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Abamune (Lamivudine)
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Abamune

Abamune is used to treat hepatitis B infection. Abamune is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV and hepatitis B in the blood.

Other names for this medication:
Abamune, Combivir, Duovir, Emduo, Emtri, Haptavir, Hepavud, Hepitec, Hepravir, Hivir, Ladiwin, Lamidac, Lamistar, Lamivir, Lamivox, Lamivudine, Lamostad, Lamuvid, Lavir, Lazid, Lmivir, Nevilast, Odivir, Retrolam, Shanvudin, Stadin, Stavex, Tenola, Tenolam, Tenvir, Trimune, Trioday, Viramid, Virolam, Virolis, Zidolam

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Also known as: Lamivudine

Description

Lamivudine is used in combination with other medicines for the treatment of the infection caused by the human immunodeficiency virus (HIV). HIV is the virus that causes acquired immune deficiency syndrome (AIDS).

Lamivudine will not cure or prevent HIV infection or AIDS. It helps keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay the development of serious health problems usually related to AIDS or HIV disease from occurring. Lamivudine will not keep you from spreading HIV to other people. People who receive this medicine may continue to have other problems usually related to AIDS or HIV disease.

Lamivudine is also used to treat chronic (long-term) hepatitis B virus (HBV) infection.

This medicine is available only with your doctor's prescription.

Dosage

Take Abamune exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. You should not take Abamune (for treating HIV) together with Abamune-HBV (for treating hepatitis B).

You may take this medicine with or without food.

Lamivudine doses are based on weight in children. Your child's dose needs may change if the child gains or loses weight. Children who weigh more than 30 pounds (14 kilograms) should use the tablet form if possible. The liquid form may not be as effective.

You may need to break a tablet in half when giving this medicine to a child for HIV. Call your doctor if the child has any trouble swallowing the tablet.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

The Abamune brand contains a higher dose of lamivudine than Abamune-HBV brand. Abamune is for treating HIV and Abamune-HBV is for treating hepatitis B. Each time you get a refill of this medication, be sure you have received the correct brand to treat your condition.

You will need frequent medical tests, including frequent HIV testing. If you become infected with HIV while you are taking lamivudine to treat hepatitis B, the HIV could become resistant to antiviral medicines if not treated right away.

The hepatitis B virus can mutate while you are taking Abamune-HBV and may become resistant to treatment. Resistant hepatitis B can lead to worsening liver disease or death. Tell your doctor if you have new or worsening hepatitis symptoms.

Use all HIV medications as directed and read all medication guides you receive. Do not change your dose or dosing schedule without your doctor's advice. Every person with HIV should remain under the care of a doctor.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

If you've ever had hepatitis B, this virus may become active or get worse in the months after you stop using Abamune. You may need frequent liver function tests while using this medicine and for several months after your last dose.

Detailed Abamune dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Lamivudine dosage information

Side effects

The most common side effects associated with Abamune are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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Abnormal steroid hormone production (in children)--special reference to microanalysis of urinary steroids by glass capillary gas chromatography and its application. Bacteria belonging to the genus Azospirillum isolated from Cynodon dactylon roots in Israel were compared with Azospirillum brasilense from Brazil and California for their ability to fix nitrogen in association with grasses under greenhouse conditions. Outcomes and predictive factors of pediatric kidney transplants: an analysis of the Thai Transplant Registry. Serotonergic mechanisms are necessary for central respiratory chemoresponsiveness in situ. 20 accident and emergency departments, 40 general practices, and 14 out of hours services within 3 km of a walk-in centre or the centre of a control town. High-throughput screening for protein-protein interactions using two-hybrid assay. One original aspect of this protocol is the video demonstration of the surgical procedure, which is available on the web to standardize and homogenize the technique. Terbium-sensitized luminescence determination of levofloxacin in tablets and human urine and serum. Only these right precordial leads at higher intercostal space positions were useful to identify Brugada syndrome in this case.

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Pseudomonas fluorescens is often described as a major PGPR (plant growth-promoting rhizobacterium), and our results suggest that there may be a connection between the T6SS and the PGPR properties of this bacterium. The first experiences with transmyocardial laser revascularization were made using a surgical approach. Above a threshold adhesive strength, the prefactor changes sign, the surfaces become sticky, and a finite force is required to separate them. This suggests that the MIM gene product is required for DNA repair by HR, but is not critical for HR induction. Microbial typing is often employed to determine the source and routes of infections, confirm or rule out outbreaks, trace cross-transmission of healthcare-associated pathogens, recognize virulent strains and evaluate the effectiveness of control measures.

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