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Azitrovid (Azithromycin)
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Azitrovid

Azitrovid is used to treat certain bacterial infections, such as bronchitis; pneumonia; sexually transmitted diseases (STD); and infections of the ears, lungs, sinuses, skin, throat, and reproductive organs.

Other names for this medication:
Altezym, Amsati, Atizor, Azatril, Azenil, Azicid, Azigram, Aziphar, Azithrocine, Azithromycin, Azithrox, Azitral, Azitro, Azitrobac, Azitrocin, Azitrom, Azitrovid, Azitrox, Azomac, Azromax, Azycyna, Azyter, Azyth, Bactexina, Binozyt, Ericiclina, Koptin, Kromicin, Macromax, Naxocina, Neblic, Novozitron, Oranex, Orobiotic, Pretir, Ribotrex, Simpli, Sumamed, Texis, Triamid, Tromic, Vinzam, Zetamax, Zitrolid, Zitroneo

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Also known as: Azithromycin

Description

Azitrovid (Azitrovid tablets and Azitrovid for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Azitrovid has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Azitrovid is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.

Azitrovid, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.

Azitrovid is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.

Azitrovid for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.

Dosage

You should take Azitrovid orally with a full glass of water 1 hour before or 2 hours after food. Take Azitrovid at the same time every day. Azitrovid treats different types of bacterial infections and can be used both by adults and by children. For children: The dosage is dependent upon the child's weight. In treatment of otitis media, take Azitrovid for 1-5 days. For adults: To treat pneumonia or throat/tonsil infection, the recommended dose is two 250 mg tablets on the first day and then one 250 mg tablet once a day for 4 more days. For the prevention of MAC (mycobacterium avium complex), the recommended dosage of Azitrovid is 1,200 mg per week. For the treatment of skin or infections, the recommended dosage is two 250 mg tablets on the first day and one 250 mg tablet for another 4 days.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not refrigerate or freeze the Zmax® extended-release oral suspension. After water has been added to the powder, use the dose within 12 hours and throw away any unused liquid after your dose.

You may store the Azitrovid® oral liquid at room temperature or in the refrigerator. Do not freeze the bottle. Do not keep the oral liquid for more than 10 days. Throw away any unused liquid after all doses are completed.

Detailed Azitrovid dosage information

Side effects

The most common side effects associated with Azitrovid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take antacids that contain aluminum or magnesium within 2 hours of taking Azitrovid.

Before taking Azitrovid, tell your doctor if you are using any of the following drugs: nelfinavir (Viracept); digoxin (Lanoxin, Lanoxicaps); ergot medicine such as methysergide (Sansert), ergotamine (Ergostat, Medihaler, Cafergot, Ercaf, Wigraine), dihydroergotamine mesylate (D.H.E., Migranal Nasal Spray); triazolam (Halcion); carbamazepine (Carbatrol, Tegretol); cyclosporine (Neoral, Sandimmune); phenytoin (Dilantin); cholesterol-lowering medicines such as lovastatin (Mevacor), atorvastatin (Lipitor), or cerivastatin (Baycol); a calcium channel blocker such as diltiazem (Cartia XT, Diltiazem, Tiazac), felodipine (Plendil), nicardipine (Cardene), nifedipine (Procardia, Adalat), nimodipine (Nimotop), verapamil (Calan, Covera-HS); HIV medicines such as indinavir (Crixivan), ritonavir (Norvir), saquinavir (Invirase); alprazolam (Xanax), diazepam (Valium), midazolam (Versed), triazolam (Halcion); theophylline (Theo-Dur, Theolair, Theochron); warfarin (Coumadin); pimozide (Orap); or another antibiotic, especially clarithromycin (Biaxin) or erythromycin (E-Mycin, E.E.S, Ery-Tab).

If you are using any of these drugs, you may not be able to use Azitrovid, or you may need dosage adjustments or special tests during treatment.

There are many other medicines that can interact with Azitrovid. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors.

Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

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Epileptic seizures can be induced by a variety of underlying diseases. Members of the cystatin superfamily are involved in an inherited form of cerebral amyloid angiopathy and readily form amyloid fibrils in vitro. The large subunit rRNA gene harboured the first group-IIB1 intron containing a putative active reverse transcriptase (RT) in mitochondrial genomes of fungi. Furthermore, we define properties an ITS should have in order to meet the identified requirements and differentiate them from evidence synthesis. It is likely that these changes are localized to the distal tubule and are especially marked in the collecting ducts although there is no direct evidence bearing on this. In this debate, we explore the dilemmas between the law, the ethical issues, the good clinical practice, and the wishes of the family. X-ray, ultrasound, and MRI of the head are reserved for a few indications. Macromolecules can be transported into the cells by endocytosis, either by can you mix childrens zyrtec with cough medicine phagocytosis or by pinocytosis.

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To evaluate the effect of topical interferon alpha-2b therapy in the treatment of melanocytic conjunctival lesions. Isolation and functional expression of pituitary peptidylglycine alpha-amidating enzyme mRNA. Catalytic generation of alpha,beta-unsaturated acyl imidazolium cations and enolates has been achieved, and their involvement in a Michael addition acylation sequence exploited, to provide a range of dihydropyranones. The study included 33 men with TBI who had been discharged from inpatient rehabilitation within 5 years. Preterm delivery was defined as delivery phenergan suppository storage before 37 wk gestation. NK cell expansion and enhanced cellular cytotoxicity against a B-cell lymphoma target were observed but did not correlate with response. Bone morphogenetic protein-2 induces differentiation of multipotent C3H10T1/2 cells into osteoblasts, chondrocytes, and adipocytes in vivo and in vitro. Tension controlled ligament balanced total knee arthroplasty: 5-year results of a soft tissue orientated surgical technique. Community treatment orders: an essential therapeutic tool in the face of continuing deinstitutionalization. Furthermore, most patient series combine adult and pediatric patients or high- and low-grade tumors, resulting in controversial data regarding optimal treatment of these children.

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Immunopotentiation has been demonstrated when Klebsiella O3 lipopolysaccharide (KO3 LPS), which possesses a linear mannan as the O-specific side chain, was injected subcutaneously into endotoxin plavix clopidogrel 75 mg side effects resistant C3H/HeJ mice together with soluble protein antigens. Point mutations that made the N terminus less hydrophobic had little effect on secretion of FGF-16, whereas making the central hydrophobic region less hydrophobic abolished secretion. Change in volumes relative to the point at which subjects progressed to a clinical diagnosis of AD (the index date) was modeled in aMCI-P. Isochromosome 1q in childhood Burkitt lymphoma: the first reported case in Korea. The 71 positives correlated in every instance with parallel Grocott methenamine silver-stained transbronchial biopsies or brushings. The thrombocytopenic effect is altogether less pronounced than the leukocytopenic effect. The fungus may spread to invade the palate, sphenoid sinus, cavernous sinus, orbits or cranially to invade the brain.

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Vacuole formation is associated with cytoplasmic destruction of the pancreatic cells. The operation was performed successfully for over the course of 3 hours 30 minutes. Since 2005, a Chikungunya fever outbreak of unprecedented magnitude occurred on several Indian Ocean islands. Birth weight is associated with type 2 diabetes mellitus and other late-onset metabolic diseases. We observed axial banding patterns with periods ranging from 20 to 22 nm, consistent with the 22-nm periodic structure deduced from x-ray diffraction studies and present in models proposed for hard alpha-keratin and other intermediate filaments. In the present study, we investigated the effect of 4-(2-aminoethyl)-benzenesulfonyl fluoride (AEBSF), a serine protease inhibitor, on PI3K inhibitor-induced CHOP expression. The ratio between the peak of IK and that of IA increased significantly between 24 h and 4 days in culture.

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