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Apine (Atenolol)

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Apine is a beta blocker that works specifically on the heart. It works by slowing down the heart rate and makes the heart more efficient at pumping blood around the body. Apine is also used to relieve the symptoms caused by an overactive thyroid gland.

Other names for this medication:
Aamin, Amdepin, Amdinx, Amdip, Amloat, Amlop, Amlopin, Amlotec, Amloten, Amnol, Amvik, Atark, Atcardil, Atcom, Atloma, Atnol, Atoli, Atzee, Calbeta, Cardimec, Cardpin, Cardules, Catenol, Cinamat, Glipin, Harten, Hynorm, Joglit, Lonet, Lonol, Malodip, Myamlo, Nifetolol, Niftene, Nipidol, Obeta, Odinol, Ozoten, Pdnol, Pericard, Pertenol, Syten, Teenol, Vascodil, Ziblok

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Nexium, Nimotop, Terramycin, Sporanox, Micardis

Also known as: Atenolol


Apine is created by pharmacy specialists to combat angina, heart attack, high blood pressure, anxiety attacks and migraine. Target of Apine is to influence circulation. Apine is also known as Atenolol, Hipres, Atendol, Altol, Atelol, Antipressan, Atenix, Ateno, Betacard, Blokium, Catenol, Corotenol, Notenol, Oraday. Apine acts as an anti-angina remedy. Apine operates by controlling and decreasing the strength of heart contractions and, thus, influencing circulation. Apine is a beta-blocker. You can use Apine with other anti-high blood pressure medication. Generic name of Apine is Atenolol. Brand name of Apine is Apine.


Usual Adult Dose of Apine for Hypertension:

Initial dose: 50 mg orally once a day Maintenance dose: 50 to 100 mg orally once a day Maximum dose: 100 mg per day Comments: -If desired response not achieved after 1 to 2 weeks, increase to 100 mg may be beneficial. -Doses greater than 100 mg once a day did not result in significant additional antihypertensive effects. Use: For the treatment of hypertension alone or in combination with other antihypertensive agents.

Usual Adult Dose of Apine for Angina Pectoris Prophylaxis:

Initial dose: 50 mg orally once a day -Increase to 100 mg orally once a day after 1 week if optimal response not achieved Maintenance dose: 50 to 200 mg orally once a day Maximum dose: 200 mg per day Comments: -Some patients may require 200 mg per day to attain optimal effect. Use: For the long-term management of angina pectoris due to coronary atherosclerosis.

Usual Adult Dose for Angina Pectoris:

Initial dose: 50 mg orally once a day -Increase to 100 mg orally once a day after 1 week if optimal response not achieved Maintenance dose: 50 to 200 mg orally once a day Maximum dose: 200 mg per day Comments: -Some patients may require 200 mg per day to attain optimal effect. Use: For the long-term management of angina pectoris due to coronary atherosclerosis.

Usual Adult Dose of Apine for Myocardial Infarction:

50 mg orally twice a day or 100 mg orally once a day Comments: -If IV beta blockers are contraindicated or inappropriate, oral therapy should continue for at least 7 days post-myocardial infarction (MI). -Treatment with beta blockers post MI should generally continue for 1 to 3 years if there are no contraindications. Use: For the management of hemodynamically stable patients with definite or suspected acute myocardial infarction to reduce cardiovascular mortality.

Usual Geriatric Dose for Hypertension:

Initial dose: Consider reducing the starting dose to 25 mg orally once a day

Detailed Apine dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include extreme weakness or lack of energy, very slow heart rate, shortness of breath, or fainting.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Apine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Apine if you are allergic to Apine components. Do not take Apine if you're pregnant or you plan to have a baby. Do not use potassium supplements or salt substitutes. Do not use Apine in case of suffering from heart block or severely slow heartbeat. Be careful with Apine usage in case of having bronchitis, depression, liver, heart or kidney disease, diabetes, low blood pressure, myasthenia gravis, thyroid disorder, pheochromocytoma, emphysema, asthma, problems with circulation. Be careful with Apine usage in case of taking cold medicines, stimulant medicines, or diet pills; clonidine (Catapres); MAO inhibitor (isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil) or selegiline (Emsam, Eldepryl); diabetes medication as insulin, glyburide (Micronase, Glynase, Diabeta), glipizide (Glucotrol), chlorpropamide (Diabinese) or metformin (Glucophage); heart medication as nifedipine (Procardia, Adalat), reserpine (Serpasil), verapamil (Calan, Verelan, Isoptin), diltiazem (Cartia, Cardizem); asthma medicines or other breathing disorders as albuterol (Ventolin, Proventil), bitolterol (Tornalate), metaproterenol (Alupent), pirbuterol (Maxair), terbutaline (Brethaire, Brethine, Bricanyl) and theophylline (Theo-Dur, Theolair); allergy treatments; guanabenz (Wytensin). If you want to achieve most effective results without any side effects it is better to avoid alcohol. Be very careful when you are driving machine. Do not stop taking Apine suddenly.

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We measured the uptake of 3-O-methyl-beta-D-glucose by dispersed islet cells from rats after a 15-minute incubation with purified IgG from 27 patients with newly diagnosed IDDM, 28 normal subjects, and 5 patients with non-insulin-dependent diabetes mellitus (NIDDM). Comparison of conventional and three-dimensional conformal CT planning techniques for preoperative chemoradiotherapy for locally advanced rectal cancer. Care in a distinct unit by a consistent multidisciplinary SBU team using quality improvement methods improved outcomes in ELBW infants. In addition, compared with CT group, the levels of plasma IL-6 and IL-1 were increased clearly in the four stress groups, and the contents of serum norepinephrine and dopamine in SCT and SLG groups were decreased dramatically. Positive pressure dilated the VP, but tongue muscle contraction did not cause further dilation under these conditions. Similar results were obtained in DSC experiments, where incorporation of NTA into liposomal membranes shifted the main transition temperatures and caused a broadening of the main transition peaks depending on the alkyl chain length. Proton-pump inhibitor therapy for acetylsalicylic acid associated upper gastrointestinal symptoms: a randomized placebo-controlled trial. The morphology of the plant-egg-interface was investigated in three species by histological studies and scanning electron microscopy. African American and Hispanic women, such as those living in the northern Manhattan and the South Bronx neighborhoods of New York City, are generally underserved with regard to breast cancer prevention and screening practices, even though they are more likely to die of breast cancer than are other women. We also discuss work examining the role of the hippocampus in visual feature binding.

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Epigenetics in embryonic stem cells: regulation of pluripotency and differentiation. It is a homotetramer of the rare C4-symmetric type with N-terminal domains protruding like antennas from the main body. The aims of this study were firstly to evaluate the relations between N-terminal pro-brain natriuretic peptide (NT-proBNP) concentration after ST-segment elevation myocardial infarction (STEMI) and reperfusion injury, and secondly to assess the prognostic value of NT-proBNP. Fifteen non-AMPV avian viruses belonging to 7 genera and 32 AMPV belonging to the 4 subgroups were tested. HPV16 VLPs cause phenotypic maturation of murine bone marrow-derived DCs (BMDCs), and immunization of mice with HPV16 VLP-loaded BMDCs or HPV16 VLPs alone induced T helper 1 (Th1)-biased immune responses. The family conference: end-of-life guidelines at work for comatose patients.

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Here we describe a differential requirement for Sgo1 in the segregation of homologous chromosomes and sister chromatids. The improvement can be ascribed to the carbon fibers as the highway for electrons and the interspace between NiO-CoO nanoneedles to accommodate the volume change and maintain the structural stability. A systematic review was conducted of community-based nutrition and physical activity strategies for chronic disease prevention targeting low-income populations. We set out to synthesize a series of fluorescein-labelled O-mannosylated peptides using manual solid phase peptide synthesis (SPPS) on pre-loaded Wang resin, in order to test their ability to bind mannose receptors on human APCs in vitro. Localization and content of nerve growth factor in peripheral blood eosinophils of atopic dermatitis patients. In-stent restenosis occurs as a localized lesion, commonly associated with a discontinuity in stent coverage.

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Validation of a Soft Tissue Sarcoma Nomogram Using a National Cancer Registry. Polycythaemia vera and essential thrombocythaemia: current treatment strategies. Development of self-administered versions of modified baseline and transition dyspnea indexes in COPD. Furthermore, similar to cells treated with p38 inhibitors, intestinal epithelial cells expressing Y1045F EGFR mutants show increased proliferation but not migration in response to EGF, thus uncoupling these biological responses. This quantitative method opens the way to numerous studies on the pathway of this protein-tracer through the glomerular substructures in the normal and pathologic rat. Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: role of p21Cip1 repression. Screening for vancomycin-resistant enterococci using stools sent for Clostridium difficile cytotoxin assay is effective: results of a survey of 300 Patients in a large Singapore Teaching Hospital. Oxidative stress and glutamate-mediated excitotoxicity may play an important role in the etiopathogenesis of amyotrophic lateral sclerosis (ALS). Ten-year data were compared to 1-year results to assess visual stability over time. Medical records from a random sample of 300 patients in The Swedish Heart Surgery register were reviewed with register data items systematically re-reported.

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Influence of fulvic acid and hydroxy propyl-beta-cyclodextrin on aspirin degradation. Not considering the complications due to anesthesia, postoperative hemorrhage is certainly the most frequent complication following tonsillectomy. Multifocal posterior chamber IOLs were stable and well centered. Enhancement of growth and polysaccharide production in suspension cultures of protocorm-like bodies from Dendrobium huoshanense by the addition of putrescine. Report on therapeutic work and classification of case histories in ophthalmological clinics. The nucleotide sequence of estA is highly conserved in the xanthomonads, and the sequence was used to design a specific PCR primer set.

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Water Intake by Outdoor Temperature Among Children Aged 1-10 Years: Implications for Community Water Fluoridation in the U.S. BB0323 function is essential for Borrelia burgdorferi virulence and persistence through tick-rodent transmission cycle. This is significantly more effective than a similar dose of arabinosyl cytosine (ara-C) given by rapid infusion. In another experimental group, chondroitin sulphate (CS), a newly described mediator of vascular repair, was added to normal culture medium, to search for possible additional benefit. Combining all, results suggest that taurine could protect hepatic tissues against Cd-induced oxidative stress probably through its antioxidant activity. Microheterogeneity of chondroitin sulfates from various cartilages. For the few remaining patients needing further characterisation, MTO-PET is advantageous as an additional imaging modality. To explore the effect of cold preservation and reperfusion injury (CPRI) on the bile salt spectrum in rat orthotopic liver transplantation (OLT) model.


Synthesis and characterization of meso-aryl-substituted subchlorins. IL-27 differentially regulates the gene expression between CD4 T cells and MDM. Unusual pattern of somatosensory and brain-stem auditory evoked potentials after cardio-respiratory arrest. Currently, no studies have been conducted to determine ubiquitin expression and its possible anti-apoptotic effects in endometriosis. Melatonin administration was associated with a dramatic decrease in microglial activation and astroglial reaction compared to untreated GR pups. Plasma s-Met level in normal pregnant women changed in a gestation-dependent manner, peaking at weeks 19-24.

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Aggressive lipid management for cardiovascular prevention: evidence from clinical trials. Seven years ago nurse Dee Winzar was given a life sentence for murdering her husband Nic McCarthy. Therefore, we herein report the first case of MCNS that attained complete remission following therapy for chronic sinusitis alone, which suggests a strong etiology of chronic sinusitis for MCNS. Removal of the side-chain glucose groups from schizophyllan improves the thermal stability of the polycytidylic acid complexes under the physiological conditions. However, they raise the question if vaccines, which try to emulate protective natural immune responses, should elicit an equally broad range of responses to efficiently convey protection. Manifestation of eosinophilic granulomatosis with polyangiitis in head and neck. These data suggest that GALP induces differential effects on energy balance and brain activity in mice compared to rats, which are unlikely to be due to activation of the GALR2 or GALR3 receptor. Bone marrow and brain: unexpected allies or accidental acquaintances?.

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The correlation matrix derived from these tasks did not exhibit positive manifold, that is, positive correlations across all problem-solving tasks. Differentially expressed genes were identified by Rosetta Resolver Gene Expression Analysis System. Human periostin gene expression in normal tissues, tumors and melanoma: evidences for periostin production by both stromal and melanoma cells. Octamer transcription factors and the cell type-specificity of immunoglobulin gene expression. This objective of this study is to investigate the effects of the radiolabeled cyclic peptide 153Sm-DTPA-c(CGRRAGGSC) on MHCC97-H human liver cancer cells in vitro and in vivo. The compression effect results from the difference of the durations of the interfering pulses and from their phase modulation. Evaluation of surgical methods in treatment of high blood pressure.

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Immunoreactive dynorphin B in sacral primary afferent fibers of the cat. Regardless of HIV serostatus, the IVB MIP-1 beta level was significantly lower in women with PM-associated anemia. In this paper, highly accelerated parallel MRI is used to acquire large 3D abdominal volumes with two different contrasts within a single breath-hold. To investigate the occurrence of myofibroblasts (MFBs) in the normal conjunctival surface and to evaluate any anatomical and time-related variations. Suppressor cell activity after concanavalin A treatment of lymphocytes from normal donors. Yeast RNA polymerase I (Pol I) contains approximately 15 phosphate groups, distributed to 5 of the 14 subunits.

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Cyclic AMP stimulation was not detectable in CHO-LHR and CHO-FSHR cells after incubation with M22 IgG, whereas incubation with hCG or FSH, respectively, caused dose-dependent cyclic AMP stimulation. Third epidemiological study of participants in the UK atmospheric nuclear weapons tests. This article is an effort to clear up a complicated matter for which there are not now accepted standards. In this study, we show that Sipa1l3/SPAR3 is conserved across species, has a distinct expression pattern in the developing rat brain and is localized at excitatory postsynapses. The liquid-crystal prisms function as low-cost, integrable, lowangle birefringent prisms. The influence of alpha, beta-methylene ATP on alpha 1-receptor-operated channels in guinea-pig taenia caeci. Based on microarray data (GEO: GSE19804), we observed that CCNB2 was significantly overexpressed in NSCLC tissues compared with paired adjacent normal lung tissue. Two common eating disorders--anorexia nervosa and bulimia nervosa--have significant medical complications. Dogs were sedated first without any pretreatment and then after pretreatment with metaflumizone and amitraz. We obtained four-phase contrast-enhanced scans using a 16-MDCT unit.

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Potential failures are distributed across the entire medication process, occurring mostly at the time of medication prescription and during preparation for drug administration. The cells treated with NP-BBN-SAN complexes showed greater DNA damage compared with other treatments. No decrease in allograft function could be attributed to acute rejection. Quality parameters were the quality grade how much money does amiodarone cost of mesorectal excision, the pathohistological involvement of the circumferential resection margin and intraoperative local dissemination of tumor cells. Decreased cerebrospinal fluid/plasma ratio of the novel satiety molecule, nesfatin-1/NUCB-2, in obese humans: evidence of nesfatin-1/NUCB-2 resistance and implications for obesity treatment. OCT4B expression in PBMNCs suggests the existence of an alternative OCT4 promoter. Spinal glioblastomas multiforme (GBMs) are rare lesions of the central nervous system with a prognosis as poor as that of their intracranial counterpart.

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The 65K variant was synthesized first as a preprotein of 49.5K which was processed to a polypeptide of 59K in the presence of microsomal membranes. There were no readmissions for suspected pelvic inflammatory disease or for other complications. In the normal rat retina ganglion cell axons are not myelinated until they enter the optic nerve. The composition of hydrogels had an important effect on ketoprofen release. The regioselectivity of deacetylation was found to be independent of the prevailing conformation of the substrates in solution as determined by 1H-NMR spectroscopy. A study of tumor motion management in the conformal radiotherapy of lung cancer. The usefulness of PRT as a primary screening test for prostate cancer was evaluated. Recombinant DNA-derived consensus alpha interferon was expressed in Escherichia coli and purified. Cell cycle transitions are often accompanied by the degradation of regulatory molecules. (4) States with the highest percentage of rural Medicare beneficiaries enrolled in MA and other prepaid plans include Minnesota (49.1 percent), Hawaii (41.1 percent), Pennsylvania (35.4 percent), Wisconsin (34.3 percent), New York (30.4 percent), and Ohio (30.1 percent).

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Age-dependent isotype variation during secondary immune response in MRL/lpr mice producing autoanti-gamma-globulin antibodies. BPV-1 DNA was demonstrated in all sarcoid epidermis samples, with viral DNA loads ranging between 2 and 195 copies/cell. To investigate the expression characteristics of protooncogene c-jun and its related gene p38 in different developmental intestinal epithelial cells in rats, and to explore their biological roles in the intestinal wound healing after injury. Entomopathogenic nematodes, insects, bacteria and their relationship used in practice. Differential patterns of cortical activation as a function of fluid reasoning complexity. Such models have also shown that treatment of obese female mice with estrogens has the potential to improve obesity, insulin resistance and glucose intolerance, via decreased expression of lipogenic genes. This author outlines some of the fundamental principles in environment. Role of a baclofen 20 mg dosage chalcone isomerase-like protein in flavonoid biosynthesis in Arabidopsis thaliana. Characterizations of environmental factors in conjugated linoleic acid production by mixed rumen bacteria.

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After completion of this article, the reader should be able to state the prevalence of idiopathic hydramnios, recall the lack of data relating to outcome, explain that there is a 2- to 5-fold increase in the risk of perinatal mortality, and summarize the lack of consensus in monitoring pregnancies afflicted with idiopathic hydramnios. Capacitance as a function of temperature at low surface charge is determined for 1:1, 2:2, 2:1, and 3:1 electrolytes. Endostatin associates with lipid rafts and induces reorganization of the actin cytoskeleton via down-regulation of RhoA activity. Comparison of motionally narrowed coherent anti-Stokes Raman spectroscopy line shapes of H(2) with hard- and soft-collision models. Among those are: availability of the treatment, consent for cadaveric donation, allocation of available organs, new categories of living unrelated donors and economic aspects of this method of treatment. After the recombinant bacmids had been determined to be correct by both blue-white colonies and PCR analysis, the isolated bacmid DNAs were transfected into Sf9 insect cells. Pyracetamat and cyticholine improved training of rats while the other examined substances showed insignificant effect.

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The maximally attainable VO2 during exercise in humans: the peak vs. Upon induction of these proteins, mutation rates increase by several orders of magnitude. Fecal samples at defined time points before, during, and after the period of yogurt ingestion were collected and analyzed. The current work is the first study where such a method was employed successfully not only with cells suspended in the medium with a rather high concentration of potassium (4-5 mM) but also with cells that release some part of intracellular potassium responding, in this way, to the stress caused by manipulation procedures during the preparation of the cell suspension. The present study showed a strong positive association between phthalate metabolites in urine and symptoms of ADHD among provigil 200 mg oral tablet school-age children.

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Platelets function physiologically in mediating hemostasis, but are also associated with many pathological conditions, such as thrombosis, which can lead to myocardial infarction and/or stroke. Exposure analysis of the effect of air pollution by carbon disulfide. Antitumor activity was studied on mouse Ehrlich ascites carcinoma (EAC) by means of evaluation of tumor (ascites) volume and mean lifespan (MLS). In this study we describe the external and internal structure of this organ. In this study, we focused our interest on the role played by COX-2 in apoptosis induced in HT-29 human colorectal cancer cells by ursolic acid (UA), a triterpenoid found in a large variety of plants. A monoclonal antibody obtained from mice immunized with a crude neurofilament preparation from newborn rat brain revealed the existence of heterogeneity of the 200,000- and 150,000-dalton neurofilament polypeptides. However, plants typically produce these compounds in low quantities, and harvesting plant natural products is frequently expensive, time-consuming and environmentally damaging. The mental health effects of disaster and terrorism have moved to the forefront in the recent past following the events of 11 September 2001 in the United States.

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Sensory nerve action potential on the foot disappeared more rapidly than CMAP. To report the trend in prescriptions and cost of antidiabetic drugs and glucose monitoring equipment in England from 1991 to 2004. Our studies have provided valued new insight into chromatin composition in plants. A total of 200 clinical isolates were collected and identified in our institution during 2005. Our results indicate that partial gene silencing identifies novel gene/phenotype relationships, which are distinct from those uncovered by knockout screens. In this paper, we propose a novel visual exploration approach that combines the abstract parameter space of the geometry generator with the resulting 3D shapes in a composite visualization. Cz-Fz amplitude differences increased with increasing stimulus intensity, the differentiating peak being the N1 component. These enzymes can then further degrade fibronectin to generate additional fragments, leading to the creation of a positive feedback loop, which may be of significance in disease processes.

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