignant pheochromocytoma. Fusion of the human gene for the polyubiquitination coeffector UEV1 with Kua, a newly identified gene.

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In conclusion, overeating SFAs promotes hepatic and visceral fat storage, whereas excess energy from PUFAs may instead promote lean tissue in healthy humans. Necrotizing fasciitis secondary to bevacizumab treatment for metastatic rectal adenocarcinoma. Polyphasic characterization of Aeromonas salmonicida isolates recovered from salmonid and non-salmonid fish. The same fungus produced sphaeropsidins A, B and C, sphaeropsidone and episphaeropsidone, which proved to be phytotoxic to cypress, and chlorosphaeropsidone and epichlorosphaeropsidone showing no phytotoxicity. The binding of peptides and proteins to lipid membrane surfaces is of fundamental importance for many membrane-mediated cellular processes. These data suggest that increased glucose in respiratory secretions in pathologic states, such as chronic rhinosinusitis or hyperglycemia, promotes tonic activation of T1R2/3 and suppresses T2R-mediated innate defense. MOs ionization induced by coulomb interaction were studied by measuring both ionization and partial dissociative cross sections through time of flight mass spectrometry and by obtaining the branching ratios for fragment formation via a model calculation based on the Born approximation.

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Using the nano- electrospray ionization (ESI)-LC-MS/MS detector, we identified 31 over-expressed proteins in WT mouse hypothalamus compared to the KO counterparts. Incidence and mortality of obstructive lung disease in rheumatoid arthritis: a population-based study. PRRSV nonstructural protein 2 (nsp2) is a multifunctional polypeptide with strain-dependent influences on pathogenicity. DNA was subsequently extracted from archived portions of liver, spleen, gizzard, heart, lung and kidney. Uptake and metabolism of hexamethylmelamine and pentamethylmelamine by L5178Y lymphoblasts in vitro.

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In both groups of cells, PKC-delta and -epsilon were mainly expressed at the nuclear level. Mice lacking functional CD95-ligand display reduced proliferation of the intestinal epithelium without gross homeostatic alterations. Enhancing cortical GABAergic transmission activity by brain infusion with diazepam not only caused a precocious onset of the high coincidence of binocular inputs and OD plasticity in pre-CP mice, but rescued both of them in dark-reared mice, suggesting a tight link between coincident binocular inputs and CP plasticity. Six patients had a weight gain of more than 3 kg during the MPA administration, compared with none during the placebo administration. We investigated the effect of treatment with danazol on the levels of CA-125, CA-19-9, CA 15-3, SIL-2R, IL-6, IL-1a, TNE-a, SCD8 and SCD4 in this woman. The patients were evaluated on the extent of resection, progression-free survival (PFS), and development of radiation-related toxicities.

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Demonstration of the direct vasodilatory action of yohimbic acid and Py-tetrahydroquinoline. However, the molecular architecture and the precise dynamic function of the centromere-kinetochore complex during mitosis remain poorly understood. The reactions between MQ and solvated electrons and superoxide anion were also studied. Retinal preconditioning and the induction of heat-shock protein 27. Several biochemical characteristics and functions of human blood platelets. This is an update of a Cochrane review first published in 2004, and previously updated in 2006. monocytogenes ATCC 15313 was nisin present at t0 followed by the LPS addition 4 h later, when the maximum inhibitory effect of nisin was reached. The loss of spindle assembly checkpoint occurred with a high frequency in HCC with CI. The goal of this article is not to push patients towards any particular route but to let them know of all the choices available.

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Electrostatics explains the shift in VDAC gating with salt activity gradient. This study compares the frequencies of plasminogen activator inhibitor-1 (-675) 4G/5G polymorphism and its relationship with eight antiphospholipid antibodies (aPLs) in serum of 157 patients with repeated pregnancy loss (RPL). Data from 11 population studies on depression in persons aged 65 and above were pooled, yielding a total of 15,890 respondents. An antiaromatic electrode-active material enabling high capacity and stable performance of rechargeable batteries. Microbial degradation of an organophosphate pesticide, malathion. To measure the validity and reliability of the PL-FSDS-R and to determine optimal cutoff values. The Xenopus oocyte is used as a convenient cell expression system to study the structure and function of heterogenic transmitter receptors and ion channels. Hyperkalemia, very severe complication of acute ischemia syndromes of the limbs. For immunohistochemistry: sections were stained with anti-IDH1R132H antibody.

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Our results suggest that VATS compared to other techniques for PDA closure is rapid, cost-effective, painless and more cosmetic. The outcome of interest is sustained virological response (SVR). The reduced immune response of obese patients to vaccination can be deleterious not only for the patient but also for the community. Calibrated Framingham function charts of overall CHD risk for the Spanish population are presented. Associations between HRQOL and adverse dialysis outcomes (ie, death and hospitalization) also were assessed for all patients and by ethnicity. Current problems on the microbiology in inflammatory diseases of the ears and upper respiratory tract. The purpose of this qualitative case study was to detail the life experiences associated with living with mobility, cognitive, and sensory loss experienced by a woman and her sister who participated in an ongoing ethnographic study of mobility impairment in women. Spinosad is an insect control agent that is derived from a naturally occurring soil bacterium and is effective on several classes of insects, especially Lepidopteran larvae.

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This preparation of rhodopsin-bearing post-Golgi carriers is a first step towards the proteomics of this important organelle. Reinforcement of the bronchial stump with TachoComb is a simple procedure, comparable to coverage with viable tissue, and should be considered in the prevention of postpneumonectomy BPF. Effects of WIN 55,212-2 (a non-selective cannabinoid CB1 and CB 2 receptor agonist) on the protective action of various classical antiepileptic drugs in the mouse 6 Hz psychomotor seizure model. Three-dimensional (3D) printed models of the human skull and parts of it are being increasingly used for surgical education and customized preoperative planning. The study group included 201 infants with birth weights of less than 1000 g. Surgical treatment of tegumental cicatricial retractions of the hand. Several experiments have been conducted on combustion of the synthetic fuel in the pilot-scale incinerator with varying fuel-air equivalence ratio. This method could be a simple, useful alternative for managing airsacculitis in nonhuman primates. The role of myosin phosphorylation in regulating smooth muscle contraction has been investigated by quantitating the myosin phosphate content of tracheal smooth muscle frozen during contraction or relaxation. The final velocity of the walls depends linearly on the distance from the bifurcation.

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In this review authors address colostrum proteins implications in different domestic ruminant species. The body-energy paradigm levaquin 500 mg oral dose assumes health and disease are functions of the flow and balances of life energies. Interpretation of intraoperative recurrent laryngeal nerve monitoring signals: The importance of a correct standardization. Anatomical studies of cerebellar fibre connections with special reference to problems of functional localization. Hydration and transepidermal water loss values between healthy elderly subjects and incontinent elderly subjects were significantly different on buttock skin. Blood samples (0.45-0.50 ml) were withdrawn without anesthesia every 20 min from 1400-2000 h through an atrial cannula implanted the same morning. Engineering of functional, perfusable 3D microvascular networks on a chip. Effects of isolated post-challenge hyperglycemia on mortality in American Indians: the Strong Heart Study.

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The NPY Y4 receptor has been identified recently as a potential mediator of the regulation of food intake. The current study investigated the effects of acute PF removal on spontaneous firing rates recorded from single neurons in the right inferior colliculus of guinea pigs with normal hearing (which did not receive acoustic trauma) or with hearing loss caused by acoustic trauma. In conventional animals, further reductions in complement levels could occur as a result of infection associated with malnutrition. Sorption of metals onto natural organic matter as a function of complexation and adsorbent-adsorbate contact mode. The severity of subcortical white matter lesions is related to the presence of depressive symptoms and to a history of late-onset depression. The 13CO2/12CO2 ratio was measured by using infra-red spectroscopy(IR) and gas chromatography/mass spectrometry(GC-MS). The upregulated levels of co-stimulators CD40/CD40L on B cells and T cells may play an important role in the immune pathogenesis of breast cancer.

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