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Alendix (Alendronate)

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Alendix is FDA-approved for the treatment of postmenopausal osteoporosis, prevention of postmenopausal osteoporosis, steroid-induced osteoporosis, male osteoporosis, and Paget disease of the bone. Alendix is available under the following different brand names.

Other names for this medication:
Alant, Alendix, Alendronate, Alenost, Bifosa, Denfos, Osteofos, Ostogee, Poronil, Ralenost, Restofos, Zophost

Similar Products:
Symmetrel, Epivir, Tricor, Actos, Lexapro, Ativan, Astelin

Also known as: Alendronate


{name} Plus D contains a combination of alendronate and cholecalciferol. Alendronate is a bisphosphonate medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures.

Cholecalciferol is a form of vitamin D, and is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.

{name} Plus D is used to treat and prevent osteoporosis.


Generic Alendix should be taken orally. It is recommended to take Generic Alendix in liquid form once a week in the morning without food. It is recommended to take Generic Alendix in tablets of 5-mg and 10-mg once a day in the morning without food. It is recommended to take Generic Alendix in tablets of 30-mg and 70-mg once a week in the morning without food. It is recommended to take Generic Alendix in tablets of 40-mg once a day in the morning for six months to treat Paget's disease of bone. If you want to achieve most effective results do not stop taking Generic Alendix suddenly.


Drink a full glass of milk and seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Do not make yourself vomit and do not lie down.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alendix are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Alendix if you are allergic to alendronate, or if you have:

low levels of calcium in your blood (hypocalcemia); or problems with the muscles in your esophagus (the tube that connects your mouth and stomach).

Do not take Alendix if you cannot sit upright or stand for at least 30 minutes. Alendix can cause serious problems in the stomach or esophagus. You must stay upright for at least 30 minutes after taking this medicine.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

trouble swallowing; problems with your stomach or digestion; low levels of calcium in your blood; a dental problem (you may need a dental exam before you begin taking Alendix); kidney disease; or any condition that makes it hard for your body to absorb nutrients from food (malabsorption).

In rare cases, this medicine may cause bone loss (osteonecrosis) in the jaw. Symptoms include jaw pain or numbness, red or swollen gums, loose teeth, or slow healing after dental work. The longer you use Alendix, the more likely you are to develop this condition.

Osteonecrosis of the jaw may be more likely if you have cancer or received chemotherapy, radiation, or steroids. Other risk factors include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem.

Alendix has also been reported to cause fractures, or broken bones, in the large bones of the leg. Tell your doctor if you have any leg or groin pain while using Alendix.

Talk with your doctor about the risks and benefits of using this medication.

It is not known whether Alendix will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Stop using the medicine and tell your doctor right away if you become pregnant.

It is not known whether alendronate passes into breast milk or if it could harm a nursing baby. Ask your doctor about any risk.

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