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Buconif (Nifedipine)

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Buconif is used to treat hypertension (high blood pressure) and angina (chest pain). Buconif is in a class of drugs called calcium channel blockers. Buconif relaxes (widens) your blood vessels (veins and arteries), which makes it easier for the heart to pump and reduces its workload.

Other names for this medication:
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Differin, Zanaflex, Rocaltrol, Geodon, Retin, Zyloprim

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Buconif PA 20. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Buconif and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Buconif dosage information

Side effects

The most common side effects associated with Buconif are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Praevia tumors of exceptional etiology: pelvic meningocele with anterior sacral spina bifida. Hydronephrosis is an important early indicator of colorectal cancer recurrence, even in the absence of a mass. These results suggest that there could be a specific gateway molecule to induce G-CSF in macrophages. In vivo study was conducted in advance using zebrafish fed with a normal diet and a cholesterol-enriched diet. Preparation and characterization of amine-functionalized sugarcane bagasse for CO2 capture. Epigenetic mechanisms in the development and maintenance of dopaminergic neurons. Many human gastrointestinal facultative anaerobic and aerobic bacteria possess alcohol dehydrogenase (ADH) activity and are therefore capable of oxidizing ethanol to acetaldehyde. Open and closed loop insulin delivery systems in diabetes: current status. Soluble major histocompatibility complex class I-related chain B molecules are increased and correlate with clinical outcomes during rhinovirus infection in healthy subjects.

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Studies on therapeutic effects and side effects in models of chronic inflammation are now necessary to establish pharmacodynamics of dexa-AbEsel and/or AbEsel-immunoliposomes in the treatment of chronic inflammation. The null mutants of ADH6 or ADH7 genes were hypersensitive to vanillin and reduced vanillin less efficiently than the wild type, confirming the importance of Adh6 and Adh7 in vanillin detoxification. Effectiveness of Chin-tuck Maneuver to Facilitate Swallowing in Neurologic Dysphagia. The pathophysiologic relationship between LPG and TMA should be investigated further. A method for calculating the potency of antibiotics from the two-dose plate assay technique.

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Successful treatment by defibrination with ancrod in a patient with hyperacute renal allograft failure and a deficiency of plasma prostacyclin stimulating factor. The relation of the Ca/P ratio to bone quality remains under investigation. Capsules containing L-arginine (700 mg) or placebo were administered four times daily during a period of TD-GTN therapy. Application of stationary wavelet transformation to winter wheat SPAD hyperspectral monitoring. Polymorphisms in the Toll-Like Receptor and the IL-23/IL-17 Pathways Were Associated with Susceptibility to Inflammatory Bowel Disease in a Danish Cohort. Yet while the physiological pH may provide an optimum environment for LKR activity, the pH optima for the activities of both the linked and non-linked SDH enzymes were above pH 9, suggesting that these two enzymes may operate under suboptimal conditions in vivo. Unscheduled DNA synthesis induced by 4-nitroquinoline-1-oxide in xeroderma pigmentosum cells and their complementing heterodikaryons. Study of the phagocytic and metabolic function of the reticulo-endothelial system, with the aid of an iodine 131-labeled protein complex.

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Purification and characterization of the major allergen from Dermatophagoides pteronyssinus-antigen P1. Long-term effects of non-supervised home exercise therapy on quality of life in patients with myocardial infarction. Activated protein C (APC) exhibits anticoagulant and antiinflammatory properties. Acquired equine polyneuropathy is a potentially fatal neurological disease characterised by pelvic limb knuckling. However, the role of UL16 during the course of HCMV infection remained unclear. Quality comparison of electronic versus paper death certificates in France, 2010.

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Molecular dynamics and ligand exchange in magnesium complexes: evidence for both dissociative and associative ligand exchange. Riverine barriers and the geographic distribution of Amazonian species. Incidences of non-symptomatic SLD detected by SL gap view in normal wrists increased by age. More severely affected embryos skipped meiosis II altogether and exhibited striking defects in meiotic exit. Histamine Recycling Is Mediated by CarT, a Carcinine Transporter in Drosophila Photoreceptors. Consequently, available water quality datasets span only relatively short time scales unlike water quantity data. Reading more than 100 fields per smear or examining a third sputum has insufficient marginal returns to justify the workload. The glass transitions were experimentally identified as near discontinuities in the thermal expansion. The present study examined the effects of cyanidin-3-glucoside (C3G), a type of anthocyanin abundant in dark-skinned berries, on glyLDL-induced ROS production, NOX activation and mETC enzyme activity in porcine aortic EC (PAEC).

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Enzymes of carbohydrate metabolism of mycelial fungi from marine environments. Ensemble of membrane and cytoskeleton remodelings in cell migration. Clonidine (30 micrograms/kg, i.v.) caused a significant decrease in salivation (P less than 0.05) for the first 50 min after injection. Many in this population will be at risk for opportunistic infections, which are familiar to doctors who have treated people infected with human immunodeficiency virus (HIV). Radiographic measures of settlement phenomenon in patients with medial compartment knee osteoarthritis. Are obesity and other physical comorbidities related to mental illness?. Ovarian wedge resection by minilaparotomy might be an alternative treatment approach in patients with PCOS who did not conceive with standard ovulation induction protocols. Although some design modifications are necessary to reduce current complications, the polyurethane-covered retrievable nitinol stent seems feasible for use in the urethra. This result could be explained by the increase in mRNA expression of glucose transporters-1 and -2 and glucokinase, as determined by quantitative real-time reverse transcriptase-polymerase chain reaction.

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To assess the time lag between the diagnosis of human immunodeficiency virus (HIV) and the initiation of antiretroviral therapy (ART) in pregnant women. However, the roughened surfaces showed this significant enhancement in calcium content only with 1000 ng/ml BMP-2. After screening of titles and abstracts, full papers of 10 studies were obtained and assessed for eligibility. Our aim was to compare the radiation exposure, by taking fluoroscopy time (FT) as a surrogate of radiation exposure, to the operator with femoral and radial routes. The progeny of these transiently catecholaminergic (TC) cells have not been fully characterized. Reflections on the possible incorporation of avizafone in three-drug emergency treatment are presented. The GSI in female theophylline er dosing carps from the contaminated site was smaller than that recorded at the reference site.

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Histological characterization of dilated cardiomyopathy in the juvenile toy Manchester terrier. The importance of the aflatoxins from food safety and economic standpoints has continued to drive the development of new analytical methods for these mycotoxins. To assess the relationship between beverage choices and the adequacy of nutrient intakes among children and adolescents. The primary aim of this study was to prospectively identify factors predictive of survival in patients referred for PEG placement. Many cases are inherited, either as an X-linked, autosomal dominant or autosomal recessive trait. It is tempting to speculate that CAD plays a tumour-suppressive role in hepatocarcinogenesis. This study analyzed 50 oral and maxillofacial NHL cases and 10 reactive lymph nodes (formalin fixed and paraffin embedded) by flowcytometry (FCM).

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Single-particle motion in three-dimensional vibrofluidized granular beds. This N-terminal domain is dispensable for its neurogenic function, indicating that Ascl1 acts by different mechanisms at different times. Together these data indicate that antibodies assembled from V(H) gene segments DP-5 and the closely related germline gene segments DP-10, DP-14, and DP-88 target 2 distinct antigenic sites in the C2 domain of factor VIII. The authors recommend use of national immigration data to objectively identify countries of birth with high proportions of humanitarian entrants, matched by time period to the study dataset. The study also discusses several antidiarrheal opioid agonists, as well as opioids and opioid mimetics encompassing the concept of ligand-biased agonism and truncated opioid receptor splice variants. We present the first three-dimensional images that show the tooth whorl occupying the entire mandibular arch, and which is supported along the midline of the lower jaw. Degradation products and a unique endonuclease in heterogeneous nuclear RNA in sea urchin embryos. Core needle biopsy results were compared with surgical biopsy in 265 cases. To determine what factors can predict conversion to sinus rhythm, we retrospectively studied 201 consecutive patients who received ibutilide for treatment of atrial fibrillation or flutter. A role for glycosaminoglycans in the development of collagen fibrils.

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Effect of different operating parameters such as initial concentration, temperature and pH on the extent of degradation using acoustic cavitation has been investigated. Antidepressant drugs of the selective serotonin reuptake inhibitor (SSRI) or serotonin-norepinephrine reuptake inhibitor (SNRI) families are the first line of therapy in depressive disorders, and failure to achieve complete symptom remission after a trial of an SSRI or SNRI at optimal doses should be followed by a second trial with a drug from the other antidepressant family. The impact of wild-type reversion on transmitted resistance surveillance. The aim of our study was to establish normative data in a sufficiently large group of healthy subjects, using a rigorously standardized examination technique. During the planning and carrying out of clinical trials on potential psychotropic agents various difficulties arise when applying experimental-psychological procedures, especially on self- and non-self-rated behaviour. Quantitative standardized assessments of upper extremity function were obtained using the fine motor skills section of the Peabody Developmental Motor Scales (PDMS) test. Identification of a T cell hybridoma which produces extraordinary quantities of macrophage activating factor.

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To compare the risk of secondary cancer from scattered and leakage doses following intensity-modulated radiotherapy (IMRT), volumetric arc therapy (VMAT) and tomotherapy (TOMO) in patients with lung cancer. Rapid determination of gemifloxacin in human plasma by high-performance liquid chromatography-tandem mass spectrometry. Some calculations of the non-uniformity factor in the induction of bone cancer by internal emitters. Malignant esophagogastric junction obstruction: efficacy of balloon dilation combined with chemotherapy and/or radiation therapy. Effect of thyroid stimulating hormone, thyroxine, diiodotyrosine, 2,4-dinitrophenol and these related compounds on the thiamine metabolism. We have demonstrated previously that zinc overload neurotoxicity involves protein kinase C (PKC)-dependent rises in intracellular levels of reactive oxygen species (ROS). Probing interactions between the U2 small nuclear ribonucleoprotein and the DEAD-box protein, Prp5.

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Cancer knowledge among Spanish women participating in literacy schemes. This review of contemporary techniques, devices, and results suggests that transcatheter occlusion of surgical shunts is effective and safe. Based on the data presented, cytokine patterns in the AH do not appear to distinguish corneal opacification due to graft rejection from that due to herpes keratitis. Defective death evista tab 60 mg receptor signaling as a cause of tumor immune escape. Surgical repair of the mitral valve is being increasingly performed to treat severe mitral regurgitation. The animals were bedded on either untreated sawdust or sawdust that had been treated with a hydrated lime-based conditioner. In Spring 1997, the California Department of Health Services (CDHS) launched a statewide culturally sensitive and ethnically specific media campaign directed toward African Americans.

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