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Alfatrim (Trimethoprim)

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Alfatrim is a combination of two synthetic (man-made) antibiotics, sulfamethoxazole and trimethoprim. Both drugs reduce the ability of some bacteria to utilize folic acid for growing. Sulfamethoxazole is an anti-bacterial sulfonamide, a sulfa drug.

Other names for this medication:
Adrenol, Alfatrim, Avlotrin, Bactramin, Balsoprim, Biotrim, Bismoral, Broncoflam, Cadiprim, Cosat, Cotrimstada, Cotripharm, Esbesul, Escoprim, Globaxol, Ifitrim, Kanprim, Megatrim, Oriprim, Primadex, Primazol, Regtin, Soltrim, Sumetoprin, Supreme, Sutrim, Trimesulf, Trimesulfin, Trimezol, Trimosazol, Tripur, Trisulfose, Trisulin, Vanadyl, Zaxol, Zoltrim

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Also known as: Trimethoprim


Sulfamethoxazole and trimethoprim combination is used to treat infections including urinary tract infections, middle ear infections (otitis media), bronchitis, traveler's diarrhea, and shigellosis (bacillary dysentery). This medicine is also used to prevent or treat Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP), a very serious kind of pneumonia. This type of pneumonia occurs more commonly in patients whose immune systems are not working normally, including cancer patients, transplant patients, and patients with acquired immune deficiency syndrome (AIDS).

Sulfamethoxazole and trimethoprim combination is an antibiotic. It works by eliminating the bacteria that cause many kinds of infections. This medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.


Adults: The usual adult dosage in the treatment of urinary tract infections is 1 Alfatrim DS (double strength) tablet or 2 Alfatrim tablets every 12 hours for 10 to 14 days. An identical daily dosage is used for 5 days in the treatment of shigellosis.

Children: The recommended dose for children with urinary tract infections or acute otitis media is 40 mg/kg sulfamethoxazole and 8 mg/kg trimethoprim per 24 hours, given in two divided doses every 12 hours for 10 days. An identical daily dosage is used for 5 days in the treatment of shigellosis.


If you overdose Generic Alfatrim and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Alfatrim overdosage: dizziness, drowsiness, nausea, vomiting, loss of appetite, stomach pain, headache, yellowing of your skin or eyes, blood in urine, fever, confusion, fainting.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Alfatrim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.

Alfatrim could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

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Linear growth and circulating insulin-like growth factor-I in children with tufting enteropathy receiving long-term TPN: retraction. Assessment of clinical benefit and quality of life in patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for management of peritoneal carcinomatosis. The amino acid analysis and the inhibition mechanism of the purified peptides are reported. Nursing is compelled by traditional views of nursing into taking a long-established and expected place in the health care hierarchy, which is reflected in current curricula. Our results indicated that there was a relationship between extensive injury legions and the H-reflex F- and M-responses in magnetically evoked EMGs. Bacteria Isolated From Respiratory Tract Specimens medication to counteract seroquel weight gain of Renal Recipients With Acute Respiratory Distress Syndrome Due to Pneumonia: Epidemiology and Susceptibility of the Strains.

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Zinc oxide nanoparticles induced specifically a strong decrease in the mitochondrial function, in phagocytosis and also an increase in the methylglyoxal-associated DNA damage, which may explain the well known genotoxicity of zinc. Disinfection and obturation of root canals in one operative session. Endothelial damage, platelet hyperactivity and other changes of blood coagulation may play a role in the vascular complications of essential hypertension. Overwhelming Postsplenectomy Infection: A Prospective Multicenter Cohort Study. The structures of the new compounds were elucidated on the basis of spectral evidence. RNA was isolated from individual brains and subjected to microarray and qPCR analysis. In a subgroup of 100 NC and 50 AD patients, both the STT and the Color Trail Test (CTT) were performed. Candida lusitaniae as an unusual cause of recurrent vaginitis and its successful treatment with intravaginal boric acid.

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The genotype of BVDV found in PI cattle can be predicted by the predominant neutralizing antibody titers found in tested heifers. A what type of medicine is levaquin rapid and efficient method for dissociated cultures of mouse myenteric neurons. Effect of rate-limiting elongation on bacteriophage MS2 RNA-directed protein synthesis in extracts of Escherichia coli. It proposes three main components to sustaining relationship quality when providing support to an intimate partner: showing respect, showing understanding, and showing caring. Bone-eating worms of the genus Osedax exclusively inhabit sunken vertebrate bones on the seafloor. Neural control of adipose tissue demonstrated by nerve stimulation, in vitro. The complex interactions of immune, endothelial, and neuronal cells that take place during inflammation require an equivalent complexity of imaging approaches to be appropriately explored in vivo. Effects of continuous enclosure and fertilization on soil microbial community structure in alpine meadow. However, a consensus as to what is the optimal blood compartment for the detection and quantitation of CMV DNA in peripheral blood is nonexistent. Dicresyl-methanedisulfonic acid in the treatment of cutaneous ulcerations of the lower extremities.

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