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Actalipid (Simvastatin)

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Actalipid is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular events including myocardial infarction and stroke. Actalipid is indicated for the treatment of hyperlipidemia to reduce elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL‑C), apolipoprotein B (Apo B), and triglycerides (TG), and to increase high-density lipoprotein cholesterol (HDL-C).

Other names for this medication:
Actalipid, Docsimvasta, Dosavastatin, Lipex, Lipinorm, Lodales, Normotherin, Simbastatin, Simgal, Simvastatin, Simvastatina, Simvastatinum, Simvofix, Sinvacor, Sivastin, Statinal, Vasilip, Zocord, Zorced, Zorstat, Zosta, Zostin, Zostine, Zovast, Zovastin, Zovatin, Zurocid

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Also known as: Simvastatin


Actalipid is an HMG-CoA reductase inhibitor. Actalipid is used to: reduce the risk of heart attack, stroke, and death due to coronary heart disease; reduce the risk of heart attack, stroke, blood vessel blockage, or chest pain caused by angina; low high cholesterol and triglycerides; increase high-density lipoprotein (HDL, "good") cholesterol levels. Actalipid is also known as Imvastatin, Simlup, Simcardis, Ranzolont, Simvador. Actalipid works by reducing the production of certain fatty substances in the body, including cholesterol. Generic name of Actalipid is Simvastatin. Brand name of Actalipid is Actalipid.


Take Actalipid exactly as prescribed. Follow all directions on your prescription label. Never take this medicine in larger amounts, or for longer than prescribed. Taking too much of this medication may cause serious or life-threatening side effects.

Actalipid is usually taken at bedtime or with an evening meal. If you take this medicine more than once daily, take it with meals. Your doctor may occasionally change your dose to make sure you get the best results.

While using Actalipid, you may need frequent blood tests at your doctor's office.

You may need to take Actalipid on a long-term basis for the treatment of high cholesterol. You may need to stop using this medicine for a short time if you have surgery or a medical emergency. Do not stop taking this medicine unless your doctor tells you to.

Actalipid is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture, heat, and light.

Detailed Actalipid dosage information


If you overdose Actalipid and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Actalipid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Actalipid if you are allergic to Actalipid components. Be careful with Actalipid if you're pregnant or you plan to have a baby. Do not use it if you are a nursing mother. Be careful with Actalipid if you suffer from low blood pressure, kidney problems, diabetes, serious infection, metabolism problems, hormonal problems. Do not use potassium supplements or salt substitutes. Avoid eating grapefruit or drinking grapefruit juice while taking Actalipid. While taking Actalipid, you can make laboratory tests (blood cholesterol levels, liver function tests, creatine phosphokinase blood levels) to monitor the condition of your health. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Be very careful when you are driving machine. Do not stop taking Actalipid suddenly.

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Epidemiologic studies implicate air pollutant exposure during pregnancy as a risk factor for wheezing in offspring. Overexpression of GABARAP in rat adrenal pheochromocytoma PC-12 cells increased the cell-surface expression of AT(1)R and Ang II-dependent activation of the cAMP signaling pathway. Predictive miRNAs could be potentially useful diagnostic markers, improving the classification of pituitary adenomas. The recommended phase II dose was then evaluated in a two-stage trial, with a primary end point of objective response rate. The proposed method is available on most of the MR scanners, thus T(1) and water mapping of human brain can be routinely performed. These results demonstrate the importance of G-protein in the maintenance and regulation of hSSTR dimers. Central nervous system and Alimentry system malformations were most frequent.

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Yolk coelomitis in a white-throated monitor lizard (Varanus albigularis). In the biopsies we found the equivalent of connective tissue attachment between vital tissue and the alloplastic material. Honey ameliorates influence of hemorrhage and food restriction on renal and hepatic functions, and hematological and biochemical variables. Echocardiographic study of the effects of acute left atrial hypertension on left atrial size. Nuclei are anatomical units of the central nervous system (CNS). Use of mean systolic ABPM or HBPM in the PROCAM formula had no major impact on the risk level.


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Functional somatic syndrome: from the viewpoint of narrative-based medicine. Effect of intrauterine administration of follicular and luteinic hormones. Therefore, an alternative approach is needed that will optimize the development of new products. High platelet counts may have some pathogenic significance in the obstruction of the ophthalmic circulation and a few cases of associated essential thrombocythaemia and GCA have been described. Apart from discomfort and pain in 5 patients, no major complications were encountered in the 33 patients studied. In response to venous congestion, capillary flow rate falls drastically, whereas Laser-Doppler flow is much less dramatically reduced. The incidence of 13q abnormality was different in various types of soft tissue tumors, indicating that alterations of Rb, RFP2, maxolon dose children KCNRG and KLF5 tumor suppressing genes may play diverse roles in different types of soft tissue tumor. We requested or examined relevant conference proceedings for appropriate trials. Determination of sitagliptin in human urine and hemodialysate using turbulent flow online extraction and tandem mass spectrometry. Using nonadecameric duplex deoxyoligonucleotide substrates, the specificity of the PaeR7 endonuclease for unmethylated, hemi-methylated, and fully methylated N6-methyladenine (m6A) and C5-methylcytosine (m5C) versions of these substrates has been studied.

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Salicylic-acid signaling is mediated by at least two mechanisms, one requiring the NON-EXPRESSOR OF PR1 (NPR1) gene and a second that is independent of NPR1. Locally advanced head and neck cancers: recommendations of an expert panel and perspectives for the use of TPF regimen (docetaxel, cisplatin and fluoro-uracil) as induction therapy. The aims of this study were to determine the magnitude of expenditures for common modes of promotion and to delineate patterns of promotional strategies for particular classes of medications. Ligaments were classified into three groups in terms of thickness and apparent strength following finger palpation, high, doubtful and low apparent quality ligaments. Survival of Trichinella papuae muscle larvae in a pig carcass maintained under simulated natural conditions in Papua what allergy medicine can i take with allegra New Guinea. The proposed approach is applied here to patients suffering from cysts and polyps that underwent micro-laryngoscopic direct exeresis (MLSD).

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Mean estimated elimination half-lives ranged from 0.7 d in silver carp muscle to 8.4 d in common carp liver. Antibiotic treatment according to the microbiological sensitivity test for eleven months ativan 25 mg resulted in complete remission of pulmonary and cerebral nocardiosis. Observations on the relationship of carotid pressure and end point during acceleration. This issue is clinically relevant because it broadens the understanding of the bone cell fate within the rather complex cosmos of the oral cavity thereby providing a basis for clinical decision making and treatment guidelines. The obtained results indicate that the function of the Na,K-pump in myocardial sarcolemma is rather stable and deteriorates only during extreme exertion. Study 3 evaluated the potential for armodafinil to inhibit the activity of CYP2C19 using oral omeprazole as the probe substrate. An enzyme, galactosyltransferase, able to catalyze the formation of galactose polymers was detected in cell-free extracts of a wild type strain of Neurospora crassa.

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Expression of thymidylate synthase and glutathione-s-transferase pi in patients with esophageal squamous cell carcinoma. Purification by affinity chromatography, properties and crystallisation of phosphofructokinase from thermophilic micro-organisms. Moxifloxacin superior to cefuroxime in reducing bacterial adhesion of Staphylococcus epidermidis on hydrophobic intraocular lenses. To explain this observation, from the data published on HLA-A11 crystallographic structure, we propose molecular models of the HLA-A3 molecule complexed with Nef73-82, Pol325-333, and Gag20-28 epitopes. Useful diagnostic imaging techniques include plain x-rays, computed tomography, and magnetic resonance imaging. A double-isotope procedure for examining protein microheterogeneity: multiple forms of fast-transported glycoproteins and sulfoproteins possess a common polypeptide chain.

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Correlation-induced changes in the degree of polarization, the degree of coherence, and the spectrum of random electromagnetic beams on propagation. Combined Experimental and Computational Studies of a Na2 Ni1-x Cux Fe(CN)6 Cathode with Tunable Potential for Aqueous Rechargeable Sodium-Ion Batteries. CG and EG showed improvement in almost all the assessment scales after treatment, although only some with relevant differences. Rapid intercellular molecule exchange takes place in wild-type filaments, but is completely abolished in the mutant, and this blockage obstructs any cell differentiation, indicating a fundamental importance of intercellular communication for cell differentiation in Nostoc. We propose that this regulated monomerization of 14-3-3 controls its ability to modulate the activity of target proteins and thus may have significant implications for 14-3-3 function and the regulation of many cellular processes.

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Neither the biological role of the MIF catalytic site nor the mechanistic details of CD74 activation are well understood. Cholestasis is more serious in IHS patients of cholestasis subtype. Transcranial magnetic stimulation studies give an evidence of a reversible corticobulbar conduction abnormality which resolved with clinical improvement. Epitopes of the 44-68 human parathyroid hormone fragments: the importance of specific hydrophilic peptide sequences. It is an integral membrane protein that does not contain an extended hydrophobic region of the kind often required for stable integration in the inner membrane. The Statement on Reporting of Evaluation Studies in Health Informatics (STARE-HI), by being recently endorsed by IMIA, EFMI and the EQUATOR Network, may therefore provide a generic objectives framework to help achieve common goals. By checking the polarity of each term in M and P, one might conclude if the plan was satisfied with the given treatment protocol. Comparing the different potato pulp sausages using various kinds of heat treatment of the potato pulp significantly lowered the frying loss and increased the firmness. Anti-infectives were the principal theme for the 1-day symposium following the workshops.

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A spiral-grooved endoesophageal tube for management of malignant esophageal obstruction. The advantages of this procedure are its simplicity and rapidity of execution, a reduced incidence of complications, and good tolerance in terms of patient pain and comfort. The measurement of 3beta-hydroxysteroid dehydrogenase in ovaries of fowls (Gallus domesticus). MercusalR, clopamide and triamterene did not affect water transport. Measurements of the root hydraulic conductance (L0) of roots of Arabidopsis thaliana were carried out and the results were compared with the expression of aquaporins present in the plasma membrane of A. Intensity-time curves were obtained from the manually selected regions of interest over the renal parenchyma and whole kidney for calculation of split renal function and assessment of urinary excretion, respectively. Moreover, the array was highly sufficient to investigate the gene content of non-pathogenic isolates, despite the strong bias towards pathogenic E. Mouse Leydig tumor cells expressing receptors for luteinizing hormone were specifically lysed in vitro as a consequence of complement fixation via the Fc component of the hybrid molecule.

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