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Anreb (Losartan)

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Anreb is used to treat patients with chronic heart failure when therapy with specific medicines called angiotensin-converting-enzyme inhibitors (ACE inhibitors, medicine used to lower high blood pressure) is not considered suitable by your doctor. If your heart failure has been stabilised with an ACE inhibitor you should not be switched to Anreb.

Other names for this medication:
Anreb, Aratan, Araten, Cardzaar, Cormac, Covance, Cozzar, Fensartan, Hilos, Insaar, Lopernal, Lopress, Losartanum, Losatrix, Losazid, Losium, Lozar, Medzar, Normatens, Osartil, Ozarium, Portiron, Ranlozar, Rasoltan, Sarvas, Satoren, Tacicul, Tiasar, Xartan, Zaart

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Also known as: Losartan


Anreb is indicated for the treatment of hypertension in adults and pediatric patients 6 years of age and older, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and nonfatal cardiovascular (CV) events, primarily strokes and myocardial infarction. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including losartan.

Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than 1 drug to achieve blood pressure goals. For specific advice on goals and management

Anreb is indicated to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy, but there is evidence that this benefit does not apply to Black patients

Anreb is indicated for the treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria in patients with type 2 diabetes and a history of hypertension. In this population, Anreb reduces the rate of progression of nephropathy as measured by the occurrence of doubling of serum creatinine or end stage renal disease


Usual Adult Dose for Diabetic Nephropathy:

Initial dose: 50 mg orally once a day Maximum dose: 100 mg orally once a day Comments: -If hypertensive patients with left ventricular hypertrophy or type 2 diabetic nephropathy patients require titration from initial dose, increase to 100 mg orally once a day. -Antihypertension is substantially present within 1 week but in some studies the maximal effect occurred in 3 to 6 weeks. Uses: -Treatment of hypertension. -To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. -Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio 300 mg/g or greater) in patients with type 2 diabetes and a history of hypertension.

Usual Adult Dose for Hypertension:

Initial dose: 50 mg orally once a day Maximum dose: 100 mg orally once a day Comments: -If hypertensive patients with left ventricular hypertrophy or type 2 diabetic nephropathy patients require titration from initial dose, increase to 100 mg orally once a day. -Antihypertension is substantially present within 1 week but in some studies the maximal effect occurred in 3 to 6 weeks. Uses: -Treatment of hypertension. -To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. -Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio 300 mg/g or greater) in patients with type 2 diabetes and a history of hypertension.

Usual Pediatric Dose for Hypertension:

6 Years or Older: Initial dose: 0.7 mg/kg orally once a day (up to 50 mg total) Comments: -May be given as a tablet or suspension. -Doses above 1.4 mg/kg (or 100 mg) daily have not been studied in pediatric patients.

Detailed Anreb dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Anreb are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Drinking alcohol can further lower your blood pressure and may increase certain side effects of Anreb.

Do not use potassium supplements or salt substitutes, unless your doctor has told you to.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

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Polysaccharides isolated from Echinacea purpurea herba cell cultures to counteract undesired effects of chemotherapy--a pilot study. Electrocautery has a potential risk of serious pacemaker dysfunction in patients with implanted pacemaker. OxRNA exhibits a positive twist-stretch coupling constant, in agreement with recent experimental observations. The other patient, however, died after developing renal and cardiopulmonary complications of lupus, including Libman Sachs endocarditis and pulmonary hypertension. Haemodynamic action of thymoxamine (an alpha-adrenergic blocking agent) in occlusive peripheral arterial disease. Comparison of complete mitochondrial genomes of pine wilt nematode Bursaphelenchus xylophilus and Bursaphelenchus mucronatus (Nematoda: Aphelenchoidea) and development of a molecular tool for species identification. An explanation for the occurrence of internal faults in porcelain jacket crowns. Oral administration of Bifina to HD patients is effective in reducing the serum levels of indoxyl sulfate by correcting the intestinal microflora. The final models included between 4 and 11 independent variables, and c-statistics ranged from 0.79 to 0.90.

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On the mechanism of renal inability to produce a concentrated urine in chronic hydronephrosis. A strict application of a period of abstinence as a policy for transplant eligibility is unfair to non-responder patients, as most of them will have died prior to the end of the six-month sober period. To investigate cardiovascular effects of changed GABAergic tonic activation in periventricular forebrain, arterial pressure (AP), heart rate (HR) and renal sympathetic nerve discharge (RSND) were recorded in anesthetized rats when L-securinine diflucan 50 mg (L-Sec) was administered into the lateral intracerebroventricle. This shows the therapeutic effect of MTX in controlling the immunopathogenesis of psoriasis. The results suggest that abrin can potentiate the humoral immune response of the host. Increased hippocampal NgR1 signaling machinery in aged rats with deficits of spatial cognition. Bismuth tungstate photocatalyst was synthesized by facile microwave hydrothermal method and the morphology evolution was investigated under wide range of microwave irradiation time.

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People living in community with a severe mental illness: utilization and satisfaction with care and support. Chromatic dispersion mitigation in long-haul fiber-optic communication networks by sub-band partitioning. Effect of the organic modifier and the mobile phase composition. What do patients with head injuries remember about their time of hospitalization?. In this review, we discuss drugs with epigenetic properties that have been identified as potential therapeutic agents in the treatment of diabetes and obesity, including those currently in clinical trials. In this study, the impact of adaptation to low pH and salt in a cheese- evista dosage based medium on L. Early brain atrophy in HIV infection: a radiological-stereological study. Effect of chlorhexidine mouthrinse and periodontal treatment upon bacteremia produced by oral hygiene procedures.

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The de novo assembly of mitochondrial genomes of the extinct passenger pigeon (Ectopistes migratorius) with next generation sequencing. Insights into ascorbate regeneration in plants: investigating the redox and structural properties of dehydroascorbate reductases from Populus trichocarpa. We synthesised data using a fixed-effect model and reported typical risk ratio (RR), risk difference (RD), and weighted mean difference (WMD). The effect of pneumonia on mortality among patients hospitalized for acute stroke. The phycobilisomes from both mutants lack the 33.5 x 10(3)-dalton polypeptide. The relatively novel technique of correlograph analysis (i.e., the approach of calculating angular autocorrelations within diffraction patterns) promises unique advantages for probing the local symmetries of disordered structures.

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