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Aldactone (Spironolactone)

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Aldactone is a prescription medicine used to treat the symptoms of high blood pressure (hypertension), low potassium levels (hypokalemia) and heart failure. Aldactone may be used alone or with other medications. Aldactone belongs to a class of drugs called Aldosterone Antagonists, Selective, Diuretics, Potassium-Sparing.

Other names for this medication:
Aldostix, Amifru, Aquamide, Dyamide, Dytor, Fruselac, Frusis, Lactone, Lasilactone, Metolactone, Spilactone, Spiromide, Spironolactone, Spirotic, Torlactone, Tormax, Torsid, Zator

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Myambutol, Actos, Aurogra, Indocin, Glucotrol, Loxitane, Abilify, Lopid, Aldara

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Also known as: Spironolactone


{name} (spironolactone) is a potassium-sparing diuretic (water pill) that prevents your body from absorbing too much salt and keeps your potassium levels from getting too low.

{name} is used to treat heart failure, high blood pressure (hypertension), or hypokalemia (low potassium levels in the blood).

{name} also treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney disorder called nephrotic syndrome.

{name} is also used to diagnose or treat a condition in which you have too much aldosterone in your body. Aldosterone is a hormone produced by your adrenal glands to help regulate the salt and water balance in your body.


Usual Adult Dose of Aldactone for Edema:

25 to 200 mg orally per day in single or divided doses

Usual Adult Dose of Aldactone for Hypertension:

Initial dose: 50 to 100 mg orally per day in single or divided doses

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 25 mg orally once a day assuming serum potassium is less than or equal to 5 mEq/L and serum creatinine is less than or equal to 2.5 mg/dL

Usual Adult Dose for Primary Hyperaldosteronism:

Diagnostic dose:

Usual Adult Dose for Hypokalemia:

25 to 100 mg orally per day

Detailed Aldactone dosage information


If you overdose Generic Aldactone and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Aldactone overdosage: diarrhea, vomiting, nausea, red skin rash, loss of energy, slow heartbeat, weakness in legs, feeling drowsy, confusion.


Store below 25 degrees C (77 degrees F). Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Aldactone are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Drinking alcohol can increase certain side effects.

Do not use potassium supplements or salt substitutes, unless your doctor has told you to.

Avoid a diet high in salt. Too much salt will cause your body to retain water and can make this medication less effective.

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

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MDA concentrations in sperm were much less than in seminal plasma and motility and viability were inversely correlated with semen MDA levels. The tachykinin NK(1) receptor antagonist SR140333 prevents the increase of nerve growth factor in rat paw skin induced by substance P or neurogenic inflammation. Elemental modifications and polycyclic aromatic hydrocarbon metabolism in human fibroblasts. Evidence suggests that dietary fats are associated with risk of colorectal cancer. Application of the two-compartment open model with Michaelis-Menten elimination kinetics to valproic acid in the bile-exteriorized rat.

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Purification and characterization of a novel secondary fimbrial protein from Porphyromonas gingivalis strain 381. The diagnosis of extragonadal germ cell tumor and left renal cell carcinoma was confirmed pathologically by infraclavicular lymph node and renal biopsy. COMPUTER SYSTEMS AS CLINICAL AND PHYSIOLOGICAL DIAGNOSTIC METHODS. All simulations are two-dimensional phase-field computations using an adaptive finite element method. Altogether, the novel Pkd1(extra) mouse model is the first Pc1 extracellular mutant that reproduces human ADPKD clinical progression and physiopathology. Patients admitted in hospital with influenza A H1N1v pneumonia over a two year period were analysed.

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Clinical considerations of the causative mechanism of pregnancy toxemias. Use of radial forearm free flap can i take prilosec with thyroid medicine with palmaris longus tendon in reconstruction of total maxillectomy with sparing of orbital contents. This association was compared with the association between mortality and traditional risk factors in CKD mortality (diabetes, hypertension and smoking). Extracorporeal shockwave lithotripsy for renal stones in pediatric patients: a multivariate analysis model for estimating the stone-free probability. Narcissistic Patients: Understanding and Managing Feelings and Behaviors. Coronary artery reconstruction for extensive coronary disease: 108 patients and two year follow-up. In particular, ceramide-enriched membrane microdomains play extremely critical roles in LRs clustering or platform formations.

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Growth factors, cell damage, cyclin-dependent kinases and their inhibitors: relevance in molecular pathology of human cancer. DNA sequencing has revealed a frameshift mutation due to deletion of nucleotide C at position 3507 in exon 6, which gave rise to a stop codon resulting premature termination for translation. However, before a final conclusion on this matter can be drawn, a prospective randomized study should be undertaken. A new type of stilbene-related secondary metabolite, idenburgene, from Cryptocarya idenburgensis. In contrast, recent reports suggest that RSG causes growth arrest and apoptosis of normal and cancerous cells. On the 22nd week of her pregnancy she presented with a large distension of the anterior surface of the neck in the area of the thyroid that gradually increased in size. There are cost of cordarone a few reports of hem-o-lok clip migration into the bladder or vesico-urethral anastomosis and only four cases of hem-o-lok clip migration resulting into bladder neck contracture.

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Prospective study of vitamin D status at initiation of care in critically ill surgical patients and risk of 90-day mortality. Complicated Bochdalek hernia was an incidental finding, diagnosed by chest radiograph, computed tomography (CT), and barium swallow study. The large diversity of interneurons poses the question of whether they have specific roles in shaping distinct network activities in vivo. Use of gas chromatography-olfactometry to identify key odorant compounds in dark chocolate. Adsorption of an Isocyanurate Silane on E-Glass Fibers from Ethanol and Toluene. A quantitative real-time polymerase chain reaction analysis of the mRNA expression in eutopic and ectopic endometrial tissues with or without GnRH agonist treatment. The effect of cardiopulmonary bypass on tissue digoxin concentrations in the dog. We used unilateral fatigue applied to one arm in order to determine whether inter-hemispheric remapping can vary asymmetrically during a bilateral isometric matching task. Longitudinal regression models with family-level random effects were used to assess the patterns of change in child and parent (civilian and military) psychological health outcomes over time. Concerns have been raised regarding the potential complications and costs of routine stenting.

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Findings from this study provide useful information for planners of CE programs for APNs. The biological activity of this mycotoxin is mainly attributed to its estrogenic activity that modulates/disrupts endocrine function in animals and possibly humans. Three new compounds were isolated from the adult insect of Allomyrina dichotoma L. The results showed that chronic toxic potencies were correlated with several physico-chemical properties among eight species chosen, where the softness index was the most predictive characteristic. Uncoupling protein-2 could have particular importance in the regulation of lipid metabolism in adipose tissue and skeletal muscle. All images should be de-identified, randomized, and calibrated prior to analysis. Human data suggest that eplerenone and spironolactone lowers blood pressure by mechanisms independent of the distal tubule.

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To determine the concentrations of sCD40L in what drugs interact with lipitor patients with PAPS, and establish its association with the number of thrombosis. New possibilities and perspectives in the treatment of juvenile diabetes. We report that BTK regulates B-cell and macrophage-mediated T-cell suppression in pancreas adenocarcinomas. Nearly half the patients received initial treatment as outpatients without adverse consequences for their subsequent use of hospitalization. Given that the existence of F1 hybrids with intermediate interspecific morphologies has been proven in the Caribbean, hybrids may also inhabit the Indo-Pacific and occur more frequently than expected. Transcription of the Geminin gene is regulated by a negative-feedback loop.

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This study reviews the perioperative use of red blood cell transfusion in cerebrovascular neurosurgery. This has important implications for choosing the correct techniques to evaluate replicating viruses in culture. Lamina propria plasma cells in inflammatory bowel disease: intracellular detection of immunoglobulins using flow cytometry. In response, this study used eye-tracking technology to explore the degree to which people pay visual attention to the information contained in food nutrition labels and front-of-package nutrition symbols. Study of long-term pathologic effects of radioactive isotopes of calcium and strontium in bone and soft tissues, especially with reference to bone tumor production. Taken together, our studies indicated a novel cellular function of CCN1, potentially regulating the pathogenesis of PH. Profoundly immunosuppressed patients were more likely to die early in the course of treatment. Improvement of treatment plans developed with intensity-modulated radiation therapy for concave-shaped head and neck tumors. Increased C-reactive protein, electrocardiographic Q-wave, and impaired myocardial fatty acid metabolism are independently and synergistically related to sudden death risk in haemodialysis patients.

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Many therapeutic targets are intracellular proteins and molecules designed to interact with them must effectively bind to their target inside the cell. Thinking about breathing: Effects on respiratory sinus arrhythmia. Standardized rate ratios were calculated comparing the disease frequency, mortality, and cancer incidence with that of the general population of northern Sweden. The results demonstrate the capability of piezoelectric dispensing technology to precisely fabricate bilayer DMN. Applying sodium ferrocyanide did not show any alleviation effect on the seedling growth and nitrogen metabolism under salt stress. Studies of the effects of otitis media on cognitive development in children have not been extensive. Metabolite levels were examined in bone marrow samples extracted from metformin or PBS -treated is there a recall on zyrtec allergy medicine healthy (Wild type) and hyperglycemic (diabetic) mice using liquid chromatography-mass spectrometry (LC-MS)-based metabolomics. Estimation of PM2.5 Concentration over the Yangtze Delta Using Remote Sensing: Analysis of Spatial and Temporal Variations. Interventions included overnight blood sampling followed by GnRHag (leuprolide acetate) injection.

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