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Bactiver (Trimethoprim)

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Bactiver is a combination of two synthetic (man-made) antibiotics, sulfamethoxazole and trimethoprim. Both drugs reduce the ability of some bacteria to utilize folic acid for growing. Sulfamethoxazole is an anti-bacterial sulfonamide, a sulfa drug.

Other names for this medication:
Avlotrin, Bactricida, Bascul, Betam, Biseptol, Biseptrin, Bismoral, Ciplin, Cozole, Dosulfin, Dotrim, Ectaprim, Eusaprim, Groseptol, Infectrin, Kaftrim, Momentol, Oribact, Primadex, Sanprima, Sigaprim, Triforam, Trimoks, Trimol, Trimosul, Vanasulf, Zaxol, Zoltrim

Similar Products:
Avapro, Tenormin, Ceclor, Sumycin, Indocin, Mircette, Loxitane

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Also known as: Trimethoprim


This medication is used to treat a wide variety of bacterial infections. It is also used to treat a certain type of pneumonia (pneumocystis pneumonia) in patients with a weakened immune system. This medication is a combination of 2 antibiotics: sulfamethoxazole and trimethoprim. It works by stopping the growth of bacteria and the pneumocystis fungus.


This section provides information on the proper use of a number of products that contain sulfamethoxazole and trimethoprim. It may not be specific to Bactiver DS. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

Sulfamethoxazole and trimethoprim combination is best taken with a full glass (8 ounces) of water. Several additional glasses of water should be taken every day, unless otherwise directed by your doctor. Drinking extra water will help to prevent some unwanted effects (eg, crystals in the urine). .

For patients taking the oral liquid, use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop taking this medicine too soon, your symptoms may return.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (liquid or tablets): For treatment of bacterial infections: Adults—1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 10 to 14 days. Your doctor may adjust this dose if needed. Children 2 months of age and older—Dose is based on body weight and must be determined by your doctor. The usual dose is 40 milligrams (mg) per kilogram of body weight of sulfamethoxazole and 8 milligrams (mg) per kilogram of body weight of trimethoprim, given in two divided doses every 12 hours for 10 days. Weighing 40 kilograms (kg)—4 teaspoonfuls (20 mL) of oral liquid or 2 tablets (or 1 DS tablet) 2 times a day for 10 days. Weighing 30 kg—3 teaspoonfuls (15 mL) of oral liquid or 1 ½ tablet 2 times a day for 10 days. Weighing 20 kg—2 teaspoonfuls (10 mL) of oral liquid or 1 tablet 2 times a day for 10 days. Weighing 10 kg—1 teaspoonful (5 mL) of oral liquid 2 times a day for 10 days. Children younger than 2 months of age—Use is not recommended. For treatment of bronchitis: Adults—1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 14 days. Children 2 months of age and older—Use and dose must be determined by your doctor. Children younger than 2 months of age—Use is not recommended. For treatment of Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP): Adults and children 2 months of age and older—Dose is based on body weight and must be determined by your doctor. The usual dose is 75 to 100 milligrams (mg) per kilogram of body weight of sulfamethoxazole and 15 to 20 milligrams (mg) per kilogram of body weight of trimethoprim each day, given in equally divided doses every 6 hours for 14 to 21 days. Weighing 80 kilograms (kg)—10 teaspoonfuls (50 milliliters (mL)) or 5 tablets (or 2 ½ DS tablets) 4 times a day for 14 to 21 days. Weighing 64 kg—8 teaspoonfuls (40 mL) or 4 tablets (or 2 DS tablets) 4 times a day for 14 to 21 days. Weighing 48 kg—6 teaspoonfuls (30 mL) or 3 tablets (or 1 ½ DS tablets) 4 times a day for 14 to 21 days. Weighing 40 kg—5 teaspoonfuls (25 mL) or 2 ½ tablets 4 times a day for 14 to 21 days. Weighing 32 kg—4 teaspoonfuls (20 mL) or 2 tablets (or 1 DS tablet) 4 times a day for 14 to 21 days. Weighing 24 kg—3 teaspoonfuls (15 mL) or 1 ½ tablets 4 times a day for 14 to 21 days. Weighing 16 kg—2 teaspoonfuls (10 mL) or 1 tablet 4 times a day for 14 to 21 days. Weighing 8 kg—1 teaspoonful (5 mL) 4 times a day for 14 to 21 days. Children younger than 2 months of age—Use is not recommended. For prevention of Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP): Adults—800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim once a day. Children 2 months of age and older—Dose is based on body size and must be determined by your doctor. The usual dose is 750 mg of sulfamethoxazole and 150 mg of trimethoprim per square meter (m[2]) of body surface each day. This is given in equally divided doses two times a day for 3 days a week on consecutive days (eg, Monday, Tuesday, Wednesday). However, the dose is usually not more than 1600 mg of sulfamethoxazole and 320 mg of trimethoprim per day. Children younger than 2 months of age—Use is not recommended. For treatment of traveler's diarrhea: Adults—1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 5 days. Children 2 months of age and older—Use and dose must be determined by your doctor. Children younger than 2 months of age—Use is not recommended.


If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe nausea/vomiting/diarrhea, severe dizziness or drowsiness, mental/mood changes.


Consult the product instructions and your pharmacist for storage details. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Before taking sulfamethoxazole with trimethoprim, tell your doctor or pharmacist if you are allergic to sulfa medications or trimethoprim; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, certain blood disorders (such as porphyria, anemia due to folate vitamin deficiency), history of blood disorders caused by trimethoprim or sulfa medications, vitamin deficiency (folate or folic acid), severe allergies, asthma, decreased bone marrow function (bone marrow suppression), a certain metabolic disorder (G6PD deficiency), underactive thyroid, mineral imbalances (such as high level of potassium or low level of sodium in the blood). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths or sunlamps. Use a sunscreen and wear protective clothing when outdoors. If you have diabetes, this product may affect your blood sugar levels. Check your blood sugar levels regularly as directed by your doctor. Tell your doctor immediately if you have symptoms of low blood sugar (see Side Effects section). Your doctor may need to adjust your diabetes medication, exercise program, or diet. Older adults may be more sensitive to the side effects of this drug, especially skin reactions, blood disorders, easy bleeding/bruising, and a high potassium blood level. Patients with AIDS may be more sensitive to the side effects of this drug, especially skin reactions, fever, and blood disorders. This medication is not recommended for use during pregnancy especially near the expected delivery date because of possible harm to the unborn baby. Consult your doctor for more details. This drug passes into breast milk. While there have been no reports of harm to healthy infants, this drug may have undesirable effects on infants who are ill or premature or have certain disorders (jaundice, high blood levels of bilirubin, G6PD deficiency). Therefore, breast-feeding is not recommended for infants with these conditions. Consult your doctor before breast-feeding.

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Hypotaurine, N-methyltaurine, taurine, and glycine betaine as dominant osmolytes of vestimentiferan tubeworms from hydrothermal vents and cold seeps. This paper is devoted to the ideas and purposes of universalistic medicine as a knowledge of restoring, preserving and improving health state and making possible to evaluate individual human being as an integrated subject of creative evolution. Active acromegaly is associated with lowered mean serum TC and LDL. These findings imply that the proteolytic machinery present in the cytoplasmic compartment is sufficient to degrade the AHR and that nuclear translocation, binding with ARNT, or DNA binding are not necessary for efficient degradation of the AHR. One hundred thirty-nine consecutive in-house surgical cases of pT3 CRC between 1993 and 2011 were examined. The ketogenic diet, originally introduced in the 1920s, has been undergoing a recent resurgence as an adjunctive treatment for refractory epilepsy, particularly in children. More research is needed to better understand the underlying pathophysiological processes leading to eosinophilic gastrointestinal infiltration in patients with CTD. In E2-treated mice, puerarin and TIP obviously inhibited the growth of vigina induced by E2. Small-angle scattering gives direct structural information about a membrane protein inside a lipid environment. A randomized trial comparing tamoxifen alone versus tamoxifen plus CMF.

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Electrophoretic analysis revealed that the enzyme was of mouse, not chick, origin. In the current study, we compared the relative expression of these five CYP4 genes and their associated levels of protein expression among field-collected and laboratory susceptible populations. Insulin-like growth factors (IGFs) are closely related to hepatocellular glucophage xr 1000 mg price in malaysia carcinoma growth. Some of the technical difficulties can be addressed by the use of intraoperative fluoroscopy which may improve the accuracy of acetabular component placement. The technique has subsequently been introduced into paediatric rheumatology practice, although much of the evidence supporting its use remains anecdotal or based on open, non-controlled studies. Effectiveness of donepezil at six months in the treatment of cognition deterioration in patients with Alzheimer-type dementia. The direct observation of temperature-dependent lipid phase equilibria, using two-photon excitation fluorescence microscopy on giant unilamellar vesicles (GUVs) composed of different lipid mixtures, provides novel information about the physical characteristics of lipid domain coexistence.

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Vascularized free flaps for reconstruction after resection of congenital arteriovenous malformations of the hand. It is shown that IGF-I significantly induces the expression of osteoclasts and osteoblasts and the subsequent bone remodelling, and that the effect may be additive as compared to that of mechanical masticatory loading, which seems to be more important in bone remodelling in terms of the numbers of osteoclasts and osteoblasts. A two-month-old female Tibetan terrier was re-presented with an incomplete closure of the patent ductus arteriosus. The fibritin construct was more stable to heat and reducing conditions than the GCN4 construct. In addition, it suggests that serum hepcidin may discriminate microcytic inflammatory anemia of Juvenile Idiopathic Arthritis from iron deficiency anemia. Adequate contraception is an essential component of managing pulmonary hypertension in women of childbearing age. The psychosocial outcome of adolescent-onset schizophrenia: a 12-year followup. Food restriction inhibits the growth of intestinal polyps in multiple intestinal neoplasia mouse. Similar lipid emulsion-Rift Valley fever studies in rhesus monkeys resulted in 37- and 300-fold increases in primary and secondary titers, respectively, compared with monkeys given vaccine alone.

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The effect of quinalbarbitone on the cerebral response to flicker in man. We report here the results of the endocrine studies and the morphological findings of the gonads in two male pseudohermaphrodite siblings with 5 alpha-reductase deficiency. Dietary sodium and target organ damage in essential hypertension. To compare the prognostic value of the danocrine pneumonia severity index and the severity score for community-acquired pneumonia (CURB-65) in predicting mortality and the need for ICU admission of patients with community-acquired pneumonia referred to our emergency department. We therefore reviewed the literature in the light of our own experience in neuroendoscopy since 1996.

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Computational Study of Phosphate Vibrations as Reporters of DNA Hydration. Economy class syndrome and other lessons from postmodern society. Correlation between radiology resident rotation performance and examination scores. We also performed cell therapy using MUC1 peptide-pulsed dendritic cells (MUC1-DCs) and MUC1-CTLs. With regard to Stat-1, densitometry showed 3.3- and 1.3-fold increases respectively in treated groups 1 and 2. Differential effects of intra-accumbal orexin-1 and -2 receptor antagonists on the expression and extinction of morphine-induced conditioned place preference in rats. One of the major issues is obtaining a secure and prolonged attachment of a deep-penetration Laser Doppler probe to the animal skull. Correlation between matrix metalloproteinase-9 periactin pediatric dose and endometriosis. MSUs were submitted for bacterial colony counts and resistance testing of isolates present in adequate numbers. Members of the transforming growth factor (TGF) beta family play critical roles in regulating placental functions.

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We show that with simultaneous registration and reconstruction of dual-axis tilt series, tomograms with higher resolution are obtained than by merging separately computed tomograms. These P2Y12 inhibitors might be superior to clopidogrel for reducing ischemic events in patients with coronary artery disease (CAD). In this paper, a novel graded band gap cubic-MgZnO-based solar-blind photodetector is successfully fabricated from Graded-Band-Gap-Cubic-MgZnO/i-MgO/p-Si heterojunction, via changing stoichiometry spatial gradient. Trans-femoral mechanical aspiration thrombectomy and angioplasty of the subclavian, brachial, ulnar and radial arteries was subsequently performed with successful recanalization. Effects of water content on the tetrahedral intermediate of chymotrypsin - trifluoromethylketone in polar and non-polar media: observations from molecular claritin vs allegra reviews dynamics simulation. Integrating electrophysiology and neuroimaging in the study of brain function. Abnormal epigenetic events have been reported in human pathologies but weakly documented in eye diseases. Data were collected retrospectively between January 1998 and January 2012. In a new approach to the characterization and quantification of metallothionein isoforms an on-line isotope-dilution method in combination with the coupling of capillary electrophoresis (CE) to an inductively coupled plasma-sector field mass spectrometer (ICP-SFMS) is reported.

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The UV-vis absorption, steady state/time resolved fluorescence spectroscopy and synchronous fluorescence, circular dichroism (CD) spectroscopy are used to investigate the interaction mechanisms of dihydroartemisinin (DHA) and 9-hydroxy-dihydroartemisinin (9-OH DHA), respectively. To determine the perception and attitudes of a rural community regarding the etiology, prevention, and treatment of blindness in adults. This paper describes the roentgen-morphologic aspects of enlarged lymph nodes in the mediastinal compartments as far as they can be detected with conventional studies. Distribution of drug-sensitivity of Staphylococcus aureus and E. The evolution and functions of the national board of examiners for osteopathic physicians and surgeons. Polysensitisation to multiple allergens occurs frequently in children with allergic rhinitis in general practice. Here, we have examined the potential role of vimentin in this wound healing. the degree of reproducibility of the PCR diagnosis should be taken into account in the interpretation of HPV data in clinical and epidemiological studies. The primary outcome was the renal survival rate and risk factors at renal biopsy.

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They share, after all, a similar manner of controlling microscope data input and analyzing the images the microscope provides. In this study the effect of oxytocin, PGF(2alpha), and PGE(2) on Humour immunodeficiency virus-1 production in acutely and persistently infected cells was measured. Application of the nitrocellulose transfer technique and alkaline phosphatase conjugated anti-immunoglobulin for determination of the specificity of monoclonal antibodies to protein mixtures. Peripheral retinal neovascularization and sarcoidosis: two case reports. It is conceivable that the downregulation of major histocompatibility complex class II molecules on LC in both the early and late skin manifestations of Lyme borreliosis is indicative of a poorly effective anti-B. Catheters were placed intraoperatively in 2 patients and percutaneously implanted in 3 patients with image-guided techniques. Rates of HIV, syphilis, and HCV infections among different demographic groups of female sex workers in Guangxi China: evidence from 2010 national sentinel surveillance data. Larger males were preferred by females and became socially dominant in agonistic interactions. The independent effect of the microbiota on fat accumulation has been demonstrated in mice, where transplantation of microbiota from obese mice or mice fed western diets to lean or germ-free mice produced fat accumulation among recipients. In addition, the prospects of HE4 detection for therapy-monitoring were evaluated in EOC patients.

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