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Amotrex (Metronidazole)

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Flagyl is an oral antiprotozoal and antibacterial. It is thought to work by entering the bacterial cell, acting on some components of the cell, and destroying the bacteria. Treating certain infections caused by bacteria or amoebas. It may also be used for other conditions as determined by your doctor.

Other names for this medication:
Aminidazole, Amotrex, Avidal, Buccoval, Diazole, Efloran, Elyzol, Etron, Flagystatin, Flagystatine, Fortagyl, Giardyl, Menilet, Metrazol, Metrobac, Metrocev, Metrocream, Metrodal, Metronidazole, Metronidazols, Metrozine, Missilor, Nipazol, Orogyl, Rosalox, Rosasol, Rozex, Taremis, Tolbin, Trichex, Trogyl, Venogyl, Zyomet

Similar Products:
Sumycin, Tricor, Propecia, Differin, Singulair, Periactin

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Also known as: Metronidazole


{name} (metronidazole) is an antibiotic that is used to treat bacterial infections of the vagina, stomach, liver, skin, joints, brain and spinal cord, lungs, heart, or bloodstream.

{name} is also used to treat trichomoniasis, a sexually transmitted disease caused by a parasite. Usually both sexual partners are treated at the same time, even if one has no symptoms.

Do not use {name} to treat any condition that has not been checked by your doctor.


This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Amotrex. Please read with care.

Use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine is to be used only in the vagina. Use it at bedtime, unless your doctor tells you otherwise.

Do not get it into your eyes, nose, mouth, or skin. If this medicine does get into your eyes, wash them out right away with large amounts of cool tap water. If your eyes still burn or are painful, check with your doctor.

This medicine comes with a patient information leaflet and patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Wash your hands with soap and water before and after using this medicine.

Nuvessa™ is available inside a prefilled applicator. The applicator is open at one end where you will insert the plunger and has a pink cap on the other end where the medicine will come out.

Vandazole® is in a tube. You will use an applicator to put the gel into your vagina. The applicator has a plastic tube called a barrel that is open at one end and has a plunger (another piece of plastic that can move inside the barrel) at the other end.

To use the medicine:

To fill the applicator: For cream or gel dosage forms: Nuvessa™: With the pink cap still on, push the tip of the plunger into the open end of the prefilled applicator. Pull the cap off before you insert the applicator into your vagina. Vandazole®: Break the metal seal at the opening of the tube by using the point on the top of the cap. Screw the applicator onto the tube. Squeeze the medicine into the applicator slowly until it is full. Remove the applicator from the tube. Replace the cap on the tube. For vaginal tablet dosage form: Place the vaginal tablet into the applicator. Wet the vaginal tablet with water for a few seconds. To insert vaginal metronidazole using the applicator: For all dosage forms: Relax while lying on your back with your knees bent (or in any position that you feel comfortable). Hold the full applicator in one hand. Insert it slowly into the vagina. Stop before it becomes uncomfortable. Slowly press the plunger until it stops. Withdraw the applicator. The medicine will be left behind in the vagina. Remove the applicator from your vagina. Use each applicator only once, and then throw it away.

To help clear up your infection completely, it is very important that you keep using this medicine for the full time of treatment, even if your symptoms begin to clear up after a few days. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses. Also, continue using this medicine even if your menstrual period starts during the time of treatment.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For bacterial vaginal infections: For vaginal dosage form (cream): Adults—One applicatorful (500 milligrams [mg]), inserted into the vagina. Use the medicine 1 or 2 times a day for 10 or 20 days. Children—Use and dose must be determined by your doctor. For vaginal dosage form (gel): Nuvessa™: Adults and children 12 years of age and older—One applicatorful (5 grams [g]) inserted into the vagina once (at bedtime). Each applicatorful of Nuvessa™ contains 65 mg of metronidazole. Children younger than 12 years of age—Use and dose must be determined by your doctor. Vandazole®: Adults—One applicatorful (5 grams [g]) inserted into the vagina once a day (at bedtime) for 5 days. Each applicatorful of Vandazole® contains 37.5 mg of metronidazole. Children—Use and dose must be determined by your doctor. For vaginal dosage form (tablets): Adults—One 500 milligram (mg) tablet, inserted high into the vagina. Use the medicine once a day in the evening for 10 or 20 days. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting, and loss of balance or coordination.


Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

Side effects

The most common side effects associated with Amotrex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Psychotic Reaction with Disulfiram. Use of oral metronidazole is associated with psychotic reactions in alcoholic patients who were using disulfiram concurrently. Do not administer metronidazole to patients who have taken disulfiram within the last two weeks.

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Anaphylaxis-conditioned circulatory disorders in the rabbit heart and its modification by the coronary dilator substance 1-p-ethoxyphenyl-3-diethylaminoindane. Correlation of myocardial Doppler velocity response to exercise with independent evidence of myocardial ischemia by dual-isotope single-photon emission computed tomography. Surgical care quality and oncologic outcome after D2 gastrectomy for gastric cancer. Recently, increasing attention has been paid to the use of extracellular vesicles (EVs) as delivery systems. Our results suggest that neurotrophins dental pulp cells, SHED cells and neural like cells derived from SHED cells produce neurotrophic factors.

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Home MI-E use by children with NMD can reduce hospitalisation and benefit families by maintaining their child at home. To account for influences on the single scoring criteria, such as the baseline noise, multivariate classification models were derived. To determine whether the enhancement of threshold sural sensory nerve action potentials (SNAPs) occurred in patients with spinal cord injury after upper limb isometric contraction. Energy functions in de novo protein design: current challenges and future prospects. Sample sizes were small, pneumonia definitions were variable and blinded outcome assessment was infrequent. A 6-month-old male infant was treated with intravenous infusions and enteral feed via a naso-gastric tube. Part 1: synthesis of deoxy and partially O-methylated glycolipids with or without a sulfur containing spacer. The influence of a lower removable partial denture on the tissues of the gingival margin of the remaining teeth.

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Lung cancer is the leading cause of cancer mortality in the United States, and its incidence is growing throughout the world. Related viruses within the same group, Louping ill virus (LIV), Langat virus (LGTV) and Powassan virus (POWV), also cause human encephalitis but rarely on an epidemic scale. To investigate the expression of MMP-12 by SMCs, we examined the protein secretion and mRNA expression of MMP-12 by cultured medial SMCs and intimal SMCs derived from human aortic atherosclerotic lesions. A syndrome combining severe hypotrichosis and macular dystrophy: absence of mutations in TIMP genes. However, NADPH-cytochrome P-450 reductase prevented incorporation of P-450 by this method, a phenomenon possibly inherent in the formation of complexes between P-450 and the reductase in solution.

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Potential reasons for the change in outcomes include better patient selection and improvement indevice technology. On the problem of the significance of various forms of lymphocytes in clinical hematological diseases. The data supports the hypothesis that adenosine mediates is klonopin a controlled drug a tonic suppression of synaptic transmission. Known Brr2p interaction sites of the Jab1/MPN domain remain available, suggesting that Aar2p-mediated compaction of the Prp8p domains sterically interferes with Brr2p binding. However, cue reactivity at posttreatment did not contribute to the prediction of outcome at follow-up over and above posttreatment outcome.

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Our results show that cleavage efficiency can vary significantly for individual HAs, depending on the protease, and that some HA subtypes display stringent selectivity for specific proteases as activators of fusion function. Robotic testing could act as an adjunct to the manual clinical examination by supplying numbers that could improve diagnosis of knee injury. Outcome measures were oxygen saturation, growth of the babies, and the need for surgery. In search of social phobia subtypes: similarity of feared social situations. At cut section, the catarrhal fluid was draining from the airways. In contrast to their effect on the striatum, neither BAC nor NaV influences hypothalamic-pituitary DA function mediating PRL secretion. Traditional progestogen-only pills (POPs) have stringent daily timing and missed pill rules that might affect contraceptive reliability. PBPK model describes the effects of comedication and genetic polymorphism on systemic exposure of drugs that undergo multiple clearance pathways. Following this scheme, all six species could be clearly discriminated.

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(1) Growth and mental development of infants can be improved by touch. Zones in the eastern portion of the city consistently had significantly higher Culex abundance and VI compared with zones in the west, leading to higher entomological risk indicators for human WNV infection in the east. The total cholesterol (tC), LDL, triglyceride, HDL levels and tC/HDL were determined to analyze the impact of LLT. Midbrains of male Wistar rats were examined at various time points ranging from 4 h to 12 weeks after birth. Health care leaders must take great care with the cultural factors involved. 13 681 7 to 8-year-old singleton children who were invited to wear an accelerometer on their right hip for 7 consecutive days.

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A subjective analysis and chart review were performed to determine the final outcome of these patients. Cancer survivors are less likely to give birth compared with the background population. A meeting was held in November 1997 to discuss clinical issues related to the classification. Cumulative release amount of each species versus square root of time how many mg of motrin can you take in 24 hours plot showed good linearity, indicating that the dissolution was controlled by the diffusion mechanism. Here we present an alternative analysis, in which dichotomized individual items of the questionnaire are analyzed. IgE-destroying activity could be inhibited by heat-inactivated serum, and by relatively high concentrations of crude alpha 1-antitrypsin, aprotinin, lima bean and soybean trypsin inhibitors and by p-nitroguanidinobenzoate. The nature of this material and the process responsible for its accumulation are still unknown. To identify the reactive species in the Fenton system, the oxidation of a series of different compounds (phenol, benzoic acid, methanol, Reactive Black 5 and arsenite) was studied for iron- and copper-catalyzed reactions at varying pH values. These new plasmonic nanostructures display extremely strong optical enhancing properties and can be readily used as platforms for SERS and for integration in ultrasensitive optical devices.

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To gain insight into their developmental roles, we investigated the mRNA expression patterns of both genes in developing mouse and chick limbs by in situ hybridization. sanguis M5 to sHA while partially inhibiting the attachment of S. To estimate whether live birth in single-blastocyst transfers is correlated with the number of sibling supernumerary vitrified blastocysts (embryos not transferred) generated from that same cycle. Several important physiological functions require the cooperation of microbiota/microbiome, whose alterations play an important role in several human diseases. The intervention programme encouraged the students to make healthy lifestyle choices related to eating habits and physical activity behaviours. The paper describes an advance in stray field imaging (STRAFI) whereby images of planar samples can be obtained in crestor dosage levels the stray field of a superconducting magnet without the need for sample rotation. Considerations on the distoposition of the second mandibular bicuspids.

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