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Artisid (Indomethacin)

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Artisid helps in relieving moderate pain and reducing fever. It effectively alleviates pain and inflammation in conditions like rheumatoid arthritis, osteoarthritis, gout, and ankylosing spondylitis.

Other names for this medication:
Artid, Artisid, Donica, Ducain, Edcin, Idicin, Indmecin, Indoc, Indocap, Indocid, Indoflam, Indol, Indomethacin, Indonet, Indopar, Indoriv, Inmecin, Inocin, Methadocin, Microcid, Recticin, Tissop

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Also known as: Indomethacin


Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) used to help relieve symptoms of moderate to severe arthritis (eg, osteoarthritis and rheumatoid arthritis) or gout, such as inflammation, swelling, stiffness, and joint pain. However, this medicine does not cure arthritis and will help you only as long as you continue to use it.

Indomethacin is also used to treat moderate to severe ankylosing spondylitis, which is a type of arthritis that affects the joints in the spine. This medicine may also be used to treat painful shoulder caused by bursitis or tendinitis.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain indomethacin. It may not be specific to Artisid. Please read with care.

For safe and effective use of this medicine, do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. Using too much of this medicine may increase the chance of unwanted effects.

This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

When used for severe or continuing arthritis, this medicine must be used regularly as ordered by your doctor in order for it to help you. This medicine usually begins to work within one week, but in severe cases up to two weeks or even longer may pass before you begin to feel better. Also, several weeks may pass before you feel the full effects of this medicine.

Do not take rectal suppositories by mouth or use it in the vagina.

To use the suppository:

If the suppository is too soft to insert, chill it in the refrigerator for 30 minutes or run cold water over it before removing the foil wrapper. Remove the foil wrapper and moisten the suppository with cold water. Lie down on your side and use your finger to push the suppository well up into the rectum Remain lying down for about 15 minutes to keep the suppository from coming out before it melts. Make sure to wash your hands with soap and water before and after inserting this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For rectal dosage form (suppositories): For moderate to severe ankylosing spondylitis, osteoarthritis, or rheumatoid arthritis: Adults and children older than 14 years of age—One 50-milligram (mg) suppository, inserted into the rectum up to 3 times a day. Children up to 14 years of age—Use and dose must be determined by your doctor. For acute painful shoulder caused by bursitis or tendinitis: Adults and children older than 14 years of age—One suppository inserted into the rectum 3 to 4 times a day. Children up to 14 years of age—Use and dose must be determined by your doctor. For gout: Adults and children older than 14 years of age—One suppository inserted into the rectum 3 times a day. Children up to 14 years of age—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe drowsiness, stomach pain, or vomiting.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Artisid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Artisid if you are allergic to Artisid components. Do not take Artisid if you're pregnant or you plan to have a baby, or you are a nursing mother. Be careful with Artisid if you are taking angiotensin ii receptor antagonists such as candesartan (atacand), eprosartan (teveten), irbesartan (avapro), losartan (cozaar), olmesartan (benicar), telmisartan (micardis), and valsartan (diovan); beta blockers such as atenolol (tenormin), labetalol (normodyne), metoprolol (lopressor, toprol xl), nadolol (corgard), and propranolol (inderal); cyclosporine (neoral, sandimmune); digoxin (lanoxin); diuretics ('water pills') such as triamterene (dyrenium, in dyazide); lithium (eskalith, lithobid); methotrexate (rheumatrex); phenytoin (dilantin); and probenecid (benemid), angiotensin-converting enzyme (ace) inhibitors such as benazepril (lotensin), captopril (capoten), enalapril (vasotec), fosinopril (monopril), lisinopril (prinivil, zestril), moexipril (univasc), perindopril (aceon), quinapril (accupril), ramipril (altace), and trandolapril (mavik). It can be dangerous to use Artisid if you suffer from or have a history of seizures, parkinson's disease, depression or mental illness, or liver or kidney disease. Be careful with Artisid if you are planning to use indomethacin suppositories. Be careful with Artisid if you had proctitis (inflammation of the rectum) or have recently had rectal bleeding, asthma, frequent stuffed or runny nose or nasal polyps (swelling of the lining of the nose). Avoid alcohol. Be careful with Artisid if you are going to have a surgery. Avoid driving machine. Do not stop take it suddenly.

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The possibilities of success of colectomy in colic cancers complicated by large abscesses. ER-based calreticulin and HDEL proteins also accumulate within outgrowing bulges and remain enriched at tips of emerging hairs. This zone was stably preserved until the onset of prophase, whereas the contiguity of unbleached chromosome segments was lost to a variable extent, when the metaphase plate was formed. Through focus groups, we identified generalizable themes related to the visualization and interpretation of health information. Malondialdehyde (MDA) and formaldehyde (FA), products of lipid peroxidation, are the presumptive markers for the development of oxidative stress in tissues and plasmas. Emtricitabine/tenofovir disoproxil fumarate: a review of its use in HIV-1 pre-exposure prophylaxis. In this model, threonine deaminase, or some form of this enzyme, is involved in a positive control of the regulation of the branched-chain aminoacyltransfer ribonucleic acid synthetases. Like many colon tumors, VACO-411 is not growth inhibited by TGF-beta. The prehispanic savanna peoples of the Bolivian Amazon built an anthropogenic landscape through the construction of raised fields, large settlement mounds, and earthen causeways. Alterations of Rb, p16(INK4A) and cyclin D1 in the tumorigenesis of oral squamous cell carcinomas.

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Novel and highly diverse fungal endophytes in soybean revealed by the consortium of two different techniques. Effects of compounds acting on the gamma-aminobutyric acid (GABA) and 5-hydroxytryptamine (5-HT) systems have been extensively investigated after both systemic administration and microinjection into specific brain regions. This is particularly evident in the liver and gut which are the major sources of this sterol in the plasma. These results suggest that the combination of anti-apoptotic and neurotrophic factors might enable the use of aNSCs derived from the SCZ in cortical neurogenesis for neural replacement therapy. We compared the insulin-mimetic effects of vanadate, a protein-tyrosine phosphatase inhibitor, with the effects of insulin on skeletal muscle glucose transport and insulin receptor and insulin receptor substrate 1 phosphorylation to test the hypothesis that protein-tyrosine phosphatases participate in pregnancy-induced insulin resistance.


The alterations induced by HCB within 1 week of treatment could be regarded as an initial trigger for irreversible damage on heme metabolism. In this study, we have addressed the question whether the modified Rossmann fold in 17betaHSD1 is a target for identification of lead compounds for structure-based drug design. These data, together with the topographic relationships of the dental follicle to areas of localized bone resorption and formation, are interpreted to mean that the dental follicle may influence, if not coordinate, these processes in tooth eruption. The translated instrument needs to be tested over time with other Hispanic populations. To study the biological activity of the ShdA protein, we examined its expression and binding activity.

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We used a checklist to identify barriers and possible interventions to address these in an iterative process that included a review of the literature, brainstorming, focus groups, a pilot study, small group discussions and interviews. Silent myocardial ischemia detected by single photon emission computed tomography (SPECT) and risk of cardiac events among asymptomatic patients with type 2 diabetes: a meta-analysis of prospective studies. Screening for Chlamydia trachomatis specific antibodies is valuable in diagnosing asymptomatic pelvic inflammatory disease (PID) and tubal damage following repeated episodes of PID. The practice of laparoscopic surgery for benign ovarian tumour during pregnancy is associated with benefits and harms. The case demonstrates the importance of examining tracer deposition within the entire field of view on (99m)Tc-macroaggregated albumin perfusion lung scintigraphy for extrapulmonary findings. The role of intraoperative magnetic resonance imaging in complex meningioma surgery. Pathophysiological roles of interleukin-8/CXCL8 in pulmonary diseases. On the contrary, knock down of TLE4 repressed cell proliferation, invasion and tumor growth. Quantative air sampling, a contrast with the settling-plate method for the study of bacterial air contamination in operating rooms. Therefore, a critical need exists to identify new compounds that have efficacy against drug-resistant malaria strains.

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On certain physico-chemical changes occurring in sonic-treated skin in relation to its formative capacity. Preferential consumption of coagulation factors I, V, and VIII in rat endotoxemia. Challenges in diagnosing tuberculosis in children: a comparative study from Sudan. This decrease results from the excretion of porphyrin precursor coproporphyrinogen III (CPgenIII), an intermediate in the biosynthesis of PpIX. A substantial proportion of these patients will, however, experience transient or permanent loss of personal independence within the first few months to years on dialysis.

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Systems for collaborative delivery of health care: guidelines for implementing cooperative programs. Adverse pregnancies were classified either in terms of loss (adverse non-live pregnancy/births) or in terms of live births in difficult circumstances (adverse live pregnancy/births). The nitrogen removal performance was substantially better than the level predicted by process stoichiometry, due to multiple anoxic configuration inducing additional nitrogen removal. In this era, technologies are becoming available that allow the profiling of tissues and cell populations at the genomic, transcriptomic and proteomic levels. Influence of dibutyryl cyclic adenosine monophosphate on motility of sperm. Botulism among pheasants and quail, mode of transmission, and degree of resistance offered by immunization.

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Only initial cell viability before inoculation was lower for the paralytic group, compared to the control group. We report a very unusual collision tumor composed of both a dermatofibroma and a melanocytic nevus mimicking melanoma. The cholesterol micelle is heterogeneous in size, probably rodlike in shape, and stabilized by an unusually high interaction energy between the aggregated monomers. The purpose of this study was to evaluate the pharmacokinetics of aminoglycosides in critically ill trauma patients receiving once-daily dosing regimens. Time to contrast enema and ileostomy closure rates following low anterior resection: does laparoscopic surgery make a difference?. Exercise-deficit disorder (EDD), which is a new term to the literature, is defined as reduced levels of moderate-to-vigorous physical activity, inconsistent with public health recommendations. Down-regulated STAT3 messenger ribonucleic acid and STAT3 protein in the hypothalamic arcuate nucleus of the obese leptin-deficient (ob/ob) mouse. In this open label clinical study of active JIA, both infliximab and etanercept provided a significant rapid and sustained reduction in disease activity. Only in 6 patients the spine, which is the common site of osteitis caused by tuberculosis, was affected.

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Subjects underwent (1)H-MRSI and were given the N-back working memory test. Study of events leading cellular senescence to human mammary epithelial cancer cells in vitro. A retrospective review of programme data of the Lagos state TB and the Leprosy control programme in Nigeria from 1 January 2012 to 31 December 2012. Role of sigma(B) in adaptation of Listeria monocytogenes to growth at low temperature. Amblyopia is best treated early in life to achieve a successful outcome. In the previous paper, boundary conditions matching the probe to the crystal wave function in scanning transmission electron microscopy were applied by matching the whole wave function across the boundary. Also detection systems are discussed, including UV-Vis, diode array, electrochemical and fluorimetric. Diagnostic guidelines are based on ICD-10 criteria for diagnosis of schizophrenia. Reversible pressure-induced disassembly of several viruses has suggested the idea of using hydrostatic pressure to suppress virus infectivity.

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The chemical and electrochemical techniques pertaining to the synthesis of metal nanoparticles, polymeric nanostructures and metal-polymer nanocomposites at liquid/liquid interfaces are surveyed. Adrenocortical and post-pituitary hormones during treatment of certain neurological comas. Sheep given one dose of lipid emulsion plus Rift Valley fever vaccine developed significantly higher antibody titers than control sheep receiving only vaccine. In these cases, there is a need to determine the severity of glaucoma, mainly on the basis of optic nerve head (ONH) and retinal nerve fibre layer (RNFL) structure. Bio-chemo-mechanical models for nuclear deformation in adherent eukaryotic cells. The efficiency of intranasal subcutaneous, aerosol and digestive vaccinations with killed Klebsiella pneumoniae as vaccine was studied on the survival curves after experimental disease with pathogen K.

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Using the Zelen design in randomized controlled trials: debates and controversies. Epifluorescent microscopic observation of human-ejaculated sperm nuclei stained with diamide-acridine orange. Even though subglottic dilatation provides symptomatic relief, recurrences may present. It is established that rotation and immobilization stress produces bidirectional effect on AFC number in spleen and on proliferative response of splenocytes. To update the information on the geographic distribution of bat-transmitted rabies foci in Colombia and evaluate the biotic and abiotic conditions associated with the incidence of this disease in the country. Malignant lymphoma was suspected because the patient had increased levels of serum LDH and an abnormal Ga scintigraphy finding in his chest. Biological and ecological peculiarities of midges in addition to the above data on the isolation of viruses define the perspectives of virusological examination of midges, primarily in Transcaucasia, Middle Asia, southern regions of Siberia and Far East of the USSR. The location error of point A was higher if the tandem was rotated away from the gantry-rotation-axis or if the location of the tandem flange was set away from the isocenter. Individual systemic reactions of human organism under acute hypoxia. Additional tests were done to investigate the concentricity of the sensors tip against the core of the optical fiber guiding the optical signal.

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Keloids are benign, fibroproliferative lesions that represent abnormal healing resulting in excessive fibrosis. The aim of this study was to evaluate the relationship between bcl-2 expression and risk of gastric cancer allergic reaction to differin gel recurrence. Specific targeting of endogenously synthesized antigens to the class II loading compartment can result in massively enhanced presentation of peptide epitopes. We also found that the cities that received funding in the early years of the program were more economically distressed than cities receiving the funding more recently. The designed conduits were investigated by physical, mechanical and microscopic analyses. Early treatment, for example, involving a logopedist, can be effective. Most clinically important vertebral body compression fractures in nontrauma patients at risk for low bone mineral density may go unreported at abdominal multidetector CT if sagittal reconstructions are not routinely evaluated. The regulation of myelopoiesis as approached with in vivo and in vitro techniques. Realigning Medicare: further changes in general practitioner consultation delivery rates. Along with food safety issues due to mycotoxins, the effects of Fusarium infections on malt and beer quality can be disastrous.

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Enhancing catalytic performance of Au catalysts by noncovalent functionalized graphene using functional ionic liquids. Recent studies reveal the importance of micro-level pollution information, including human personal exposure and acute exposure to air pollutants. Neither o-octopamine nor o-synephrine were found in urine under conditions by which 1 ng mg-1 creatinine would have been detected. However, decamethonium did not block all cholinergic nerve endings-for example, it did not diminish either the effects of stimulation of the chorda tympani on the submandibular salivary gland or those of pelvic nerve stimulation on the bladder. Diabetic foot risk stratification systems predict foot ulceration. To prevent osteoporosis and its dramatic complications in RA the therapeutic challenge is to preserve functional capacity using the lowest possible dosage of corticosteroids. Digestive performance and digesta passage in the omnivorous greater bilby, Macrotis lagotis (Marsupialia: Peramelidae). Resolution of tracheostomy complications by decanulation and conversion to noninvasive management for a patient with high-level tetraplegia.

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The clinical actos medication type relevance for measurement of nasal NO in different conditions, however, remains to be established. The presenting symptom is usually hoarseness, and the laryngoscopic appearances frequently mimic a tumor or chronic non-specific laryngitis: few patients correspond to the classical descriptions of the disease found in old texts. The um18 mutation prematurely truncated Vegfc, blocking its secretion and paracrine activity but not its ability to activate its receptor Flt4. Particularism in bioethics: balancing secular and religious concerns. A shutoff and exonuclease mutant of murine gammaherpesvirus-68 yields infectious virus and causes RNA loss in type I interferon receptor knockout cells. Durability of the binding inhibition of albumin coating on tympanostomy tubes. Single-molecule folding studies provide information concerning the distributions of conformational states in the folded, unfolded, and dynamically interconverting states.

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An adult patient with varicella-zoster pneumonia while under inhaled steroid treatment. Thus, loud snoring may not be a trivial symptom and should be considered as important in medical assessments. Their structures were determined spectroscopically, which included 2D NMR spectroscopic analysis. Bisphosphonate-associated osteonecrosis of the jaws (BP-ONJ) is known since 2003 with an increasing incidence in the first years. All patients underwent evaluation including a structured urogynecological questionnaire, voiding diary, pelvic examination using the POP-quantitation system, and urodynamic testing before and after surgery, and intraoperative cystoscopy. Hypoxia inducible factor-1 mediates upregulation of urokinase-type plasminogen activator receptor gene transcription during hypoxia in cervical cancer cells. These energies show a perfect correlation with the bond distance in the transition state between zinc and the methylene unit of the ethyl group being transferred. It may be difficult to differentiate this little known distinct pathological entity clinically from AA.

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Antiarrhythmic effects of amiodarone evaluated by dynamic electrocardiography. Better understanding of the underlying mechanisms leading to severe dengue is crucial if we are to develop prognostic markers, novel diagnostics and therapeutics and ultimately a balanced and safe vaccine. The purpose of this research was to identify the relationship between task performance and menstrual cycle. Generalized lymphadenopathy and hepatosplenomegaly induced by diphenylhydantoin. We discuss our findings in the context of specific viral infections and use our model to interpret empirical data. On the history of the water supply of populated sites of Armenia in the Middle Ages. Prolapse of the fallopian tube after hysterectomy associated with exuberant angiomyofibroblastic stroma response: a diagnostic pitfall.

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New unstable haemoglobin (Hb Moscva, beta24 (B4) Gly leads to Asp) found in the USSR. Hypertension and nephrosclerosis: a reappraisal and a new theory of renal ischemia. These findings are evidence that SUC1 is a structural gene for invertase and that both large and small forms are encoded by a single gene. There is a lack of evidence concerning risk factors for behavior problems and psychiatric disorders among VPT/VLBW survivors. Intestinal and fecal lipids in the rat subjected for long periods to a lipid-free diet. These steeper slopes may reflect the occurrence of a nonexchangeable PAH fraction in the aerosols, likely associated to the soot carbon phase. Australasian College of Sports Physicians-position statement: the place of mesenchymal stem/stromal cell therapies in sport and exercise medicine.

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Antibodies are detectable by an agglutination technique in the blood meals of hematophagous Diptera that are fed on laboratory and domestic animals infected with organisms of the Trypanosoma brucei subgroup. Partial tumor excision with T11-L2 laminectomy was undertaken and the tumors in the spinal cord were consistent with the diagnosis of epithelioid MPNSTs. In 86 patients, pre-dialysis remeron pill dosages serum HGF, soluble endothelial markers--such as thrombomodulin (TM), von Willebrand factor and plasminogen activator inhibitor-1--and hepatitis B and C markers were measured by ELISAs. These considerations have led to the development of Transimmunization, so named because it causes transfer of tumor antigens to newly formed dendritic cells capable of initiating immunization against the tumor cells, as the replacement technology for ECP. At surgery, there was significant ossification of the arachnoid/dura, which was removed. Different behavior of ghost-linked acidic and neutral sialidases during human erythrocyte ageing. We investigated structural and dynamical features of the two STAT5 isoforms, STAT5a and STAT5b, taken into account their phosphorylation status.

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We observed that flocked and foam swabs were superior to non-flocked swabs, BHI media was better than PBS, and transporting swabs wet was better for virus recovery and detection than transporting them dry. Gastric cancer is highly invasive, aggressively malignant, and amongst the most prevalent of all forms of cancer. As has been shown, Sydnocarb produces a slow and gradual increase of the parameters of dopaminergic dysfunction. More than one third of patients admitted with acute stroke are hyperglycaemic at presentation. Clinical and radiological findings after follow-up for 15 to 30 years. Studies on formycin and formycin B in cells of Ehrlich carcinoma and E.

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In cancer, metastasis lipitor 80 mg once a day genes are dysregulated at the levels of expression or splicing. The results from the current experimental study improved the understanding regarding the interplay between granulation time and the axial and solid-liquid mixing responsible for the granulation performance in twin-screw wet granulation. The other case provided what we believe to be the first description of PBS caused by severe phimosis. These data indicate that the depolarization of the cytoplasmic membrane by these peptides did not correlate with bacterial cell lethality. The TZDs including pioglitazone have been identified as high affinity ligands for peroxisome proliferator-activated receptor (PPAR) gamma. The outcome is closely associated with the severity of the illness, and age is of little influence.

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Remodeling of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor subunit composition in hippocampal neurons after global ischemia. The present study was undertaken to examine whether diabetic patients in the Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms (PRISM-PLUS) study appeared to benefit from platelet glycoprotein IIb/IIIa receptor-mediated inhibition of platelet aggregation by tirofiban. The character of GDNF mRNA expression was accordant to the process of nerve regeneration. So we propose a modified Wald interval for a single proportion, which can be calculated on a pocket calculator. A total of 31 proteins have been categorized into CEP family protein category and many more are under candidate evaluation. Patients with intraductal papillary mucinous neoplasms of the pancreas are not at an increased risk for the development of adenomatous colorectal polyps.

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