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Bupropion is used in the treatment of depression and smoking addiction. This medicine helps by increasing the level of chemical messengers in the brain that relax the nerves and have a calming effect on the brain.

Other names for this medication:
Aplenzin, Budeprion, Bupdep, Bupraset, Bupron, Bupropion, Ession, Nicotex, Smoquit, Unidep, Zyban

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Intagra, Cleocin, Lioresal, Compazine, Aceon, Eriacta, Strattera, Silagra


{name} SR is an antidepressant used to treat major depressive disorder and seasonal affective disorder. The Zyban brand of bupropion is used to help people stop smoking by reducing cravings and other withdrawal effects.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Too much of this medicine can increase your risk of a seizure.

You may take Bupropion SR with or without food.

Swallow the extended-release tablet whole and do not crush, chew, or break it.

You should not change your dose or stop using Bupropion SR suddenly, unless you have a seizure while taking this medicine. Stopping suddenly can cause unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

If you take Zyban to help you stop smoking, you may continue to smoke for about 1 week after you start the medicine. Set a date to quit smoking during the first 2 weeks of treatment. Talk to your doctor if you have trouble quitting after taking Zyban for 7 to 12 weeks.

Your doctor may prescribe a nicotine replacement product (such as patches or gum) to help you stop smoking. Start using the nicotine replacement product on the same day you stop (quit) smoking or using tobacco products.

Some people taking Bupropion SR (Bupropion or Zyban) have had high blood pressure that is severe, especially when also using a nicotine replacement product (patch or gum). Your blood pressure may need to be checked before and during treatment with this medicine.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

You may have nicotine withdrawal symptoms when you stop smoking, including: increased appetite, weight gain, trouble sleeping, trouble concentrating, slower heart rate, having the urge to smoke, and feeling anxious, restless, depressed, angry, frustrated, or irritated. These symptoms may occur with or without using medication such as Zyban.

Smoking cessation may also cause new or worsening mental health problems, such as depression.

This medicine may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use Bupropion SR.

Store at room temperature away from moisture, heat, and light.

Detailed Bupropion SR dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Bupropion SR can be fatal. Overdose symptoms may include muscle stiffness, hallucinations, fast or uneven heartbeat, shallow breathing, or fainting.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bupropion are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Drinking alcohol with bupropion may increase your risk of seizures. If you drink alcohol regularly, talk with your doctor before changing the amount you drink. Bupropion can also cause seizures in people who drink a lot of alcohol and then suddenly quit drinking when they start using the medication.

Bupropion may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

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Early termination of a trial of mycophenolate mofetil for treatment of interstitial cystitis/painful bladder syndrome: lessons learned. Present findings show by the first time that the aqueous crude extract of Senecio cardiophyllus possesses the ability to increase the ejaculatory capacity in male rats. From microsurgery to supermicrosurgery: Experimental feasibility study and perspectives. Ganglion cyst of the distal forearm mimicking a malignant tumour--a case report. A 50-year-old female without a history of liver disease developed cholestatic hepatitis during her second week of fenofibrate treatment. NSAIDs especially the cox-2 inhibitors should be avoided following fractures or implant surgery. Vaccination strategies for the prevention of herpes zoster and postherpetic neuralgia.

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LY294002, dominant-negative (DN) phosphatidylinositol 3-kinase (PI3K), or AKT(DN) inhibited NFkappaB activation, p65 transactivation, and cyclooxygenase-2 (COX-2) expression induced bactrim cellulitis dosing by lauric acid or constitutively active (CA) TLR4. State and the perspectives of the development of the emergency medical services in the Leningrad district. In this work we establish a framework for finding recurrent cis-regulatory modules in the promoters of a selected set of genes and scoring their statistical significance. Data also exist on which to assess risks for winchite (sodic tremolite) and anthophyllite asbestos. For the data set we analyzed, the use of FA/PR to integrate multiple chemical species into source-related PM exposure metrics was found to be a more sensitive tool than the traditional approach using PM mass alone. The proposed technique is based on what we believe to be a novel balanced all-optical ultrafast differentiation scheme, and it enables a real-time conversion of the instantaneous frequency variation of an arbitrary complex (amplitude and phase) optical signal into a temporal intensity profile while simultaneously providing an efficient cancellation of the intensity noise. Commentary: ethics-related implications and neurobiological correlates of false confessions in juveniles.

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