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Adlene (Adapalene)
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Adlene

Adlene is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also used off-label to treat keratosis pilaris as well as other skin conditions. Among topical retinoids used to treat acne vulgaris, Adlene is considered to be the least effective, but best tolerated.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Strattera, Zocor, Mircette, Sporanox, Mobic, Atarax, Zyrtec

Also known as: Adapalene

Description

Adapalene is used to treat acne. It works partly by keeping skin pores clear.

Adapalene is available only with your doctor's prescription.

Dosage

Follow the directions for using this medicine provided by your doctor. Use Adlene exactly as directed. Adlene is best applied after washing and drying your skin. Apply a thin layer of gel to the affected areas once daily at bedtime. Avoid the eyes, lips and nose. Do not allow this preparation to come into contact with the mucous membranes (e.g. mouth, vagina, inside of nose etc.). Try not to touch the treated areas overnight. Do not use any harsh soaps or exfoliants while you are being treated with Adlene. Adlene should not be used on broken, sunburnt or infected skin. You may notice a slight change of colour of the skin you are applying this preparation to. This is only temporary and should return to normal soon after finishing treatment with Adlene. Continue using Adlene until no new acne spots appear. You may need to use it for several months. You should notice some clinical improvement after 4-8 weeks and more improvement after further use. There may be a worsening of acne during the first few weeks of therapy because Adlene promotes the growth of pimples that have begun to form but are not yet visible. Therefore, treatment should not be stopped if acne appears to be worsening. Use a sunscreen cream and wear protective clothing if exposure to strong or prolonged sunlight cannot be avoided. Weather extremes such as wind or cold may also be irritating.

Overdose

If you overdose Adlene and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at a room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Adlene are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Adlene if you are allergic to Adlene components. It is not known whether Adlene will harm an unborn baby. Do not use this medicine without your doctor's advice if you are pregnant or breast-feeding. Do not get Adlene in your eyes or on the inside of your nose or mouth. For the first 2 to 3 weeks of treatment, your skin condition may appear to worsen. This is expected. Do not stop using the medicine during this time. Do not use other medicines on your skin without first discussing it with your doctor. While you are using Adlene, you may use cosmetics. After using cosmetics, thoroughly wash and dry the affected area before applying this medicine. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Adlene. Use a sunscreen if you must be outside. Do not apply it to sunburned skin. Do not stop taking Adlene suddenly.

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Molecular analysis of Berardinelli-Seip congenital lipodystrophy in Oman: evidence for multiple loci. Variations in the background activity level are associated with alterations of the experimental situation. These reiterations differ between levels and sites, suggesting the possible existence of cultural identities or behavioural predispositions dependant on groups. In this paper, a new supervised classification paradigm, called classifier subset selection for stacked generalization (CSS stacking), is presented to deal with speech emotion recognition. In nearly all sex-role reversed species or populations, females have higher potential reproductive rates than males. Clinical and morphological observations on a case of microdrepanocytosis. Nociceptin and nocistatin are endogenous ligands of G protein coupled receptor family. Chondroitin sulfate A released from platelets blocks RANTES presentation on cell surfaces and RANTES-dependent firm adhesion of leukocytes. Previously, we have found that disruption of one copy of the gene for either protamine 1 (PRM1) or protamine 2 (PRM2) in the mouse results in a reduction in the amount of the respective protein, abnormal processing of PRM2, and inability of male chimeras to transmit either the mutant or wild-type allele derived from the 129-genotype embryonic stem cells to the next generation.

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In vivo production of Rof and Tof proteins of HTLV type 1: evidence from cytotoxic T lymphocytes. An anionic phospholipid enables the hydrophobic surfactant proteins to alter spontaneous curvature. Reconstitution of an Initial Step of Phototropin Signaling in Stomatal Guard Cells. During blastula and gastrula stages, cells in the animal and marginal regions continue to express both genes uniformly. Effect of carbon dioxide on respiration and phosphorylation in cerebral cortex and liver tissues.

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Health locus of control, distress, and utilization of protease inhibitors among HIV-positive men. The objective of these analyses is to document the relationship between biomarker-based indicators of health and socioeconomic status (SES) in a low-income African population where the cumulative effects of exposure to multiple stressors on physiological functions and health in general are expected to be highly detrimental for the well-being of individuals. These results confirm the efficacy, tolerability, and ease of use of the leuprorelin implants among a large population of men with advanced, hormone-dependent prostate cancer treated in a clinical practice setting. We sought to investigate the relationship between sinonasal inflammation as assessed on computed tomography (CT) scanning, lung function, sputum eosinophilia, and nitric oxide (NO) in exhaled air in patients with severe asthma. FAK degradation was completely prevented by a caspase-3-specific inhibitor. Positive feedback was observed in normal intact males in response to a single subcutaneous injection of 35 micrograms oestradiol benzoate. The findings of such studies will lead to identifying the biological targets to treat this condition. Immunotherapy of the guinea pig line 10 hepatocarcinoma with a variety of nonviable bacteria.

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Long-lasting lozenges CU 701-1: dissolution duration times in patients with oral mucosal lesions. Promotion of alpha/beta interferon induction during in vivo viral infection through alpha/beta interferon receptor/STAT1 system-dependent and -independent pathways. The aim of the present investigation was to evaluate the transverse displacement of the proximal segment and ramus rotation after a bilateral sagittal osteotomy (BSO) with rigid internal fixation (RIF) using bicortical LAG screws. HIV auxiliary proteins: an interface between the virus and the host. C/EBP-beta, C/EBP-delta, PU.1, AML1 genes: mutational analysis in 381 samples of hematopoietic and solid malignancies. The available data in the literature on safety and benefits of exercise training in patients after LVAD implantation are limited, but the data that are available suggest that training trends to be safe and have an impact on exercise capacity in LVAD patients. Prospects for malaria eradication, with special reference to the Western Pacific. This example of cross-reactivity between Epstein-Barr virus and alpha-synuclein may bear implications for further elucidating infectious or autoimmune mechanisms in PD.

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Administrative validity and scientitic validity of the international anti-smallpox vaccination certificate. No protein-RNA complexes could be detected when using single-stranded oligoribonucleotides. The role of pathogenic Escherichia coli serotypes in diseases of young animals. An external factor, asbestos, is suspected to play a role in the genesis of peritoneal mesotheliomatosis. The results suggest an age-related contribution of ghrelin and motilin to the regulation of chicken GI motility. Temporal and spatial expression pattern of the OSVP1 and OSEM genes during seed development in rice. This suggests that some patients may experience suboptimal tumor cytotoxicity, whereas other patients may be at risk for excess toxicity. We report the case of a seventy-year old man, who had previously undergone vena cava filter implantation and who was admitted to the Intensive Care Unit due to acute respiratory distress with the suspect of pneumonia-related sepsis.

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