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Azilide (Azithromycin)
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Azilide

Azilide is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, and sexually transmitted diseases. In children, it is used to treat middle ear infection, pneumonia, tonsillitis, and strep throat.

Other names for this medication:
Amsati, Atizor, Azalid, Azifast, Azigram, Azihexal, Azimex, Azinil, Azithromycin, Azithromycinum, Azitral, Aziwok, Azomac, Aztrin, Azycyna, Bezanin, Binozyt, Disithrom, Doyle, Faxin, Ilozin, Iramicina, Koptin, Kromicin, Odazyth, Pretir, Sumamed, Talcilina, Tromic, Trozocina, Zistic, Zithrocin, Zithromycin, Zithrox, Zitrex, Zitrim, Zitrofar, Zitroken

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Also known as: Azithromycin

Description

Azilide (Azilide tablets and Azilide for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Azilide has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Azilide is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.

Azilide, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.

Azilide is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.

Azilide for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.

Dosage

Generic Azilide is available in: 250 mg (Low Dosage), 500 mg (Standard Dosage).

Generic Azilide can be taken in tablets, liquid form, injections. You should take it by mouth with water.

To avoid problems with stomach, take tablets and liquid form with meals. Liquid Generic Azilide form should be shook properly. Capsule is taken on empty stomach.

It is better to take Generic Azilide every day at the same time.

Generic Azilide treats different types of bacterial infections and can be used both by adults and by children. Thus, each age has different instructions.

For children it is better to take into account child weight. In treatment of otitis media, take Generic Azilide for 1-5 days.

For Adults: if you treat Pneumonia or Throat/Tonsil Infection the right dose is two tablets of 250 mg on the first day and then 250 mg once a day for 4 more days.

In prevention of MAC (mycobacterium avium complex) usual Generic Azilide dosage is 1,200 mg for a week.

In treatment of skin or infections usual Generic Azilide dosage is two tablets of 250 mg at the first day after you took one tablet of 250 mg for 4 days at the same time.

Overdose

If you take an overdose of Azilide you should visit your doctor or health care provider immediately. Symptoms of Azilide overdosage include discomfort in the stomach, diarrhea, retching and nausea.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not refrigerate or freeze the Zmax® extended-release oral suspension. After water has been added to the powder, use the dose within 12 hours and throw away any unused liquid after your dose.

You may store the Azilide® oral liquid at room temperature or in the refrigerator. Do not freeze the bottle. Do not keep the oral liquid for more than 10 days. Throw away any unused liquid after all doses are completed.

Detailed Azilide dosage information

Side effects

The most common side effects associated with Azilide are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies have not been performed on the relationship of age to the effects of azithromycin to treat sinusitis in children or to treat pneumonia in children younger than 6 months of age. Safety and efficacy have not been established in these age groups.

Appropriate studies have not been performed on the relationship of age to the effects of azithromycin oral suspension and tablets to treat pharyngitis or tonsillitis in children younger than 2 years of age. Safety and efficacy have not been established.

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Natural variation in seed dormancy is controlled by multiple genes mapped as quantitative trait loci in major crop or model plants. Twenty-one patients (20 females and 1 male, mean age 36, range 20-55 years) were included in the study. Cis-dicarbonyl binding at cobalt and iron porphyrins with saddle-shape conformation. Our approach additionally captures the notion that alternative clusterings may reside in different subspaces (or views). Ten minutes after PB injection for sentinel lymph node detection during breast cancer surgery, a 49-year-old woman developed generalised acute blue urticaria and eyelid angioedema without bronchospasm or haemodynamic disturbance, but requiring discontinuation of surgery.

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A novel HCV NS3 protease mutation selected by combination treatment of the protease inhibitor boceprevir and NS5B polymerase inhibitors. Experimental results indicate that the proposed approach is effective in producing plausible and impressive bas-reliefs. Synergistic interaction of topographic features in the production of bone-like nodules on Ti surfaces by rat osteoblasts. Logistic regression was used to examine variables associated with gender differences in physical function. Structured review of articles identified in a search of a large electronic medical database. Topiramate-positive death-investigation and impaired-driving cases in Washington State. A MEDLINE search was carried out for any articles in dental journals pertaining to fibre-based post systems.

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Markers of oxidative stress in ICU clinical settings: present and future. Immunostaining clearly demonstrated that most of the tumour cells possessed immunoreactive ACTH, whereas salivary amylase was only found in occasional clusters of the tumour cells. The differential diagnosis of the erythrodermic patient in the emergency room can include drug eruptions (DRESS syndrome), Staphylococcal scalded skin syndrome, toxic shock syndrome, Kawasaki disease and Kawasaki disease-like Syndrome, and recalcitrant erythematous desquamating disorder. These sexually transmitted diseases are more common among homosexual and bisexual men than among heterosexuals. The zooplankton resource was severely depleted and only made a minor dietary contribution. Robertsonian translocations from thirteen unrelated individuals were studied by G, Q and C banding, and by autoradiography.

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The influence of the guiding properties of the channel waveguide on the resonator mode was studied with a nearly concentric resonator. These data provide new guidelines for association studies using purebred dogs that take into account population structure. Porous polyethylene implants in revision rhinoplasty: chances and risks. WBC count, CRP and IL-6 correlated significantly with the severity of appendiceal inflammation. However, we found no relationship between conduction velocity and the functional properties of bladder mechanosensitive afferent fibers in neurologically intact or spinal cord injured rats. Sex and recombination generate variation via processes that depend on an underlying complementarity between participants.

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